BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

139 related articles for article (PubMed ID: 7983030)

  • 1. Identification of peptide binding residues in the extracellular domains of the AT1 receptor.
    Hjorth SA; Schambye HT; Greenlee WJ; Schwartz TW
    J Biol Chem; 1994 Dec; 269(49):30953-9. PubMed ID: 7983030
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Differential structural requirements for specific binding of nonpeptide and peptide antagonists to the AT1 angiotensin receptor. Identification of amino acid residues that determine binding of the antihypertensive drug losartan.
    Ji H; Leung M; Zhang Y; Catt KJ; Sandberg K
    J Biol Chem; 1994 Jun; 269(24):16533-6. PubMed ID: 8206967
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Differentiation between binding sites for angiotensin II and nonpeptide antagonists on the angiotensin II type 1 receptors.
    Schambye HT; Hjorth SA; Bergsma DJ; Sathe G; Schwartz TW
    Proc Natl Acad Sci U S A; 1994 Jul; 91(15):7046-50. PubMed ID: 8041743
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Interaction between the nonpeptide angiotensin antagonist SKF-108,566 and histidine 256 (HisVI:16) of the angiotensin type 1 receptor.
    Schambye HT; Hjorth SA; Weinstock J; Schwartz TW
    Mol Pharmacol; 1995 Mar; 47(3):425-31. PubMed ID: 7700239
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The conformational change responsible for AT1 receptor activation is dependent upon two juxtaposed asparagine residues on transmembrane helices III and VII.
    Balmforth AJ; Lee AJ; Warburton P; Donnelly D; Ball SG
    J Biol Chem; 1997 Feb; 272(7):4245-51. PubMed ID: 9020140
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Dependence of AT1 angiotensin receptor function on adjacent asparagine residues in the seventh transmembrane helix.
    Hunyady L; Ji H; Jagadeesh G; Zhang M; Gáborik Z; Mihalik B; Catt KJ
    Mol Pharmacol; 1998 Aug; 54(2):427-34. PubMed ID: 9687585
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Relevant role of Leu265 in helix VI of the angiotensin AT1 receptor in agonist binding and activity.
    Correa SA; França LP; Costa-Neto CM; Oliveira L; Paiva AC; Shimuta SI
    Can J Physiol Pharmacol; 2002 May; 80(5):426-30. PubMed ID: 12056549
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genetic transfer of a nonpeptide antagonist binding site to a previously unresponsive angiotensin receptor.
    Ji H; Zheng W; Zhang Y; Catt KJ; Sandberg K
    Proc Natl Acad Sci U S A; 1995 Sep; 92(20):9240-4. PubMed ID: 7568109
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenesis and the molecular modeling of the rat angiotensin II receptor (AT1).
    Yamano Y; Ohyama K; Kikyo M; Sano T; Nakagomi Y; Inoue Y; Nakamura N; Morishima I; Guo DF; Hamakubo T
    J Biol Chem; 1995 Jun; 270(23):14024-30. PubMed ID: 7775462
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Non-peptide angiotensin agonist. Functional and molecular interaction with the AT1 receptor.
    Perlman S; Schambye HT; Rivero RA; Greenlee WJ; Hjorth SA; Schwartz TW
    J Biol Chem; 1995 Jan; 270(4):1493-6. PubMed ID: 7829475
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Dependence of agonist activation on a conserved apolar residue in the third intracellular loop of the AT1 angiotensin receptor.
    Hunyady L; Zhang M; Jagadeesh G; Bor M; Balla T; Catt KJ
    Proc Natl Acad Sci U S A; 1996 Sep; 93(19):10040-5. PubMed ID: 8816747
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Polar residues in the transmembrane domains of the type 1 angiotensin II receptor are required for binding and coupling. Reconstitution of the binding site by co-expression of two deficient mutants.
    Monnot C; Bihoreau C; Conchon S; Curnow KM; Corvol P; Clauser E
    J Biol Chem; 1996 Jan; 271(3):1507-13. PubMed ID: 8576145
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The ligand binding site of the angiotensin AT1 receptor.
    Hunyady L; Balla T; Catt KJ
    Trends Pharmacol Sci; 1996 Apr; 17(4):135-40. PubMed ID: 8984739
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor.
    Holst B; Zoffmann S; Elling CE; Hjorth SA; Schwartz TW
    Mol Pharmacol; 1998 Jan; 53(1):166-75. PubMed ID: 9443945
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of critical extracellular loop residues involved in alpha 1-adrenergic receptor subtype-selective antagonist binding.
    Zhao MM; Hwa J; Perez DM
    Mol Pharmacol; 1996 Nov; 50(5):1118-26. PubMed ID: 8913343
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in transmembrane segment VII of the AT1 receptor differentiate between closely related insurmountable and competitive angiotensin antagonists.
    Schambye HT; von Wijk B; Hjorth SA; Wienen W; Entzeroth M; Bergsma DJ; Schwartz TW
    Br J Pharmacol; 1994 Oct; 113(2):331-3. PubMed ID: 7834178
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mutational analysis of the angiotensin type 2 receptor: contribution of conserved amino acids in the region of the sixth transmembrane domain.
    Heerding JN; Yee DK; Krichavsky MZ; Fluharty SJ
    Regul Pept; 1998 Jun; 74(2-3):113-9. PubMed ID: 9712171
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The species selectivity of chemically distinct tachykinin nonpeptide antagonists is dependent on common divergent residues of the rat and human neurokinin-1 receptors.
    Jensen CJ; Gerard NP; Schwartz TW; Gether U
    Mol Pharmacol; 1994 Feb; 45(2):294-9. PubMed ID: 7509441
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of Lys215 located in the fifth transmembrane domain of the AT2 receptor in ligand-receptor interaction.
    Pulakat L; Tadessee AS; Dittus JJ; Gavini N
    Regul Pept; 1998 Jan; 73(1):51-7. PubMed ID: 9537673
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutations along transmembrane segment II of the NK-1 receptor affect substance P competition with non-peptide antagonists but not substance P binding.
    Rosenkilde MM; Cahir M; Gether U; Hjorth SA; Schwartz TW
    J Biol Chem; 1994 Nov; 269(45):28160-4. PubMed ID: 7525569
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.