BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

213 related articles for article (PubMed ID: 8013282)

  • 1. The polymorphic cytochrome P-4502D6 is involved in the metabolism of both 5-hydroxytryptamine antagonists, tropisetron and ondansetron.
    Fischer V; Vickers AE; Heitz F; Mahadevan S; Baldeck JP; Minery P; Tynes R
    Drug Metab Dispos; 1994; 22(2):269-74. PubMed ID: 8013282
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Characterization of the cytochrome P450 enzymes involved in the in vitro metabolism of dolasetron. Comparison with other indole-containing 5-HT3 antagonists.
    Sanwald P; David M; Dow J
    Drug Metab Dispos; 1996 May; 24(5):602-9. PubMed ID: 8723743
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Oxidation of histamine H1 antagonist mequitazine is catalyzed by cytochrome P450 2D6 in human liver microsomes.
    Nakamura K; Yokoi T; Kodama T; Inoue K; Nagashima K; Shimada N; Shimizu T; Kamataki T
    J Pharmacol Exp Ther; 1998 Feb; 284(2):437-42. PubMed ID: 9454781
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitory effects of azelastine and its metabolites on drug oxidation catalyzed by human cytochrome P-450 enzymes.
    Nakajima M; Ohyama K; Nakamura S; Shimada N; Yamazaki H; Yokoi T
    Drug Metab Dispos; 1999 Jul; 27(7):792-7. PubMed ID: 10383922
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple forms of cytochrome P450 are involved in the metabolism of ondansetron in humans.
    Dixon CM; Colthup PV; Serabjit-Singh CJ; Kerr BM; Boehlert CC; Park GR; Tarbit MH
    Drug Metab Dispos; 1995 Nov; 23(11):1225-30. PubMed ID: 8591723
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Human liver cytochrome P4503A biotransformation of the cyclosporin derivative SDZ IMM 125.
    Vickers AE; Meyer E; Dannecker R; Keller B; Tynes RE; Maurer G
    Drug Metab Dispos; 1995 Mar; 23(3):321-6. PubMed ID: 7628296
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Identification of human cytochrome P450 isoforms involved in the 3-hydroxylation of quinine by human live microsomes and nine recombinant human cytochromes P450.
    Zhao XJ; Yokoyama H; Chiba K; Wanwimolruk S; Ishizaki T
    J Pharmacol Exp Ther; 1996 Dec; 279(3):1327-34. PubMed ID: 8968357
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Interaction of terfenadine and its primary metabolites with cytochrome P450 2D6.
    Jones BC; Hyland R; Ackland M; Tyman CA; Smith DA
    Drug Metab Dispos; 1998 Sep; 26(9):875-82. PubMed ID: 9733666
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Identification of human cytochrome P450 isoforms involved in the stereoselective metabolism of mianserin enantiomers.
    Koyama E; Chiba K; Tani M; Ishizaki T
    J Pharmacol Exp Ther; 1996 Jul; 278(1):21-30. PubMed ID: 8764331
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reappraisal of human CYP isoforms involved in imipramine N-demethylation and 2-hydroxylation: a study using microsomes obtained from putative extensive and poor metabolizers of S-mephenytoin and eleven recombinant human CYPs.
    Koyama E; Chiba K; Tani M; Ishizaki T
    J Pharmacol Exp Ther; 1997 Jun; 281(3):1199-210. PubMed ID: 9190854
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of antidepressant drugs on the activity of cytochrome P-450 measured by caffeine oxidation in rat liver microsomes.
    Danie WA; Syrek M; Ryłko Z; Wójcikowski J
    Pol J Pharmacol; 2001; 53(4):351-7. PubMed ID: 11990081
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of methoxyphenamine in vitro by a CYP2D6 microsomal preparation.
    Coutts RT; Bolaji OO; Su P; Baker GB
    Drug Metab Dispos; 1994; 22(5):756-60. PubMed ID: 7835228
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Timolol metabolism in human liver microsomes is mediated principally by CYP2D6.
    Volotinen M; Turpeinen M; Tolonen A; Uusitalo J; Mäenpää J; Pelkonen O
    Drug Metab Dispos; 2007 Jul; 35(7):1135-41. PubMed ID: 17431033
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolic kinetics of pseudoracemic propranolol in human liver microsomes. Enantioselectivity and quinidine inhibition.
    Marathe PH; Shen DD; Nelson WL
    Drug Metab Dispos; 1994; 22(2):237-47. PubMed ID: 8013280
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Characterisation of the cytochrome P450 enzymes involved in the in vitro metabolism of granisetron.
    Bloomer JC; Baldwin SJ; Smith GJ; Ayrton AD; Clarke SE; Chenery RJ
    Br J Clin Pharmacol; 1994 Dec; 38(6):557-66. PubMed ID: 7888294
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibition of debrisoquin clearance in perfused rat livers and inhibition of dextromethorphan metabolism in human liver microsomes by 4-hydroxydebrisoquin or other metabolites of debrisoquin.
    Jaruratanasirikul S; Cooper AD; Blaschke TF
    Drug Metab Dispos; 1992; 20(3):379-82. PubMed ID: 1355711
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The role of CYP2C19 in the metabolism of (+/-) bufuralol, the prototypic substrate of CYP2D6.
    Mankowski DC
    Drug Metab Dispos; 1999 Sep; 27(9):1024-8. PubMed ID: 10460802
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Budesonide is metabolized by cytochrome P450 3A (CYP3A) enzymes in human liver.
    Jönsson G; Aström A; Andersson P
    Drug Metab Dispos; 1995 Jan; 23(1):137-42. PubMed ID: 7720517
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Characterization of metabolites and human P450 isoforms involved in the microsomal metabolism of mesaconitine.
    Ye L; Tang L; Gong Y; Lv C; Zheng Z; Jiang Z; Liu Z
    Xenobiotica; 2011 Jan; 41(1):46-58. PubMed ID: 21105783
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.