These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 8062821)

  • 1. Electrostatic attraction by surface charge does not contribute to the catalytic efficiency of acetylcholinesterase.
    Shafferman A; Ordentlich A; Barak D; Kronman C; Ber R; Bino T; Ariel N; Osman R; Velan B
    EMBO J; 1994 Aug; 13(15):3448-55. PubMed ID: 8062821
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Electrostatic influence on the kinetics of ligand binding to acetylcholinesterase. Distinctions between active center ligands and fasciculin.
    Radić Z; Kirchhoff PD; Quinn DM; McCammon JA; Taylor P
    J Biol Chem; 1997 Sep; 272(37):23265-77. PubMed ID: 9287336
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Simulation of charge-mutant acetylcholinesterases.
    Antosiewicz J; McCammon JA; Wlodek ST; Gilson MK
    Biochemistry; 1995 Apr; 34(13):4211-9. PubMed ID: 7703233
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Acetylcholinesterase: role of the enzyme's charge distribution in steering charged ligands toward the active site.
    Antosiewicz J; Wlodek ST; McCammon JA
    Biopolymers; 1996 Jul; 39(1):85-94. PubMed ID: 8924629
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Effective charge on acetylcholinesterase active sites determined from the ionic strength dependence of association rate constants with cationic ligands.
    Nolte HJ; Rosenberry TL; Neumann E
    Biochemistry; 1980 Aug; 19(16):3705-11. PubMed ID: 7407068
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center.
    Shafferman A; Velan B; Ordentlich A; Kronman C; Grosfeld H; Leitner M; Flashner Y; Cohen S; Barak D; Ariel N
    EMBO J; 1992 Oct; 11(10):3561-8. PubMed ID: 1396557
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Theoretical and experimental investigations of electrostatic effects on acetylcholinesterase catalysis and inhibition.
    Malany S; Baker N; Verweyst M; Medhekar R; Quinn DM; Velan B; Kronman C; Shafferman A
    Chem Biol Interact; 1999 May; 119-120():99-110. PubMed ID: 10421443
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket.
    Ordentlich A; Barak D; Kronman C; Flashner Y; Leitner M; Segall Y; Ariel N; Cohen S; Velan B; Shafferman A
    J Biol Chem; 1993 Aug; 268(23):17083-95. PubMed ID: 8349597
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Functional requirements for the optimal catalytic configuration of the AChE active center.
    Shafferman A; Barak D; Kaplan D; Ordentlich A; Kronman C; Velan B
    Chem Biol Interact; 2005 Dec; 157-158():123-31. PubMed ID: 16256968
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Amino acid residues involved in the interaction of acetylcholinesterase and butyrylcholinesterase with the carbamates Ro 02-0683 and bambuterol, and with terbutaline.
    Kovarik Z; Radić Z; Grgas B; Skrinjarić-Spoljar M; Reiner E; Simeon-Rudolf V
    Biochim Biophys Acta; 1999 Aug; 1433(1-2):261-71. PubMed ID: 10446376
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Does "butyrylization" of acetylcholinesterase through substitution of the six divergent aromatic amino acids in the active center gorge generate an enzyme mimic of butyrylcholinesterase?
    Kaplan D; Ordentlich A; Barak D; Ariel N; Kronman C; Velan B; Shafferman A
    Biochemistry; 2001 Jun; 40(25):7433-45. PubMed ID: 11412096
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Rapid binding of a cationic active site inhibitor to wild type and mutant mouse acetylcholinesterase: Brownian dynamics simulation including diffusion in the active site gorge.
    Tara S; Elcock AH; Kirchhoff PD; Briggs JM; Radic Z; Taylor P; McCammon JA
    Biopolymers; 1998 Dec; 46(7):465-74. PubMed ID: 9838872
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Acetylcholinesterase: diffusional encounter rate constants for dumbbell models of ligand.
    Antosiewicz J; Gilson MK; Lee IH; McCammon JA
    Biophys J; 1995 Jan; 68(1):62-8. PubMed ID: 7711269
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Asp7O in the peripheral anionic site of human butyrylcholinesterase.
    Masson P; Froment MT; Bartels CF; Lockridge O
    Eur J Biochem; 1996 Jan; 235(1-2):36-48. PubMed ID: 8631355
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Unmasking tandem site interaction in human acetylcholinesterase. Substrate activation with a cationic acetanilide substrate.
    Johnson JL; Cusack B; Davies MP; Fauq A; Rosenberry TL
    Biochemistry; 2003 May; 42(18):5438-52. PubMed ID: 12731886
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Aromatic amino-acid residues at the active and peripheral anionic sites control the binding of E2020 (Aricept) to cholinesterases.
    Saxena A; Fedorko JM; Vinayaka CR; Medhekar R; Radić Z; Taylor P; Lockridge O; Doctor BP
    Eur J Biochem; 2003 Nov; 270(22):4447-58. PubMed ID: 14622273
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Allosteric control of acetylcholinesterase catalysis by fasciculin.
    Radić Z; Quinn DM; Vellom DC; Camp S; Taylor P
    J Biol Chem; 1995 Sep; 270(35):20391-9. PubMed ID: 7657613
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Acetylcholinesterase active centre and gorge conformations analysed by combinatorial mutations and enantiomeric phosphonates.
    Kovarik Z; Radić Z; Berman HA; Simeon-Rudolf V; Reiner E; Taylor P
    Biochem J; 2003 Jul; 373(Pt 1):33-40. PubMed ID: 12665427
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Acetylcholinesterase: electrostatic steering increases the rate of ligand binding.
    Tan RC; Truong TN; McCammon JA; Sussman JL
    Biochemistry; 1993 Jan; 32(2):401-3. PubMed ID: 8422348
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Interfacial biocatalysis on charged and immobilized substrates: the roles of enzyme and substrate surface charge.
    Feller BE; Kellis JT; Cascão-Pereira LG; Robertson CR; Frank CW
    Langmuir; 2011 Jan; 27(1):250-63. PubMed ID: 21128607
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.