121 related articles for article (PubMed ID: 8064803)
1. Structure-affinity relationship studies on 5-HT1A receptor ligands. 2. Heterobicyclic phenylpiperazines with N4-aralkyl substituents.
van Steen BJ; van Wijngaarden I; Tulp MT; Soudijn W
J Med Chem; 1994 Aug; 37(17):2761-73. PubMed ID: 8064803
[TBL] [Abstract][Full Text] [Related]
2. Structure-affinity relationship studies on 5-HT1A receptor ligands. 1. Heterobicyclic phenylpiperazines with N4-alkyl substituents.
van Steen BJ; van Wijngaarden I; Tulp MT; Soudijn W
J Med Chem; 1993 Sep; 36(19):2751-60. PubMed ID: 8410989
[TBL] [Abstract][Full Text] [Related]
3. N4-unsubstituted N1-arylpiperazines as high-affinity 5-HT1A receptor ligands.
Kuipers W; van Wijngaarden I; Kruse CG; ter Horst-van Amstel M; Tulp MT; IJzerman AP
J Med Chem; 1995 May; 38(11):1942-54. PubMed ID: 7783126
[TBL] [Abstract][Full Text] [Related]
4. 5-HT1A-versus D2-receptor selectivity of flesinoxan and analogous N4-substituted N1-arylpiperazines.
Kuipers W; Kruse CG; van Wijngaarden I; Standaar PJ; Tulp MT; Veldman N; Spek AL; IJzerman AP
J Med Chem; 1997 Jan; 40(3):300-12. PubMed ID: 9022796
[TBL] [Abstract][Full Text] [Related]
5. Functional characteristics of a series of N4-substituted 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazines as 5-HT1A receptor ligands. Structure-activity relationships.
van Steen BJ; van Wijngaarden I; Ronken E; Soudijn W
Bioorg Med Chem Lett; 1998 Sep; 8(18):2457-62. PubMed ID: 9873561
[TBL] [Abstract][Full Text] [Related]
6. A series of N4-imidoethyl derivatives of 1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine as 5-HT1A receptor ligands: synthesis and structure-affinity relationships.
van Steen BJ; van Wijngaarden I; Tulp MT; Soudijn W
J Med Chem; 1995 Oct; 38(21):4303-8. PubMed ID: 7473558
[TBL] [Abstract][Full Text] [Related]
7. Synthesis and structure-activity relationships of a new model of arylpiperazines. 2. Three-dimensional quantitative structure-activity relationships of hydantoin-phenylpiperazine derivatives with affinity for 5-HT1A and alpha 1 receptors. A comparison of CoMFA models.
López-Rodríguez ML; Rosado ML; Benhamú B; Morcillo MJ; Fernández E; Schaper KJ
J Med Chem; 1997 May; 40(11):1648-56. PubMed ID: 9171874
[TBL] [Abstract][Full Text] [Related]
8. Synthesis and structure-activity relationships of a new model of arylpiperazines. 4. 1-[omega-(4-Arylpiperazin-1-yl)alkyl]-3-(diphenylmethylene) - 2, 5-pyrrolidinediones and -3-(9H-fluoren-9-ylidene)-2, 5-pyrrolidinediones: study of the steric requirements of the terminal amide fragment on 5-HT1A affinity/selectivity.
López-Rodríguez ML; Morcillo MJ; Rovat TK; Fernández E; Vicente B; Sanz AM; Hernández M; Orensanz L
J Med Chem; 1999 Jan; 42(1):36-49. PubMed ID: 9888831
[TBL] [Abstract][Full Text] [Related]
9. [[(Arylpiperazinyl)alkyl]thio]thieno[2,3-d]pyrimidinone derivatives as high-affinity, selective 5-HT1A receptor ligands.
Modica M; Santagati M; Russo F; Parotti L; De Gioia L; Selvaggini C; Salmona M; Mennini T
J Med Chem; 1997 Feb; 40(4):574-85. PubMed ID: 9046348
[TBL] [Abstract][Full Text] [Related]
10. Synthesis and structure-activity relationships of a new model of arylpiperazines. Study of the 5-HT(1a)/alpha(1)-adrenergic receptor affinity by classical hansch analysis, artificial neural networks, and computational simulation of ligand recognition.
López-Rodríguez ML; Morcillo MJ; Fernández E; Rosado ML; Pardo L; Schaper K
J Med Chem; 2001 Jan; 44(2):198-207. PubMed ID: 11170629
[TBL] [Abstract][Full Text] [Related]
11. Structure-activity relationship studies of CNS agents. Part VIII. Bulk tolerance around the protonation center of 4-substituted 1-(3-chlorophenyl)piperazines at 5-HT1A and 5-HT2 receptors.
Mokrosz JL; Charakchieva-Minol S; Paluchowska MH; Cegła MT
Pol J Pharmacol Pharm; 1992; 44(6):595-607. PubMed ID: 1305959
[TBL] [Abstract][Full Text] [Related]
12. New sigma and 5-HT1A receptor ligands: omega-(tetralin-1-yl)-n-alkylamine derivatives.
Berardi F; Colabufo NA; Giudice G; Perrone R; Tortorella V; Govoni S; Lucchi L
J Med Chem; 1996 Jan; 39(1):176-82. PubMed ID: 8568804
[TBL] [Abstract][Full Text] [Related]
13. 1-Substituted-4-[3-(1,2,3,4-tetrahydro-5- or 7-methoxynaphthalen-1-yl)propyl]piperazines: influence of the N-1 piperazine substituent on 5-HT1A receptor affinity and selectivity versus D2 and alpha1 receptors. Part 6.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
Bioorg Med Chem; 2000 May; 8(5):873-81. PubMed ID: 10881999
[TBL] [Abstract][Full Text] [Related]
14. 1-aryl-4-[(5-methoxy-1,2,3, 4-tetrahydronaphthalen-1-yl)alkyl]piperazines and their analogues: influence of the stereochemistry of the tetrahydronaphthalen-1-yl nucleus on 5-HT1A receptor affinity and selectivity versus alpha1 and D2 receptors. 5.
Perrone R; Berardi F; Colabufo NA; Leopoldo M; Tortorella V
J Med Chem; 1999 Feb; 42(3):490-6. PubMed ID: 9986719
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, 5-HT1A and 5-HT2A receptor activity of new 1-phenylpiperazinylpropyl derivatives with arylalkyl substituents in position 7 of purine-2,6-dione.
Chloń G; Pawłowski M; Duszyńska B; Szaro A; Tatarczńska E; Kłodzińska AL; Chojnacka-Wójcik E
Pol J Pharmacol; 2001; 53(4):359-68. PubMed ID: 11990082
[TBL] [Abstract][Full Text] [Related]
16. New benzocycloalkylpiperazines, potent and selective 5-HT1A receptor ligands.
el Ahmad Y; Laurent E; Maillet P; Talab A; Teste JF; Dokhan R; Tran G; Ollivier R
J Med Chem; 1997 Mar; 40(6):952-60. PubMed ID: 9083484
[TBL] [Abstract][Full Text] [Related]
17. Arylpiperazine derivatives as high-affinity 5-HT1A serotonin ligands.
Glennon RA; Naiman NA; Lyon RA; Titeler M
J Med Chem; 1988 Oct; 31(10):1968-71. PubMed ID: 3172131
[TBL] [Abstract][Full Text] [Related]
18. New (2-methoxyphenyl)piperazine derivatives as 5-HT1A receptor ligands with reduced alpha 1-adrenergic activity. Synthesis and structure-affinity relationships.
Orjales A; Alonso-Cires L; Labeaga L; Corcóstegui R
J Med Chem; 1995 Apr; 38(8):1273-7. PubMed ID: 7731013
[TBL] [Abstract][Full Text] [Related]
19. Isoindol-1-one analogues of 4-(2'-methoxyphenyl)-1-[2'-[N-(2"-pyridyl)-p-iodobenzamido]ethyl]pipera zine (p-MPPI) as 5-HT1A receptor ligands.
Zhuang ZP; Kung MP; Mu M; Kung HF
J Med Chem; 1998 Jan; 41(2):157-66. PubMed ID: 9457239
[TBL] [Abstract][Full Text] [Related]
20. Synthesis and structure-activity relationships of a new model of arylpiperazines. 3.1 2-[omega-(4-arylpiperazin-1-yl)alkyl]perhydropyrrolo- [1,2-c]imidazoles and -perhydroimidazo[1,5-a]pyridines: study of the influence of the terminal amide fragment on 5-HT1A affinity/selectivity.
López-Rodríguez ML; Morcillo MJ; Fernández E; Porras E; Murcia M; Sanz AM; Orensanz L
J Med Chem; 1997 Aug; 40(16):2653-6. PubMed ID: 9258372
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
