232 related articles for article (PubMed ID: 8043197)
1. The role of 12 cDNA-expressed human, rodent, and rabbit cytochromes P450 in the metabolism of benzo[a]pyrene and benzo[a]pyrene trans-7,8-dihydrodiol.
Shou M; Korzekwa KR; Crespi CL; Gonzalez FJ; Gelboin HV
Mol Carcinog; 1994 Jul; 10(3):159-68. PubMed ID: 8043197
[TBL] [Abstract][Full Text] [Related]
2. Contribution of human cytochrome P450 to benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol metabolism, as predicted from heterologous expression in yeast.
Gautier JC; Lecoeur S; Cosme J; Perret A; Urban P; Beaune P; Pompon D
Pharmacogenetics; 1996 Dec; 6(6):489-99. PubMed ID: 9014198
[TBL] [Abstract][Full Text] [Related]
3. Metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-diol by human cytochrome P450 1B1.
Kim JH; Stansbury KH; Walker NJ; Trush MA; Strickland PT; Sutter TR
Carcinogenesis; 1998 Oct; 19(10):1847-53. PubMed ID: 9806168
[TBL] [Abstract][Full Text] [Related]
4. Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.
Shimada T; Gillam EM; Oda Y; Tsumura F; Sutter TR; Guengerich FP; Inoue K
Chem Res Toxicol; 1999 Jul; 12(7):623-9. PubMed ID: 10409402
[TBL] [Abstract][Full Text] [Related]
5. Specificity of cDNA-expressed human and rodent cytochrome P450s in the oxidative metabolism of the potent carcinogen 7,12-dimethylbenz[a]anthracene.
Shou M; Korzekwa KR; Krausz KW; Buters JT; Grogan J; Goldfarb I; Hardwick JP; Gonzalez FJ; Gelboin HV
Mol Carcinog; 1996 Dec; 17(4):241-9. PubMed ID: 8989918
[TBL] [Abstract][Full Text] [Related]
6. Stereoselective epoxidation and hydration at the K-region of polycyclic aromatic hydrocarbons by cDNA-expressed cytochromes P450 1A1, 1A2, and epoxide hydrolase.
Shou M; Gonzalez FJ; Gelboin HV
Biochemistry; 1996 Dec; 35(49):15807-13. PubMed ID: 8961944
[TBL] [Abstract][Full Text] [Related]
7. Metabolic activation of polycyclic aromatic hydrocarbons and other procarcinogens by cytochromes P450 1A1 and P450 1B1 allelic variants and other human cytochromes P450 in Salmonella typhimurium NM2009.
Shimada T; Oda Y; Gillam EM; Guengerich FP; Inoue K
Drug Metab Dispos; 2001 Sep; 29(9):1176-82. PubMed ID: 11502724
[TBL] [Abstract][Full Text] [Related]
8. Metabolic activation of the potent carcinogen dibenzo[a,h]anthracene by cDNA-expressed human cytochromes P450.
Shou M; Krausz KW; Gonzalez FJ; Gelboin HV
Arch Biochem Biophys; 1996 Apr; 328(1):201-7. PubMed ID: 8638931
[TBL] [Abstract][Full Text] [Related]
9. Metabolic activation of racemic and enantiomeric trans-8, 9-dihydroxy-8,9-dihydrodibenzo[a,l]pyrene (dibenzo[def,p]chrysene) to dibenzo[a,l]pyrene-bis-dihydrodiols by induced rat liver microsomes and a recombinant human P450 1A1 system: the role of the K-region-derived metabolic intermediates in the formation of dibenzo[a,l]pyrene-DNA adducts.
Nesnow S; Davis C; Padgett W; George M; Lambert G; Meyers F; Allison J; Adams L; King LC
Chem Res Toxicol; 1998 Dec; 11(12):1596-607. PubMed ID: 9860506
[TBL] [Abstract][Full Text] [Related]
10. Comparative metabolism of the aza polynuclear aromatic hydrocarbon dibenz[a,h]acridine by recombinant human and rat cytochrome P450s.
Yuan ZX; Kumar S; Sikka HC
Chem Res Toxicol; 2004 May; 17(5):672-8. PubMed ID: 15144224
[TBL] [Abstract][Full Text] [Related]
11. Metabolic activation of dibenzo[a,l]pyrene by human cytochrome P450 1A1 and P450 1B1 expressed in V79 Chinese hamster cells.
Luch A; Schober W; Soballa VJ; Raab G; Greim H; Jacob J; Doehmer J; Seidel A
Chem Res Toxicol; 1999 Apr; 12(4):353-64. PubMed ID: 10207125
[TBL] [Abstract][Full Text] [Related]
12. Roles of individual human cytochrome P-450 enzymes in the bioactivation of benzo(a)pyrene, 7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene, and other dihydrodiol derivatives of polycyclic aromatic hydrocarbons.
Shimada T; Martin MV; Pruess-Schwartz D; Marnett LJ; Guengerich FP
Cancer Res; 1989 Nov; 49(22):6304-12. PubMed ID: 2509067
[TBL] [Abstract][Full Text] [Related]
13. Metabolism of 5-methylchrysene and 6-methylchrysene by human hepatic and pulmonary cytochrome P450 enzymes.
Koehl W; Amin S; Staretz ME; Ueng YF; Yamazaki H; Tateishi T; Guengerich FP; Hecht SS
Cancer Res; 1996 Jan; 56(2):316-24. PubMed ID: 8542586
[TBL] [Abstract][Full Text] [Related]
14. Inhibition of human cytochrome P450 1A1-, 1A2-, and 1B1-mediated activation of procarcinogens to genotoxic metabolites by polycyclic aromatic hydrocarbons.
Shimada T; Guengerich FP
Chem Res Toxicol; 2006 Feb; 19(2):288-94. PubMed ID: 16485905
[TBL] [Abstract][Full Text] [Related]
15. In vitro metabolism of benzo[a]pyrene-7,8-dihydrodiol and dibenzo[def,p]chrysene-11,12 diol in rodent and human hepatic microsomes.
Smith JN; Mehinagic D; Nag S; Crowell SR; Corley RA
Toxicol Lett; 2017 Mar; 269():23-32. PubMed ID: 28119020
[TBL] [Abstract][Full Text] [Related]
16. The K-region trans-8,9-diol does not significantly contribute as an intermediate in the metabolic activation of dibenzo[a,l]pyrene to DNA-binding metabolites by human cytochrome P450 1A1 or 1B1.
Luch A; Kishiyama S; Seidel A; Doehmer J; Greim H; Baird WM
Cancer Res; 1999 Sep; 59(18):4603-9. PubMed ID: 10493514
[TBL] [Abstract][Full Text] [Related]
17. Oxidation of benzo[a]pyrene by recombinant human cytochrome P450 enzymes.
Bauer E; Guo Z; Ueng YF; Bell LC; Zeldin D; Guengerich FP
Chem Res Toxicol; 1995; 8(1):136-42. PubMed ID: 7703357
[TBL] [Abstract][Full Text] [Related]
18. Differential metabolism of benzo[a]pyrene and benzo[a]pyrene-7,8-dihydrodiol by human CYP1A1 variants.
Schwarz D; Kisselev P; Cascorbi I; Schunck WH; Roots I
Carcinogenesis; 2001 Mar; 22(3):453-9. PubMed ID: 11238186
[TBL] [Abstract][Full Text] [Related]
19. A quantitative comparison of dibenzo[a,l]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes.
King LC; Adams L; Allison J; Kohan MJ; Nelson G; Desai D; Amin S; Ross JA
Mol Carcinog; 1999 Oct; 26(2):74-82. PubMed ID: 10506751
[TBL] [Abstract][Full Text] [Related]
20. Competing roles of cytochrome P450 1A1/1B1 and aldo-keto reductase 1A1 in the metabolic activation of (+/-)-7,8-dihydroxy-7,8-dihydro-benzo[a]pyrene in human bronchoalveolar cell extracts.
Jiang H; Shen YM; Quinn AM; Penning TM
Chem Res Toxicol; 2005 Feb; 18(2):365-74. PubMed ID: 15720144
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
