These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

144 related articles for article (PubMed ID: 8068551)

  • 1. Formation and fate of nephrotoxic and cytotoxic glutathione S-conjugates: cysteine conjugate beta-lyase pathway.
    Dekant W; Vamvakas S; Anders MW
    Adv Pharmacol; 1994; 27():115-62. PubMed ID: 8068551
    [No Abstract]   [Full Text] [Related]  

  • 2. Bioactivation of nephrotoxic haloalkenes by glutathione conjugation: formation of toxic and mutagenic intermediates by cysteine conjugate beta-lyase.
    Dekant W; Vamvakas S; Anders MW
    Drug Metab Rev; 1989; 20(1):43-83. PubMed ID: 2653763
    [No Abstract]   [Full Text] [Related]  

  • 3. Nephrotoxicity of sevoflurane compound A [fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether] in rats: evidence for glutathione and cysteine conjugate formation and the role of renal cysteine conjugate beta-lyase.
    Jin L; Baillie TA; Davis MR; Kharasch ED
    Biochem Biophys Res Commun; 1995 May; 210(2):498-506. PubMed ID: 7755627
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Intranephron distribution of cysteine S-conjugate beta-lyase activity and its implication for hexachloro-1,3-butadiene-induced nephrotoxicity in rats.
    Kim HS; Cha SH; Abraham DG; Cooper AJ; Endou H
    Arch Toxicol; 1997; 71(3):131-41. PubMed ID: 9049049
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells.
    Chen JC; Stevens JL; Trifillis AL; Jones TW
    Toxicol Appl Pharmacol; 1990 May; 103(3):463-73. PubMed ID: 2339419
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Quantitation of multiple pathways for the metabolism of nephrotoxic cysteine conjugates using selective inhibitors of L-alpha-hydroxy acid oxidase (L-amino acid oxidase) and cysteine conjugate beta-lyase.
    Stevens JL; Hatzinger PB; Hayden PJ
    Drug Metab Dispos; 1989; 17(3):297-303. PubMed ID: 2568912
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.
    Lash LH; Sausen PJ; Duescher RJ; Cooley AJ; Elfarra AA
    J Pharmacol Exp Ther; 1994 Apr; 269(1):374-83. PubMed ID: 8169843
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutagenicity of amino acid and glutathione S-conjugates in the Ames test.
    Vamvakas S; Elfarra AA; Dekant W; Henschler D; Anders MW
    Mutat Res; 1988 Sep; 206(1):83-90. PubMed ID: 2901035
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Cysteine conjugate beta-lyase-dependent biotransformation of the cysteine S-conjugates of the sevoflurane degradation product compound A in human, nonhuman primate, and rat kidney cytosol and mitochondria.
    Iyer RA; Anders MW
    Anesthesiology; 1996 Dec; 85(6):1454-61. PubMed ID: 8968194
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mechanism of S-(1,2-dichlorovinyl)glutathione-induced nephrotoxicity.
    Elfarra AA; Jakobson I; Anders MW
    Biochem Pharmacol; 1986 Jan; 35(2):283-8. PubMed ID: 2867768
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Role of cysteine S-conjugate beta-lyase in the metabolism of cisplatin.
    Zhang L; Hanigan MH
    J Pharmacol Exp Ther; 2003 Sep; 306(3):988-94. PubMed ID: 12750429
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Metabolism of compound A by renal cysteine-S-conjugate beta-lyase is not the mechanism of compound A-induced renal injury in the rat.
    Martin JL; Laster MJ; Kandel L; Kerschmann RL; Reed GF; Eger EI
    Anesth Analg; 1996 Apr; 82(4):770-4. PubMed ID: 8615496
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cysteine conjugate beta-lyase-dependent biotransformation of the cysteine S-conjugates of the sevoflurane degradation product 2-(fluoromethoxy)-1,1,3,3,3-pentafluoro-1-propene (compound A).
    Iyer RA; Anders MW
    Chem Res Toxicol; 1997 Jul; 10(7):811-9. PubMed ID: 9250416
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Role of renal cysteine conjugate beta-lyase in the mechanism of compound A nephrotoxicity in rats.
    Kharasch ED; Thorning D; Garton K; Hankins DC; Kilty CG
    Anesthesiology; 1997 Jan; 86(1):160-71. PubMed ID: 9009951
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Organ-specific carcinogenicity of haloalkenes mediated by glutathione conjugation.
    Dekant W; Henschler D
    J Cancer Res Clin Oncol; 1999; 125(3-4):174-81. PubMed ID: 10235471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cysteine conjugate beta-lyase activities in rat kidney cortex: subcellular localization and relationship to the hepatic enzyme.
    Stevens JL
    Biochem Biophys Res Commun; 1985 Jun; 129(2):499-504. PubMed ID: 4015643
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Cysteine conjugate toxicity in a human cell line: correlation with C-S lyase activity in human hepatic tissue.
    Buckberry LD; Blagbrough IS; Shaw PN
    Hum Exp Toxicol; 1993 Jul; 12(4):329-35. PubMed ID: 8104012
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bacterial cysteine conjugate beta-lyase and the metabolism of cysteine S-conjugates: structural requirements for the cleavage of S-conjugates and the formation of reactive intermediates.
    Vamvakas S; Berthold K; Dekant W; Henschler D
    Chem Biol Interact; 1988; 65(1):59-71. PubMed ID: 3278814
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Role of renal metabolism in risk to toxic chemicals.
    Lash LH
    Environ Health Perspect; 1994 Dec; 102 Suppl 11(Suppl 11):75-9. PubMed ID: 7737046
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Glutathione-dependent biosynthesis and bioactivation of S-(1,2-dichlorovinyl)glutathione and S-(1,2-dichlorovinyl)-L-cysteine, the glutathione and cysteine S-conjugates of dichloroacetylene, in rat tissues and subcellular fractions.
    Patel N; Birner G; Dekant W; Anders MW
    Drug Metab Dispos; 1994; 22(1):143-7. PubMed ID: 8149874
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.