These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

138 related articles for article (PubMed ID: 7996544)

  • 41. Synthesis of a novel C2/C2'-aryl-substituted pyrrolo[2,1-c][1,4]benzodiazepine dimer prodrug with improved water solubility and reduced DNA reaction rate.
    Howard PW; Chen Z; Gregson SJ; Masterson LA; Tiberghien AC; Cooper N; Fang M; Coffils MJ; Klee S; Hartley JA; Thurston DE
    Bioorg Med Chem Lett; 2009 Nov; 19(22):6463-6. PubMed ID: 19811912
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Pyrrolopyrimidine nucleosides. 18. Synthesis and chemotherapeutic activity of 4-amino-7-(3-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d] pyrimidine-5-carboxamide (3'-deoxysangivamycin) and 4-amino-7-(2-deoxy-beta-D-ribofuranosyl)pyrrolo[2,3-d] pyrimidine-5-carboxamide (2'-deoxysangivamycin).
    Maruyama T; Wotring LL; Townsend LB
    J Med Chem; 1983 Jan; 26(1):25-9. PubMed ID: 6827526
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Synthesis and antitumor activity of isodoxorubicin analogues.
    Florent JC; Gaudel G; Monneret C; Hoffmann D; Kraemer HP
    J Med Chem; 1993 May; 36(10):1364-8. PubMed ID: 8496904
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Design, synthesis, and biological evaluation of combretabenzodiazepines: a novel class of anti-tubulin agents.
    Galli U; Travelli C; Aprile S; Arrigoni E; Torretta S; Grosa G; Massarotti A; Sorba G; Canonico PL; Genazzani AA; Tron GC
    J Med Chem; 2015 Feb; 58(3):1345-57. PubMed ID: 25584687
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Bicyclic and tricyclic analogues of anthramycin.
    Kaneko T; Wong H; Doyle TW; Rose WC; Bradner WT
    J Med Chem; 1985 Mar; 28(3):388-92. PubMed ID: 3973905
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Adriamycin analogues. Novel anomeric ribofuranoside analogues of daunorubicin.
    Israel M; Airey JE; Murray RJ; Gillard JW
    J Med Chem; 1982 Jan; 25(1):28-31. PubMed ID: 7086818
    [TBL] [Abstract][Full Text] [Related]  

  • 47. Application of the Stille coupling reaction to the synthesis of C2-substituted endo-exo unsaturated pyrrolo[2,1-c][1,4]benzodiazepines (PBDs).
    Tiberghien AC; Hagan D; Howard PW; Thurston DE
    Bioorg Med Chem Lett; 2004 Oct; 14(20):5041-4. PubMed ID: 15380195
    [TBL] [Abstract][Full Text] [Related]  

  • 48. New pyrrolobenzodiazepine antibiotics, RK-1441A and B. I. Biological properties.
    Osada H; Ishinabe K; Yano T; Kajikawa K; Isono K
    Agric Biol Chem; 1990 Nov; 54(11):2875-81. PubMed ID: 1369312
    [TBL] [Abstract][Full Text] [Related]  

  • 49. Novel pyrazole derivatives as anticancer and radiosensitizing agents.
    Aly HM; El-Gazzar MG
    Arzneimittelforschung; 2012 Mar; 62(3):105-12. PubMed ID: 22407898
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Lipophilic analogues of sparsomycin as strong inhibitors of protein synthesis and tumor growth: a structure-activity relationship study.
    van den Broek LA; Lázaro E; Zylicz Z; Fennis PJ; Missler FA; Lelieveld P; Garzotto M; Wagener DJ; Ballesta JP; Ottenheijm HC
    J Med Chem; 1989 Aug; 32(8):2002-15. PubMed ID: 2754719
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Benzimidazo[1,2-c]quinazolines: a new class of antitumor compounds.
    Braña MF; Castellano JM; Keilhauer G; Machuca A; Martín Y; Redondo C; Schlick E; Walker N
    Anticancer Drug Des; 1994 Dec; 9(6):527-38. PubMed ID: 7880377
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Design and synthesis of pyrrolobenzodiazepine-gallic hybrid agents as p53-dependent and -independent apoptogenic signaling in melanoma cells.
    Chou YW; Senadi GC; Chen CY; Kuo KK; Lin YT; Wang JJ; Lee JH; Wang YC; Hu WP
    Eur J Med Chem; 2016 Feb; 109():59-74. PubMed ID: 26756315
    [TBL] [Abstract][Full Text] [Related]  

  • 53. Preclinical pharmacology and antitumour activity of the novel sequence-selective DNA minor-groove cross-linking agent DSB-120.
    Walton MI; Goddard P; Kelland LR; Thurston DE; Harrap KR
    Cancer Chemother Pharmacol; 1996; 38(5):431-8. PubMed ID: 8765436
    [TBL] [Abstract][Full Text] [Related]  

  • 54. Synthesis and biological activity of pyrimidobenzodiazepine derivatives. New ring systems: triazolo- and tetrazolo-pyrimido-benzodiazepines.
    Długosz A
    Pharmazie; 1995 Mar; 50(3):180-2. PubMed ID: 7732047
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Synthesis, anticancer evaluation, and molecular docking studies of some novel 4,6-disubstituted pyrazolo[3,4-d]pyrimidines as cyclin-dependent kinase 2 (CDK2) inhibitors.
    Cherukupalli S; Chandrasekaran B; Kryštof V; Aleti RR; Sayyad N; Merugu SR; Kushwaha ND; Karpoormath R
    Bioorg Chem; 2018 Sep; 79():46-59. PubMed ID: 29753773
    [TBL] [Abstract][Full Text] [Related]  

  • 56. Solid-phase synthesis of a library of pyrrolo[2,1-c][1,4]benzodiazepine-5,11-diones with potential antitubercular activity.
    Kamal A; Reddy KL; Devaiah V; Shankaraiah N; Reddy GS; Raghavan S
    J Comb Chem; 2007; 9(1):29-42. PubMed ID: 17206830
    [TBL] [Abstract][Full Text] [Related]  

  • 57. SG2285, a novel C2-aryl-substituted pyrrolobenzodiazepine dimer prodrug that cross-links DNA and exerts highly potent antitumor activity.
    Hartley JA; Hamaguchi A; Coffils M; Martin CR; Suggitt M; Chen Z; Gregson SJ; Masterson LA; Tiberghien AC; Hartley JM; Pepper C; Lin TT; Fegan C; Thurston DE; Howard PW
    Cancer Res; 2010 Sep; 70(17):6849-58. PubMed ID: 20660714
    [TBL] [Abstract][Full Text] [Related]  

  • 58. Synthesis and kinase inhibitory activity of new sulfonamide derivatives of pyrazolo[4,3-e][1,2,4]triazines.
    Mojzych M; Šubertová V; Bielawska A; Bielawski K; Bazgier V; Berka K; Gucký T; Fornal E; Kryštof V
    Eur J Med Chem; 2014 May; 78():217-24. PubMed ID: 24681986
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Design, synthesis and in vitro cytotoxic studies of novel bis-pyrrolo[2,1][1,4] benzodiazepine-pyrrole and imidazole polyamide conjugates.
    Kumar R; Lown JW
    Eur J Med Chem; 2005 Jul; 40(7):641-54. PubMed ID: 15935899
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Synthesis and antitumor properties of pyrazolo [3,4-D] pyrimidine derivatives.
    Witkiewicz K; Machoń Z; Mordarski M; Wieczorek J
    Pol J Pharmacol Pharm; 1987; 39(6):715-20. PubMed ID: 3503990
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.