BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

475 related articles for article (PubMed ID: 8069858)

  • 1. Effects of human and rat glutathione S-transferases on the covalent DNA binding of the N-acetoxy derivatives of heterocyclic amine carcinogens in vitro: a possible mechanism of organ specificity in their carcinogenesis.
    Lin D; Meyer DJ; Ketterer B; Lang NP; Kadlubar FF
    Cancer Res; 1994 Sep; 54(18):4920-6. PubMed ID: 8069858
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
    Turesky RJ; Lang NP; Butler MA; Teitel CH; Kadlubar FF
    Carcinogenesis; 1991 Oct; 12(10):1839-45. PubMed ID: 1934265
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Metabolic processing and disposition of 2-amino-3-methylimidazo[4,5-f] quinoline (IQ), 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline (MeIQx), and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) in nonhuman primates.
    Snyderwine EG; Turesky RJ; Buonarati MH; Turteltaub KW; Adamson RH
    Princess Takamatsu Symp; 1995; 23():69-77. PubMed ID: 8844797
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enzymatic phase II activation of the N-hydroxylamines of IQ, MeIQx and PhIP by various organs of monkeys and rats.
    Davis CD; Schut HA; Snyderwine EG
    Carcinogenesis; 1993 Oct; 14(10):2091-6. PubMed ID: 8222059
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Protection against 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine cytotoxicity and DNA adduct formation in human prostate by glutathione S-transferase P1.
    Nelson CP; Kidd LC; Sauvageot J; Isaacs WB; De Marzo AM; Groopman JD; Nelson WG; Kensler TW
    Cancer Res; 2001 Jan; 61(1):103-9. PubMed ID: 11196146
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Excretion of food-derived heterocyclic amine carcinogens into breast milk of lactating rats and formation of DNA adducts in the newborn.
    Ghoshal A; Snyderwine EG
    Carcinogenesis; 1993 Nov; 14(11):2199-203. PubMed ID: 8242844
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Metabolism of heterocyclic aromatic amines by human hepatocytes and cytochrome P4501A2.
    Turesky RJ; Guengerich FP; Guillouzo A; Langouët S
    Mutat Res; 2002 Sep; 506-507():187-95. PubMed ID: 12351158
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Glucuronidation of N-hydroxy heterocyclic amines by human and rat liver microsomes.
    Kaderlik KR; Mulder GJ; Turesky RJ; Lang NP; Teitel CH; Chiarelli MP; Kadlubar FF
    Carcinogenesis; 1994 Aug; 15(8):1695-701. PubMed ID: 8055651
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The role of human glutathione S-transferases (hGSTs) in the detoxification of the food-derived carcinogen metabolite N-acetoxy-PhIP, and the effect of a polymorphism in hGSTA1 on colorectal cancer risk.
    Coles B; Nowell SA; MacLeod SL; Sweeney C; Lang NP; Kadlubar FF
    Mutat Res; 2001 Oct; 482(1-2):3-10. PubMed ID: 11535243
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of DNA adducts formed in vitro by reaction of N-hydroxy-2-amino-3-methylimidazo[4,5-f]quinoline and N-hydroxy-2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline at the C-8 and N2 atoms of guanine.
    Turesky RJ; Rossi SC; Welti DH; Lay JO; Kadlubar FF
    Chem Res Toxicol; 1992; 5(4):479-90. PubMed ID: 1391614
    [TBL] [Abstract][Full Text] [Related]  

  • 11. A comprehensive approach to the profiling of the cooked meat carcinogens 2-amino-3,8-dimethylimidazo[4,5-f]quinoxaline, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine, and their metabolites in human urine.
    Gu D; McNaughton L; Lemaster D; Lake BG; Gooderham NJ; Kadlubar FF; Turesky RJ
    Chem Res Toxicol; 2010 Apr; 23(4):788-801. PubMed ID: 20192249
    [TBL] [Abstract][Full Text] [Related]  

  • 12. 32P-postlabeling analysis of IQ, MeIQx and PhIP adducts formed in vitro in DNA and polynucleotides and found in vivo in hepatic DNA from IQ-, MeIQx- and PhIP-treated monkeys.
    Snyderwine EG; Davis CD; Nouso K; Roller PP; Schut HA
    Carcinogenesis; 1993 Jul; 14(7):1389-95. PubMed ID: 8330355
    [TBL] [Abstract][Full Text] [Related]  

  • 13. N-acetyltransferase-dependent activation of 2-hydroxyamino-1-methyl-6-phenylimidazo[4,5-b]pyridine: formation of 2-amino-1-methyl-6-(5-hydroxy)phenylimidazo [4,5-b]pyridine, a possible biomarker for the reactive dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine.
    Frandsen H; Alexander J
    Carcinogenesis; 2000 Jun; 21(6):1197-203. PubMed ID: 10837010
    [TBL] [Abstract][Full Text] [Related]  

  • 14. [Direct detoxification of N-acetoxy-PhIP by tea polyphenols: a possible mechanism for chemoprevention against PhIP-DNA adduct formation in vivo].
    Lin D; Kadlubar FF; Chen J
    Zhonghua Yu Fang Yi Xue Za Zhi; 1998 Sep; 32(5):265-9. PubMed ID: 10322768
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.
    King RS; Teitel CH; Kadlubar FF
    Carcinogenesis; 2000 Jul; 21(7):1347-54. PubMed ID: 10874013
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Phenolics: blocking agents for heterocyclic amine-induced carcinogenesis.
    Hirose M; Takahashi S; Ogawa K; Futakuchi M; Shirai T
    Food Chem Toxicol; 1999; 37(9-10):985-92. PubMed ID: 10541455
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Heterocyclic amine mixture carcinogenesis and its enhancement by caffeine in F344 rats.
    Tsuda H; Sekine K; Uehara N; Takasuka N; Moore MA; Konno Y; Nakashita K; Degawa M
    Cancer Lett; 1999 Sep; 143(2):229-34. PubMed ID: 10503909
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Species differences in the biotransformation of the food-borne carcinogen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by hepatic microsomes and cytosols from humans, rats, and mice.
    Lin DX; Lang NP; Kadlubar FF
    Drug Metab Dispos; 1995 Apr; 23(4):518-24. PubMed ID: 7600922
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Potential chemoprotective effects of the coffee components kahweol and cafestol palmitates via modification of hepatic N-acetyltransferase and glutathione S-transferase activities.
    Huber WW; Teitel CH; Coles BF; King RS; Wiese FW; Kaderlik KR; Casciano DA; Shaddock JG; Mulder GJ; Ilett KF; Kadlubar FF
    Environ Mol Mutagen; 2004; 44(4):265-76. PubMed ID: 15468054
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Effect of dietary constituents with chemopreventive potential on adduct formation of a low dose of the heterocyclic amines PhIP and IQ and phase II hepatic enzymes.
    Dingley KH; Ubick EA; Chiarappa-Zucca ML; Nowell S; Abel S; Ebeler SE; Mitchell AE; Burns SA; Steinberg FM; Clifford AJ
    Nutr Cancer; 2003; 46(2):212-21. PubMed ID: 14690798
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 24.