BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 7994033)

  • 1. Identification of a novel thrombin receptor sequence required for activation-dependent responses.
    Bahou WF; Kutok JL; Wong A; Potter CL; Coller BS
    Blood; 1994 Dec; 84(12):4195-202. PubMed ID: 7994033
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The thrombin receptor extracellular domain contains sites crucial for peptide ligand-induced activation.
    Bahou WF; Coller BS; Potter CL; Norton KJ; Kutok JL; Goligorsky MS
    J Clin Invest; 1993 Apr; 91(4):1405-13. PubMed ID: 8386186
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Immunologic analysis of the cloned platelet thrombin receptor activation mechanism: evidence supporting receptor cleavage, release of the N-terminal peptide, and insertion of the tethered ligand into a protected environment.
    Norton KJ; Scarborough RM; Kutok JL; Escobedo MA; Nannizzi L; Coller BS
    Blood; 1993 Oct; 82(7):2125-36. PubMed ID: 8400262
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Thrombin receptor activation. Confirmation of the intramolecular tethered liganding hypothesis and discovery of an alternative intermolecular liganding mode.
    Chen J; Ishii M; Wang L; Ishii K; Coughlin SR
    J Biol Chem; 1994 Jun; 269(23):16041-5. PubMed ID: 8206902
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Extracellular mutations of protease-activated receptor-1 result in differential activation by thrombin and thrombin receptor agonist peptide.
    Blackhart BD; Ruslim-Litrus L; Lu CC; Alves VL; Teng W; Scarborough RM; Reynolds EE; Oksenberg D
    Mol Pharmacol; 2000 Dec; 58(6):1178-87. PubMed ID: 11093752
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation.
    Vu TK; Hung DT; Wheaton VI; Coughlin SR
    Cell; 1991 Mar; 64(6):1057-68. PubMed ID: 1672265
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The cleaved peptide of the thrombin receptor is a strong platelet agonist.
    Furman MI; Liu L; Benoit SE; Becker RC; Barnard MR; Michelson AD
    Proc Natl Acad Sci U S A; 1998 Mar; 95(6):3082-7. PubMed ID: 9501219
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Tethered ligand agonist peptides. Structural requirements for thrombin receptor activation reveal mechanism of proteolytic unmasking of agonist function.
    Scarborough RM; Naughton MA; Teng W; Hung DT; Rose J; Vu TK; Wheaton VI; Turck CW; Coughlin SR
    J Biol Chem; 1992 Jul; 267(19):13146-9. PubMed ID: 1320011
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The proteinase activated receptor-2 (PAR-2) mediates mitogenic responses in human vascular endothelial cells.
    Mirza H; Yatsula V; Bahou WF
    J Clin Invest; 1996 Apr; 97(7):1705-14. PubMed ID: 8601636
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Specific inhibition of thrombin-induced cell activation by the neutrophil proteinases elastase, cathepsin G, and proteinase 3: evidence for distinct cleavage sites within the aminoterminal domain of the thrombin receptor.
    Renesto P; Si-Tahar M; Moniatte M; Balloy V; Van Dorsselaer A; Pidard D; Chignard M
    Blood; 1997 Mar; 89(6):1944-53. PubMed ID: 9058715
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Plasmin-platelet interaction involves cleavage of functional thrombin receptor.
    Kimura M; Andersen TT; Fenton JW; Bahou WF; Aviv A
    Am J Physiol; 1996 Jul; 271(1 Pt 1):C54-60. PubMed ID: 8760030
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Proteolysis of the human platelet and endothelial cell thrombin receptor by neutrophil-derived cathepsin G.
    Molino M; Blanchard N; Belmonte E; Tarver AP; Abrams C; Hoxie JA; Cerletti C; Brass LF
    J Biol Chem; 1995 May; 270(19):11168-75. PubMed ID: 7744748
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Tethered ligand library for discovery of peptide agonists.
    Chen J; Bernstein HS; Chen M; Wang L; Ishii M; Turck CW; Coughlin SR
    J Biol Chem; 1995 Oct; 270(40):23398-401. PubMed ID: 7559498
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Site-specific thrombin receptor antibodies inhibit Ca2+ signaling and increased endothelial permeability.
    Nguyen LT; Lum H; Tiruppathì C; Malik AB
    Am J Physiol; 1997 Nov; 273(5):C1756-63. PubMed ID: 9374664
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Binding of thrombin to the G-protein-linked receptor, and not to glycoprotein Ib, precedes thrombin-mediated platelet activation.
    Liu L; Freedman J; Hornstein A; Fenton JW; Song Y; Ofosu FA
    J Biol Chem; 1997 Jan; 272(3):1997-2004. PubMed ID: 8999892
    [TBL] [Abstract][Full Text] [Related]  

  • 16. 'Tethered ligand' derived pentapeptide agonists of thrombin receptor: a study of side chain requirements for human platelet activation and GTPase stimulation.
    Natarajan S; Riexinger D; Peluso M; Seiler SM
    Int J Pept Protein Res; 1995 Feb; 45(2):145-51. PubMed ID: 7782162
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Agonist recognition by proteinase-activated receptor 2 and thrombin receptor. Importance of extracellular loop interactions for receptor function.
    Lerner DJ; Chen M; Tram T; Coughlin SR
    J Biol Chem; 1996 Jun; 271(24):13943-7. PubMed ID: 8662993
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Synthetic alpha-thrombin receptor peptides activate G protein-coupled signaling pathways but are unable to induce mitogenesis.
    Vouret-Craviari V; Van Obberghen-Schilling E; Rasmussen UB; Pavirani A; Lecocq JP; Pouysségur J
    Mol Biol Cell; 1992 Jan; 3(1):95-102. PubMed ID: 1312881
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specificity of the thrombin receptor for agonist peptide is defined by its extracellular surface.
    Gerszten RE; Chen J; Ishii M; Ishii K; Wang L; Nanevicz T; Turck CW; Vu TK; Coughlin SR
    Nature; 1994 Apr; 368(6472):648-51. PubMed ID: 8145852
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure-activity analysis of synthetic alpha-thrombin-receptor-activating peptides.
    Van Obberghen-Schilling E; Rasmussen UB; Vouret-Craviari V; Lentes KU; Pavirani A; Pouysségur J
    Biochem J; 1993 Jun; 292 ( Pt 3)(Pt 3):667-71. PubMed ID: 7686363
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.