BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

168 related articles for article (PubMed ID: 7980616)

  • 1. Production of Alzheimer 4kDa beta-amyloid peptide requires the C-terminal cytosolic domain of the amyloid precursor protein.
    LeBlanc AC; Gambetti P
    Biochem Biophys Res Commun; 1994 Nov; 204(3):1371-80. PubMed ID: 7980616
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Intracellular generation of amyloid beta-protein from amyloid beta-protein precursor fragment by direct cleavage with beta- and gamma-secretase.
    Iizuka T; Shoji M; Kawarabayashi T; Sato M; Kobayashi T; Tada N; Kasai K; Matsubara E; Watanabe M; Tomidokoro Y; Hirai S
    Biochem Biophys Res Commun; 1996 Jan; 218(1):238-42. PubMed ID: 8573139
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Missense mutations associated with familial Alzheimer's disease in Sweden lead to the production of the amyloid peptide without internalization of its precursor.
    Essalmani R; Macq AF; Mercken L; Octave JN
    Biochem Biophys Res Commun; 1996 Jan; 218(1):89-96. PubMed ID: 8573182
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Proteasome-mediated degradation of the C-terminus of the Alzheimer's disease beta-amyloid protein precursor: effect of C-terminal truncation on production of beta-amyloid protein.
    Nunan J; Williamson NA; Hill AF; Sernee MF; Masters CL; Small DH
    J Neurosci Res; 2003 Nov; 74(3):378-85. PubMed ID: 14598314
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Frame-shifted amyloid precursor protein found in Alzheimer's disease and Down's syndrome increases levels of secreted amyloid beta40.
    van Dijk R; Fischer DF; Sluijs JA; Sonnemans MA; Hobo B; Mercken L; Mann DM; Hol EM; van Leeuwen FW
    J Neurochem; 2004 Aug; 90(3):712-23. PubMed ID: 15255950
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The amyloid peptide precursor in Alzheimer's disease.
    Octave JN
    Acta Neurol Belg; 1995 Dec; 95(4):197-209. PubMed ID: 8553793
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Processing of the Alzheimer's disease amyloid precursor protein in Pichia pastoris: immunodetection of alpha-, beta-, and gamma-secretase products.
    Le Brocque D; Henry A; Cappai R; Li QX; Tanner JE; Galatis D; Gray C; Holmes S; Underwood JR; Beyreuther K; Masters CL; Evin G
    Biochemistry; 1998 Oct; 37(42):14958-65. PubMed ID: 9778373
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Targeting of cell-surface beta-amyloid precursor protein to lysosomes: alternative processing into amyloid-bearing fragments.
    Haass C; Koo EH; Mellon A; Hung AY; Selkoe DJ
    Nature; 1992 Jun; 357(6378):500-3. PubMed ID: 1608449
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Effect of alkalizing agents on the processing of the beta-amyloid precursor protein.
    Schrader-Fischer G; Paganetti PA
    Brain Res; 1996 Apr; 716(1-2):91-100. PubMed ID: 8738224
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells.
    Esposito L; Gan L; Yu GQ; Essrich C; Mucke L
    J Neurochem; 2004 Dec; 91(6):1260-74. PubMed ID: 15584903
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Presenilin 1 regulates the processing of beta-amyloid precursor protein C-terminal fragments and the generation of amyloid beta-protein in endoplasmic reticulum and Golgi.
    Xia W; Zhang J; Ostaszewski BL; Kimberly WT; Seubert P; Koo EH; Shen J; Selkoe DJ
    Biochemistry; 1998 Nov; 37(47):16465-71. PubMed ID: 9843412
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of amyloid precursor carboxy-terminal fragments enhances their processing by a gamma-secretase-dependent mechanism.
    Vingtdeux V; Hamdane M; Gompel M; Bégard S; Drobecq H; Ghestem A; Grosjean ME; Kostanjevecki V; Grognet P; Vanmechelen E; Buée L; Delacourte A; Sergeant N
    Neurobiol Dis; 2005 Nov; 20(2):625-37. PubMed ID: 15936948
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Formation of amyloid-like fibrils in COS cells overexpressing part of the Alzheimer amyloid protein precursor.
    Maruyama K; Terakado K; Usami M; Yoshikawa K
    Nature; 1990 Oct; 347(6293):566-9. PubMed ID: 1977086
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Defective neurite extension is caused by a mutation in amyloid beta/A4 (A beta) protein precursor found in familial Alzheimer's disease.
    Li HL; Roch JM; Sundsmo M; Otero D; Sisodia S; Thomas R; Saitoh T
    J Neurobiol; 1997 May; 32(5):469-80. PubMed ID: 9110259
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Membrane-anchored aspartyl protease with Alzheimer's disease beta-secretase activity.
    Yan R; Bienkowski MJ; Shuck ME; Miao H; Tory MC; Pauley AM; Brashier JR; Stratman NC; Mathews WR; Buhl AE; Carter DB; Tomasselli AG; Parodi LA; Heinrikson RL; Gurney ME
    Nature; 1999 Dec; 402(6761):533-7. PubMed ID: 10591213
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Proteasome inhibitors induce the association of Alzheimer's amyloid precursor protein with Hsc73.
    Kouchi Z; Sorimachi H; Suzuki K; Ishiura S
    Biochem Biophys Res Commun; 1999 Jan; 254(3):804-10. PubMed ID: 9920821
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteolytic processing of the Alzheimer's disease amyloid precursor protein in brain and platelets.
    Evin G; Zhu A; Holsinger RM; Masters CL; Li QX
    J Neurosci Res; 2003 Nov; 74(3):386-92. PubMed ID: 14598315
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production.
    Citron M; Oltersdorf T; Haass C; McConlogue L; Hung AY; Seubert P; Vigo-Pelfrey C; Lieberburg I; Selkoe DJ
    Nature; 1992 Dec; 360(6405):672-4. PubMed ID: 1465129
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The cytosolic domain of APP and its possible role in the pathogenesis of Alzheimer's disease.
    Minopoli G; Zambrano N; Russo T
    Ital J Biochem; 2006; 55(3-4):205-11. PubMed ID: 17274526
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Demonstration by FRET of BACE interaction with the amyloid precursor protein at the cell surface and in early endosomes.
    Kinoshita A; Fukumoto H; Shah T; Whelan CM; Irizarry MC; Hyman BT
    J Cell Sci; 2003 Aug; 116(Pt 16):3339-46. PubMed ID: 12829747
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.