141 related articles for article (PubMed ID: 8012276)
1. bis(2,6-dioxopiperaxine) derivatives, topoisomerase II inhibitors which do not form a DNA cleavable complex, induce thymocyte apoptosis.
Onishi Y; Azuma Y; Kizaki H
Biochem Mol Biol Int; 1994 Jan; 32(1):115-22. PubMed ID: 8012276
[TBL] [Abstract][Full Text] [Related]
2. Inhibition of topoisomerase II by antitumor agents bis(2,6-dioxopiperazine) derivatives.
Tanabe K; Ikegami Y; Ishida R; Andoh T
Cancer Res; 1991 Sep; 51(18):4903-8. PubMed ID: 1654204
[TBL] [Abstract][Full Text] [Related]
3. Topoisomerase II inhibitor-induced apoptosis in thymocytes and lymphoma cells.
Kizaki H; Onishi Y
Adv Enzyme Regul; 1997; 37():403-23. PubMed ID: 9381984
[TBL] [Abstract][Full Text] [Related]
4. Inhibition of intracellular topoisomerase II by antitumor bis(2,6-dioxopiperazine) derivatives: mode of cell growth inhibition distinct from that of cleavable complex-forming type inhibitors.
Ishida R; Miki T; Narita T; Yui R; Sato M; Utsumi KR; Tanabe K; Andoh T
Cancer Res; 1991 Sep; 51(18):4909-16. PubMed ID: 1654205
[TBL] [Abstract][Full Text] [Related]
5. Selective inhibition of topoisomerase II by ICRF-193 does not support a role for topoisomerase II activity in the fragmentation of chromatin during apoptosis of human leukemia cells.
Beere HM; Chresta CM; Hickman JA
Mol Pharmacol; 1996 May; 49(5):842-51. PubMed ID: 8622634
[TBL] [Abstract][Full Text] [Related]
6. Contribution of gene-specific lesions, DNA-replication-associated damage, and subsequent transcriptional inhibition in topoisomerase inhibitor-mediated apoptosis in lymphoma cells.
Muscarella DE; Rachlinski MK; Sotiriadis J; Bloom SE
Exp Cell Res; 1998 Jan; 238(1):155-67. PubMed ID: 9457068
[TBL] [Abstract][Full Text] [Related]
7. The mechanism of epipodophyllotoxin-induced thymocyte apoptosis: possible role of a novel Ca(2+)-independent protein kinase.
Ye X; Georgoff I; Fleisher S; Coffman FD; Cohen S; Fresa KL
Cell Immunol; 1993 Oct; 151(2):320-35. PubMed ID: 8402939
[TBL] [Abstract][Full Text] [Related]
8. Selection of human leukemic CEM cells for resistance to the DNA topoisomerase II catalytic inhibitor ICRF-187 results in increased levels of topoisomerase IIalpha and altered G(2)/M checkpoint and apoptotic responses.
Morgan SE; Cadena RS; Raimondi SC; Beck WT
Mol Pharmacol; 2000 Feb; 57(2):296-307. PubMed ID: 10648639
[TBL] [Abstract][Full Text] [Related]
9. Chinese hamster ovary cells resistant to the topoisomerase II catalytic inhibitor ICRF-159: a Tyr49Phe mutation confers high-level resistance to bisdioxopiperazines.
Sehested M; Wessel I; Jensen LH; Holm B; Oliveri RS; Kenwrick S; Creighton AM; Nitiss JL; Jensen PB
Cancer Res; 1998 Apr; 58(7):1460-8. PubMed ID: 9537249
[TBL] [Abstract][Full Text] [Related]
10. Apoptosis induced by anthracycline antibiotics in P388 parent and multidrug-resistant cells.
Ling YH; Priebe W; Perez-Soler R
Cancer Res; 1993 Apr; 53(8):1845-52. PubMed ID: 8467504
[TBL] [Abstract][Full Text] [Related]
11. Differential cytotoxic pathways of topoisomerase I and II anticancer agents after overexpression of the E2F-1/DP-1 transcription factor complex.
Hofland K; Petersen BO; Falck J; Helin K; Jensen PB; Sehested M
Clin Cancer Res; 2000 Apr; 6(4):1488-97. PubMed ID: 10778981
[TBL] [Abstract][Full Text] [Related]
12. DNA topoisomerase II is the molecular target of bisdioxopiperazine derivatives ICRF-159 and ICRF-193 in Saccharomyces cerevisiae.
Ishida R; Hamatake M; Wasserman RA; Nitiss JL; Wang JC; Andoh T
Cancer Res; 1995 Jun; 55(11):2299-303. PubMed ID: 7757979
[TBL] [Abstract][Full Text] [Related]
13. Topoisomerase II-reactive chemotherapeutic drugs induce apoptosis in thymocytes.
Walker PR; Smith C; Youdale T; Leblanc J; Whitfield JF; Sikorska M
Cancer Res; 1991 Feb; 51(4):1078-85. PubMed ID: 1847655
[TBL] [Abstract][Full Text] [Related]
14. Topoisomerase inhibitor camptothecin sensitizes mouse hepatocytes in vitro and in vivo to TNF-mediated apoptosis.
Hentze H; Latta M; Künstle G; Dhakshinamoorthy S; Ng PY; Porter AG; Wendel A
Hepatology; 2004 May; 39(5):1311-20. PubMed ID: 15122760
[TBL] [Abstract][Full Text] [Related]
15. Programmed cell death (apoptosis) of mouse fibroblasts is induced by the topoisomerase II inhibitor etoposide.
Mizumoto K; Rothman RJ; Farber JL
Mol Pharmacol; 1994 Nov; 46(5):890-5. PubMed ID: 7969076
[TBL] [Abstract][Full Text] [Related]
16. Selective inhibition of dexamethasone-induced apoptosis in rat thymocytes by herbimycin A.
Lee E; Miura M; Yoshinari M; Iwai H; Kariya K
Biochem Biophys Res Commun; 1994 Jul; 202(1):128-34. PubMed ID: 8037703
[TBL] [Abstract][Full Text] [Related]
17. Biphasic effect of staurosporine on thymocyte apoptosis.
Suzuki K; Azuma Y; Onishi Y; Kizaki H; Ishimura Y
Biochem Mol Biol Int; 1995 Apr; 35(5):1085-92. PubMed ID: 7549927
[TBL] [Abstract][Full Text] [Related]
18. Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cells.
Jensen LH; Dejligbjerg M; Hansen LT; Grauslund M; Jensen PB; Sehested M
BMC Pharmacol; 2004 Dec; 4():31. PubMed ID: 15575955
[TBL] [Abstract][Full Text] [Related]
19. Differential sensitivity to the induction of apoptosis by cisplatin in proliferating and quiescent immature rat thymocytes is independent of the levels of drug accumulation and DNA adduct formation.
Evans DL; Tilby M; Dive C
Cancer Res; 1994 Mar; 54(6):1596-603. PubMed ID: 8137265
[TBL] [Abstract][Full Text] [Related]
20. [Poisons of DNA topoisomerases I and II].
Charcosset JY; Soues S; Laval F
Bull Cancer; 1993 Nov; 80(11):923-54. PubMed ID: 8081034
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]