These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
116 related articles for article (PubMed ID: 8043612)
21. Design of dihydrofolate reductase inhibitors from X-ray crystal structures. Roth B Fed Proc; 1986 Nov; 45(12):2765-72. PubMed ID: 3533642 [TBL] [Abstract][Full Text] [Related]
22. Methotrexate resistance of mouse dihydrofolate reductase: effect of substitution of phenylalanine-31 by serine or tryptophan. Evenson DA; Adams J; McIvor RS; Wagner CR J Med Chem; 1996 Apr; 39(9):1763-6. PubMed ID: 8627598 [TBL] [Abstract][Full Text] [Related]
23. Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression. Mayer-Kuckuk P; Banerjee D; Malhotra S; Doubrovin M; Iwamoto M; Akhurst T; Balatoni J; Bornmann W; Finn R; Larson S; Fong Y; Gelovani Tjuvajev J; Blasberg R; Bertino JR Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3400-5. PubMed ID: 11891321 [TBL] [Abstract][Full Text] [Related]
24. Protection of CCRF-CEM human lymphoid cells from antifolates by retroviral gene transfer of variants of murine dihydrofolate reductase. Mareya SM; Sorrentino BP; Blakley RL Cancer Gene Ther; 1998; 5(4):225-35. PubMed ID: 9694074 [TBL] [Abstract][Full Text] [Related]
25. Structural comparison of chromosomal and exogenous dihydrofolate reductase from Staphylococcus aureus in complex with the potent inhibitor trimethoprim. Heaslet H; Harris M; Fahnoe K; Sarver R; Putz H; Chang J; Subramanyam C; Barreiro G; Miller JR Proteins; 2009 Aug; 76(3):706-17. PubMed ID: 19280600 [TBL] [Abstract][Full Text] [Related]
26. Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae. Lee J; Yennawar NH; Gam J; Benkovic SJ Biochemistry; 2010 Jan; 49(1):195-206. PubMed ID: 19950924 [TBL] [Abstract][Full Text] [Related]
27. Identification of highly potent and selective inhibitors of Toxoplasma gondii dihydrofolate reductase. Chio LC; Queener SF Antimicrob Agents Chemother; 1993 Sep; 37(9):1914-23. PubMed ID: 8239605 [TBL] [Abstract][Full Text] [Related]
28. Structural Insights into Mycobacterium tuberculosis Rv2671 Protein as a Dihydrofolate Reductase Functional Analogue Contributing to para-Aminosalicylic Acid Resistance. Cheng YS; Sacchettini JC Biochemistry; 2016 Feb; 55(7):1107-19. PubMed ID: 26848874 [TBL] [Abstract][Full Text] [Related]
29. Super in vitro synergy between inhibitors of dihydrofolate reductase and inhibitors of other folate-requiring enzymes: the critical role of polyglutamylation. Faessel HM; Slocum HK; Jackson RC; Boritzki TJ; Rustum YM; Nair MG; Greco WR Cancer Res; 1998 Jul; 58(14):3036-50. PubMed ID: 9679969 [TBL] [Abstract][Full Text] [Related]
30. Selective inhibitors of Candida albicans dihydrofolate reductase: activity and selectivity of 5-(arylthio)-2,4-diaminoquinazolines. Chan JH; Hong JS; Kuyper LF; Baccanari DP; Joyner SS; Tansik RL; Boytos CM; Rudolph SK J Med Chem; 1995 Sep; 38(18):3608-16. PubMed ID: 7658448 [TBL] [Abstract][Full Text] [Related]
31. Comparison of solution structures of dihydrofolate reductases and enzyme-ligand complexes using cross-reacting antibodies. Ratnam M; Delcamp TJ; Freisheim JH Biochemistry; 1986 Sep; 25(19):5453-9. PubMed ID: 2430612 [TBL] [Abstract][Full Text] [Related]
32. Calorimetric studies of ligand binding in R67 dihydrofolate reductase. Jackson M; Chopra S; Smiley RD; Maynord PO; Rosowsky A; London RE; Levy L; Kalman TI; Howell EE Biochemistry; 2005 Sep; 44(37):12420-33. PubMed ID: 16156655 [TBL] [Abstract][Full Text] [Related]
33. Inhibition of Pneumocystis dihydrofolate reductase by analogs of pyrimethamine, methotrexate and trimetrexate. Queener SF J Protozool; 1991; 38(6):154S-157S. PubMed ID: 1840146 [TBL] [Abstract][Full Text] [Related]
34. Characterization and comparative studies of zebrafish and human recombinant dihydrofolate reductases--inhibition by folic acid and polyphenols. Kao TT; Wang KC; Chang WN; Lin CY; Chen BH; Wu HL; Shi GY; Tsai JN; Fu TF Drug Metab Dispos; 2008 Mar; 36(3):508-16. PubMed ID: 18056255 [TBL] [Abstract][Full Text] [Related]
35. Dihydrofolate reductase as a therapeutic target. Schweitzer BI; Dicker AP; Bertino JR FASEB J; 1990 May; 4(8):2441-52. PubMed ID: 2185970 [TBL] [Abstract][Full Text] [Related]
36. Methotrexate resistance in an in vivo mouse tumor due to a non-active-site dihydrofolate reductase mutation. Dicker AP; Waltham MC; Volkenandt M; Schweitzer BI; Otter GM; Schmid FA; Sirotnak FM; Bertino JR Proc Natl Acad Sci U S A; 1993 Dec; 90(24):11797-801. PubMed ID: 8265628 [TBL] [Abstract][Full Text] [Related]
37. Impairments in antifolate transport are common in retinoblastoma tumor samples. Gorlick RG; Abramson DH; Sowers R; Mazza BA; Dunkel IJ Pediatr Blood Cancer; 2008 Mar; 50(3):573-6. PubMed ID: 17554792 [TBL] [Abstract][Full Text] [Related]
38. Differential alterations of dihydrofolate reductase gene in human leukemia cell lines made resistant to various folate analogues. Miyachi H; Takemura Y; Kobayashi H; Ando K; Ando Y Jpn J Cancer Res; 1993 Jan; 84(1):9-12. PubMed ID: 8449831 [TBL] [Abstract][Full Text] [Related]
39. Circular dichroism studies of dihydrofolate reductase from a methotrexate-resistant strain of Escherichia coli B, MB 1428: ternary complexes. Greenfield NJ Biochim Biophys Acta; 1975 Sep; 403(1):32-46. PubMed ID: 240430 [TBL] [Abstract][Full Text] [Related]
40. Two distinct types of trimethoprim-resistant dihydrofolate reductase specified by R-plasmids of different compatibility groups. Pattishall KH; Acar J; Burchall JJ; Goldstein FW; Harvey RJ J Biol Chem; 1977 Apr; 252(7):2319-23. PubMed ID: 14961 [TBL] [Abstract][Full Text] [Related] [Previous] [Next] [New Search]