These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

185 related articles for article (PubMed ID: 8031773)

  • 1. Activation of human O6-alkylguanine-DNA alkyltransferase by DNA.
    Goodtzova K; Crone TM; Pegg AE
    Biochemistry; 1994 Jul; 33(28):8385-90. PubMed ID: 8031773
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mechanism of inactivation of human O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine.
    Pegg AE; Boosalis M; Samson L; Moschel RC; Byers TL; Swenn K; Dolan ME
    Biochemistry; 1993 Nov; 32(45):11998-2006. PubMed ID: 8218276
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A single amino acid change in human O6-alkylguanine-DNA alkyltransferase decreasing sensitivity to inactivation by O6-benzylguanine.
    Crone TM; Pegg AE
    Cancer Res; 1993 Oct; 53(20):4750-3. PubMed ID: 8402653
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Comparison of the inactivation of mammalian and bacterial O6-alkylguanine-DNA alkyltransferases by O6-benzylguanine and O6-methylguanine.
    Dolan ME; Pegg AE; Dumenco LL; Moschel RC; Gerson SL
    Carcinogenesis; 1991 Dec; 12(12):2305-9. PubMed ID: 1747932
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Resistance of the human O6-alkylguanine-DNA alkyltransferase containing arginine at codon 160 to inactivation by O6-benzylguanine.
    Edara S; Kanugula S; Goodtzova K; Pegg AE
    Cancer Res; 1996 Dec; 56(24):5571-5. PubMed ID: 8971155
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effect of DNA on the inactivation of O6-alkylguanine-DNA alkyltransferase by 9-substituted O6-benzylguanine derivatives.
    Pegg AE; Chung L; Moschel RC
    Biochem Pharmacol; 1997 May; 53(10):1559-64. PubMed ID: 9260884
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alteration of arginine-128 to alanine abolishes the ability of human O6-alkylguanine-DNA alkyltransferase to repair methylated DNA but has no effect on its reaction with O6-benzylguanine.
    Kanugula S; Goodtzova K; Edara S; Pegg AE
    Biochemistry; 1995 May; 34(21):7113-9. PubMed ID: 7766621
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutations in human O6-alkylguanine-DNA alkyltransferase imparting resistance to O6-benzylguanine.
    Crone TM; Goodtzova K; Edara S; Pegg AE
    Cancer Res; 1994 Dec; 54(23):6221-7. PubMed ID: 7954470
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Reaction of O6-benzylguanine-resistant mutants of human O6-alkylguanine-DNA alkyltransferase with O6-benzylguanine in oligodeoxyribonucleotides.
    Pegg AE; Kanugula S; Edara S; Pauly GT; Moschel RC; Goodtzova K
    J Biol Chem; 1998 May; 273(18):10863-7. PubMed ID: 9556560
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Repair of O6-benzylguanine by the Escherichia coli Ada and Ogt and the human O6-alkylguanine-DNA alkyltransferases.
    Goodtzova K; Kanugula S; Edara S; Pauly GT; Moschel RC; Pegg AE
    J Biol Chem; 1997 Mar; 272(13):8332-9. PubMed ID: 9079656
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Reduction of O6-alkylguanine-DNA alkyltransferase activity in HeLa cells treated with O6-alkylguanines.
    Dolan ME; Morimoto K; Pegg AE
    Cancer Res; 1985 Dec; 45(12 Pt 1):6413-7. PubMed ID: 4063990
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Depletion of O6-alkylguanine-DNA alkyltransferase by O6-benzylguanine in three-dimensional collagen cultures of normal human breast epithelial cells.
    Hamdan MA; Guzman RC; Yang J; Beattie C; Mascharack P; Nandi S
    Carcinogenesis; 1992 Oct; 13(10):1743-9. PubMed ID: 1423833
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Metabolism of O6-benzylguanine, an inactivator of O6-alkylguanine-DNA alkyltransferase.
    Dolan ME; Chae MY; Pegg AE; Mullen JH; Friedman HS; Moschel RC
    Cancer Res; 1994 Oct; 54(19):5123-30. PubMed ID: 7923129
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Depletion of mammalian O6-alkylguanine-DNA alkyltransferase activity by O6-benzylguanine provides a means to evaluate the role of this protein in protection against carcinogenic and therapeutic alkylating agents.
    Dolan ME; Moschel RC; Pegg AE
    Proc Natl Acad Sci U S A; 1990 Jul; 87(14):5368-72. PubMed ID: 2164681
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Binding and repair of O6-ethylguanine in double-stranded oligodeoxynucleotides by recombinant human O6-alkylguanine-DNA alkyltransferase do not exhibit significant dependence on sequence context.
    Bender K; Federwisch M; Loggen U; Nehls P; Rajewsky MF
    Nucleic Acids Res; 1996 Jun; 24(11):2087-94. PubMed ID: 8668540
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Mutations in the Ada O6-alkylguanine-DNA alkyltransferase conferring sensitivity to inactivation by O6-benzylguanine and 2,4-diamino-6-benzyloxy-5-nitrosopyrimidine.
    Crone TM; Kanugula S; Pegg AE
    Carcinogenesis; 1995 Aug; 16(8):1687-92. PubMed ID: 7634390
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Specific labeling of O6-alkylguanine-DNA alkyltransferase by reaction with O6-(p-hydroxy[3H]methylbenzyl)guanine.
    Ciocco GM; Moschel RC; Chae MY; McLaughlin PJ; Zagon IS; Pegg AE
    Cancer Res; 1995 Sep; 55(18):4085-91. PubMed ID: 7664284
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inactivation of O(6)-alkylguanine-DNA alkyltransferase by folate esters of O(6)-benzyl-2'-deoxyguanosine and of O(6)-[4-(hydroxymethyl)benzyl]guanine.
    Javanmard S; Loktionova NA; Fang Q; Pauly GT; Pegg AE; Moschel RC
    J Med Chem; 2007 Oct; 50(21):5193-201. PubMed ID: 17880193
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specificity of O6-alkylguanine-DNA alkyltransferase.
    Pegg AE; Scicchitano D; Morimoto K; Dolan ME
    IARC Sci Publ; 1987; (84):30-4. PubMed ID: 3679391
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Modulation of mammalian O6-alkylguanine-DNA alkyltransferase in vivo by O6-benzylguanine and its effect on the sensitivity of a human glioma tumor to 1-(2-chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea.
    Dolan ME; Stine L; Mitchell RB; Moschel RC; Pegg AE
    Cancer Commun; 1990; 2(11):371-7. PubMed ID: 2242301
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.