BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

80 related articles for article (PubMed ID: 8053939)

  • 1. Inhibition of human sputum elastase by 7-substituted 5-methyl-2-isopropylamino-4H-3,1-benzoxazin-4-ones.
    Uejima Y; Oshida J; Kawabata H; Kokubo M; Kato Y; Fujii K
    Biochem Pharmacol; 1994 Jul; 48(2):426-8. PubMed ID: 8053939
    [TBL] [Abstract][Full Text] [Related]  

  • 2. 5-Methyl-4H-3,1-benzoxazin-4-one derivatives: specific inhibitors of human leukocyte elastase.
    Uejima Y; Kokubo M; Oshida J; Kawabata H; Kato Y; Fujii K
    J Pharmacol Exp Ther; 1993 May; 265(2):516-23. PubMed ID: 8496803
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of chymotrypsin and pancreatic elastase by 4H-3,1-benzoxazin-4-ones.
    Neumann U; Stürzebecher J; Leistner S; Vieweg H
    J Enzyme Inhib; 1991; 4(3):227-32. PubMed ID: 2037867
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design and synthesis of 4H-3,1-benzoxazin-4-ones as potent alternate substrate inhibitors of human leukocyte elastase.
    Krantz A; Spencer RW; Tam TF; Liak TJ; Copp LJ; Thomas EM; Rafferty SP
    J Med Chem; 1990 Feb; 33(2):464-79. PubMed ID: 2299617
    [TBL] [Abstract][Full Text] [Related]  

  • 5. A new class of heterocyclic serine protease inhibitors. Inhibition of human leukocyte elastase, porcine pancreatic elastase, cathepsin G, and bovine chymotrypsin A alpha with substituted benzoxazinones, quinazolines, and anthranilates.
    Teshima T; Griffin JC; Powers JC
    J Biol Chem; 1982 May; 257(9):5085-91. PubMed ID: 7040392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of serine proteases by benzoxazinones: effects of electron withdrawal and 5-substitution.
    Spencer RW; Copp LJ; Bonaventura B; Tam TF; Liak TJ; Billedeau RJ; Krantz A
    Biochem Biophys Res Commun; 1986 Nov; 140(3):928-33. PubMed ID: 3535800
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of human sputum elastase by substituted 2-pyrones.
    Cook L; Ternai B; Ghosh P
    J Med Chem; 1987 Jun; 30(6):1017-23. PubMed ID: 3647139
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of leukocytic elastase from purulent sputum by alpha 1 -antitrypsin.
    Lieberman J; Kaneshiro W
    J Lab Clin Med; 1972 Jul; 80(1):88-101. PubMed ID: 5033900
    [No Abstract]   [Full Text] [Related]  

  • 9. Studies on 2-benzyloxy-4H-3,1-benzoxazin-4-ones as serine protease inhibitors.
    Gütschow M; Neumann U; Sieler J; Eger K
    Pharm Acta Helv; 1998 Jul; 73(2):95-103. PubMed ID: 9700938
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis and in vitro and in vivo evaluation of the 2-(6'methoxy-3',4'-dihydro-1'-naphtyl)-4H-3,1-benzoxazin-4- one as a new potent substrate inhibitor of human leukocyte elastase.
    Arcadi A; Asti C; Brandolini L; Caselli G; Marinelli F; Ruggieri V
    Bioorg Med Chem Lett; 1999 May; 9(9):1291-4. PubMed ID: 10340616
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suicide inactivation of chymotrypsin by benzoxazinones.
    Hedstrom L; Moorman AR; Dobbs J; Abeles RH
    Biochemistry; 1984 Apr; 23(8):1753-9. PubMed ID: 6562904
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Clarification of mechanism of human sputum elastase inhibition by a new inhibitor, ONO-5046, using electrospray ionization mass spectrometry.
    Nakayama Y; Odagaki Y; Fujita S; Matsuoka S; Hamanaka N; Nakai H; Toda M
    Bioorg Med Chem Lett; 2002 Sep; 12(17):2349-53. PubMed ID: 12161131
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Structure-activity studies on 2-aryl-4H-3,1-benzoxazin-4-ones.
    Hadfield JA; Pavlidis VH; McGown AT; Whitworth C; Perry PJ; Fox BW
    Anticancer Drugs; 1994 Oct; 5(5):533-8. PubMed ID: 7858285
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mechanism for slow-binding inhibition of human leukocyte elastase by valine-derived benzoxazinones.
    Stein RL; Strimpler AM; Viscarello BR; Wildonger RA; Mauger RC; Trainor DA
    Biochemistry; 1987 Jun; 26(13):4126-30. PubMed ID: 3651441
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Pharmacological profile of the substituted beta-lactam L-659,286: a member of a new class of human PMN elastase inhibitors.
    Bonney RJ; Ashe B; Maycock A; Dellea P; Hand K; Osinga D; Fletcher D; Mumford R; Davies P; Frankenfield D
    J Cell Biochem; 1989 Jan; 39(1):47-53. PubMed ID: 2497109
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A comparison of alpha 1-proteinase inhibitor methoxysuccinyl-Ala-Ala-Pro-Val-chloromethylketone and specific beta-lactam inhibitors in an acute model of human polymorphonuclear leukocyte elastase-induced lung hemorrhage in the hamster.
    Fletcher DS; Osinga DG; Hand KM; Dellea PS; Ashe BM; Mumford RA; Davies P; Hagmann W; Finke PE; Doherty JB
    Am Rev Respir Dis; 1990 Mar; 141(3):672-7. PubMed ID: 2310097
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Proteases from purulent sputum. Purification and properties of the elastase and chymotrypsin-like enzymes.
    Twumasi DY; Liener IE
    J Biol Chem; 1977 Mar; 252(6):1917-26. PubMed ID: 14955
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibition of human leukocyte elastase, cathepsin G, chymotrypsin A alpha, and porcine pancreatic elastase with substituted isobenzofuranones and benzopyrandiones.
    Hemmi K; Harper JW; Powers JC
    Biochemistry; 1985 Apr; 24(8):1841-8. PubMed ID: 3848330
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Specific inhibition of human leukocyte elastase by substituted alpha-pyrones.
    Groutas WC; Abrams WR; Carroll RT; Moi MK; Miller KE; Margolis MT
    Experientia; 1984 Apr; 40(4):361-2. PubMed ID: 6562017
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Neutrophil-mediated vascular leakage is not suppressed by leukocyte elastase inhibitors.
    Rosengren S; Arfors KE
    Am J Physiol; 1990 Oct; 259(4 Pt 2):H1288-94. PubMed ID: 2221132
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.