BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

219 related articles for article (PubMed ID: 8060993)

  • 1. Stimulation of site-specific topoisomerase II-mediated DNA cleavage by an N-methylpyrrolecarboxamide-anilinoacridine conjugate: relation to DNA binding.
    Fossé P; René B; Saucier JM; Hénichart JP; Waring MJ; Colson P; Houssier C; Bailly C
    Biochemistry; 1994 Aug; 33(33):9865-74. PubMed ID: 8060993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA cleavage by topoisomerase I in the presence of indolocarbazole derivatives of rebeccamycin.
    Bailly C; Riou JF; Colson P; Houssier C; Rodrigues-Pereira E; Prudhomme M
    Biochemistry; 1997 Apr; 36(13):3917-29. PubMed ID: 9092822
    [TBL] [Abstract][Full Text] [Related]  

  • 3. From amsacrine to DACA (N-[2-(dimethylamino)ethyl]acridine-4-carboxamide): selectivity for topoisomerases I and II among acridine derivatives.
    Finlay GJ; Riou JF; Baguley BC
    Eur J Cancer; 1996 Apr; 32A(4):708-14. PubMed ID: 8695277
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The 1'-substituent on the anilino ring of the antitumor drug amsacrine is a critical element for topoisomerase II inhibition and cytotoxicity.
    Rene B; Fosse P; Khelifa T; Jacquemin-Sablon A; Bailly C
    Mol Pharmacol; 1996 Feb; 49(2):343-50. PubMed ID: 8632768
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Stimulation by gamma-carboline derivatives (simplified analogues of antitumor ellipticines) of site specific DNA cleavage by calf DNA topoisomerase II.
    Fossé P; René B; Saucier JM; Nguyen CH; Bisagni E; Paoletti C
    Biochem Pharmacol; 1990 Feb; 39(4):669-76. PubMed ID: 2154990
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Sequence selectivity of topoisomerase II DNA cleavage stimulated by mitoxantrone derivatives: relationships to drug DNA binding and cellular effects.
    De Isabella P; Capranico G; Palumbo M; Sissi C; Krapcho AP; Zunino F
    Mol Pharmacol; 1993 May; 43(5):715-21. PubMed ID: 8388987
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Novel trifluoromethylated 9-amino-3,4-dihydroacridin-1(2H)-ones act as covalent poisons of human topoisomerase IIα.
    Infante Lara L; Sledge A; Laradji A; Okoro CO; Osheroff N
    Bioorg Med Chem Lett; 2017 Feb; 27(3):586-589. PubMed ID: 27998679
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Substitution at the F-ring N-imide of the indolocarbazole antitumor drug NB-506 increases the cytotoxicity, DNA binding, and topoisomerase I inhibition activities.
    Bailly C; Qu X; Chaires JB; Colson P; Houssier C; Ohkubo M; Nishimura S; Yoshinari T
    J Med Chem; 1999 Jul; 42(15):2927-35. PubMed ID: 10425102
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Linkage of a triple helix-forming oligonucleotide to amsacrine-4-carboxamide derivatives modulates the sequence-selectivity of topoisomerase II-mediated DNA cleavage.
    Arimondo P; Bailly C; Boutorine A; Asseline U; Sun JS; Garestier T; Hélène C
    Nucleosides Nucleotides Nucleic Acids; 2000 Aug; 19(8):1205-18. PubMed ID: 11097051
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Topoisomerase II mediated DNA lesions induced by acridine-4-carboxamide and 2-(4-pyridyl)quinoline-8-carboxamide.
    Woynarowski JM; McCarthy K; Reynolds B; Beerman TA; Denny WA
    Anticancer Drug Des; 1994 Feb; 9(1):9-24. PubMed ID: 8141968
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Base sequence determinants of amonafide stimulation of topoisomerase II DNA cleavage.
    De Isabella P; Zunino F; Capranico G
    Nucleic Acids Res; 1995 Jan; 23(2):223-9. PubMed ID: 7862525
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Similar sequence specificity of mitoxantrone and VM-26 stimulation of in vitro DNA cleavage by mammalian DNA topoisomerase II.
    Capranico G; De Isabella P; Tinelli S; Bigioni M; Zunino F
    Biochemistry; 1993 Mar; 32(12):3038-46. PubMed ID: 8384486
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA damage by antitumor acridines mediated by mammalian DNA topoisomerase II.
    Rowe TC; Chen GL; Hsiang YH; Liu LF
    Cancer Res; 1986 Apr; 46(4 Pt 2):2021-6. PubMed ID: 3004716
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Covalent attachment of ethidium to DNA results in enhanced topoisomerase II-mediated DNA cleavage.
    Marx G; Zhou H; Graves DE; Osheroff N
    Biochemistry; 1997 Dec; 36(50):15884-91. PubMed ID: 9398321
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Analysis of eukaryotic topoisomerase II cleavage sites in the presence of the quinolone CP-115,953 reveals drug-dependent and -independent recognition elements.
    Spitzner JR; Chung IK; Gootz TD; McGuirk PR; Muller MT
    Mol Pharmacol; 1995 Aug; 48(2):238-49. PubMed ID: 7651357
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Relative activity of structural analogues of amsacrine against human leukemia cell lines containing amsacrine-sensitive or -resistant forms of topoisomerase II: use of computer simulations in new drug development.
    Zwelling LA; Mitchell MJ; Satitpunwaycha P; Mayes J; Altschuler E; Hinds M; Baguley BC
    Cancer Res; 1992 Jan; 52(1):209-17. PubMed ID: 1309224
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Design of two etoposide-amsacrine conjugates: topoisomerase II and tubuline polymerization inhibition and relation to cytotoxicity.
    Arimondo P; Boukarim C; Bailly C; Dauzonne D; Monneret C
    Anticancer Drug Des; 2000 Dec; 15(6):413-21. PubMed ID: 11716434
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mode of action of topoisomerase II-targeting agents at a specific DNA sequence. Uncoupling the DNA binding, cleavage and religation events.
    Sørensen BS; Sinding J; Andersen AH; Alsner J; Jensen PB; Westergaard O
    J Mol Biol; 1992 Dec; 228(3):778-86. PubMed ID: 1335085
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Stimulation of topoisomerase II-mediated DNA cleavage by three DNA-intercalating plant alkaloids: cryptolepine, matadine, and serpentine.
    Dassonneville L; Bonjean K; De Pauw-Gillet MC; Colson P; Houssier C; Quetin-Leclercq J; Angenot L; Bailly C
    Biochemistry; 1999 Jun; 38(24):7719-26. PubMed ID: 10387011
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Position-specific effects of base mismatch on mammalian topoisomerase II DNA cleaving activity.
    Bigioni M; Zunino F; Tinelli S; Austin CA; Willmore E; Capranico G
    Biochemistry; 1996 Jan; 35(1):153-9. PubMed ID: 8555169
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.