BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 8071320)

  • 1. Crystallographic structure of human gamma-thrombin.
    Rydel TJ; Yin M; Padmanabhan KP; Blankenship DT; Cardin AD; Correa PE; Fenton JW; Tulinsky A
    J Biol Chem; 1994 Sep; 269(35):22000-6. PubMed ID: 8071320
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
    Vijayalakshmi J; Padmanabhan KP; Mann KG; Tulinsky A
    Protein Sci; 1994 Dec; 3(12):2254-71. PubMed ID: 7756983
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Structure of the hirugen and hirulog 1 complexes of alpha-thrombin.
    Skrzypczak-Jankun E; Carperos VE; Ravichandran KG; Tulinsky A; Westbrook M; Maraganore JM
    J Mol Biol; 1991 Oct; 221(4):1379-93. PubMed ID: 1942057
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Crystal structure of human alpha-thrombin complexed with hirugen and p-amidinophenylpyruvate at 1.6 A resolution.
    Chen Z; Li Y; Mulichak AM; Lewis SD; Shafer JA
    Arch Biochem Biophys; 1995 Sep; 322(1):198-203. PubMed ID: 7574675
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Structures of thrombin complexes with a designed and a natural exosite peptide inhibitor.
    Qiu X; Yin M; Padmanabhan KP; Krstenansky JL; Tulinsky A
    J Biol Chem; 1993 Sep; 268(27):20318-26. PubMed ID: 8376390
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Refined structure of the hirudin-thrombin complex.
    Rydel TJ; Tulinsky A; Bode W; Huber R
    J Mol Biol; 1991 Sep; 221(2):583-601. PubMed ID: 1920434
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Structure of a retro-binding peptide inhibitor complexed with human alpha-thrombin.
    Tabernero L; Chang CY; Ohringer SL; Lau WF; Iwanowicz EJ; Han WC; Wang TC; Seiler SM; Roberts DG; Sack JS
    J Mol Biol; 1995 Feb; 246(1):14-20. PubMed ID: 7853394
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
    Mathews II; Padmanabhan KP; Ganesh V; Tulinsky A; Ishii M; Chen J; Turck CW; Coughlin SR; Fenton JW
    Biochemistry; 1994 Mar; 33(11):3266-79. PubMed ID: 8136362
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Proteolytic formation of either of the two prothrombin activation intermediates results in formation of a hirugen-binding site.
    Liu LW; Ye J; Johnson AE; Esmon CT
    J Biol Chem; 1991 Dec; 266(35):23633-6. PubMed ID: 1748641
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Atomic structures of two nitroxide spin labels complexed with human thrombin: comparison with solution studies.
    Nienaber VL; Berliner LJ
    J Protein Chem; 2000 Feb; 19(2):129-37. PubMed ID: 10945437
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors.
    Qiu X; Padmanabhan KP; Carperos VE; Tulinsky A; Kline T; Maraganore JM; Fenton JW
    Biochemistry; 1992 Dec; 31(47):11689-97. PubMed ID: 1445905
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Structures of thrombin retro-inhibited with SEL2711 and SEL2770 as they relate to factor Xa binding.
    Mochalkin I; Tulinsky A
    Acta Crystallogr D Biol Crystallogr; 1999 Apr; 55(Pt 4):785-93. PubMed ID: 10089309
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.
    Priestle JP; Rahuel J; Rink H; Tones M; Grütter MG
    Protein Sci; 1993 Oct; 2(10):1630-42. PubMed ID: 8251938
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structure of the Ser195Ala mutant of human alpha--thrombin complexed with fibrinopeptide A(7--16): evidence for residual catalytic activity.
    Krishnan R; Sadler JE; Tulinsky A
    Acta Crystallogr D Biol Crystallogr; 2000 Apr; 56(Pt 4):406-10. PubMed ID: 10739913
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The structure of a complex of bovine alpha-thrombin and recombinant hirudin at 2.8-A resolution.
    Vitali J; Martin PD; Malkowski MG; Robertson WD; Lazar JB; Winant RC; Johnson PH; Edwards BF
    J Biol Chem; 1992 Sep; 267(25):17670-8. PubMed ID: 1517214
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neutron and X-ray crystallographic analysis of the human α-thrombin-bivalirudin complex at pD 5.0: protonation states and hydration structure of the enzyme-product complex.
    Yamada T; Kurihara K; Ohnishi Y; Tamada T; Tomoyori K; Masumi K; Tanaka I; Kuroki R; Niimura N
    Biochim Biophys Acta; 2013 Aug; 1834(8):1532-8. PubMed ID: 23712263
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Nuclear magnetic resonance solution structure of hirudin(1-51) and comparison with corresponding three-dimensional structures determined using the complete 65-residue hirudin polypeptide chain.
    Szyperski T; Güntert P; Stone SR; Wüthrich K
    J Mol Biol; 1992 Dec; 228(4):1193-205. PubMed ID: 1335515
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The structure of a complex of recombinant hirudin and human alpha-thrombin.
    Rydel TJ; Ravichandran KG; Tulinsky A; Bode W; Huber R; Roitsch C; Fenton JW
    Science; 1990 Jul; 249(4966):277-80. PubMed ID: 2374926
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The fifth and sixth growth factor-like domains of thrombomodulin bind to the anion-binding exosite of thrombin and alter its specificity.
    Ye J; Liu LW; Esmon CT; Johnson AE
    J Biol Chem; 1992 Jun; 267(16):11023-8. PubMed ID: 1317850
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Structure of thrombin complexed with selective non-electrophilic inhibitors having cyclohexyl moieties at P1.
    Krishnan R; Mochalkin I; Arni R; Tulinsky A
    Acta Crystallogr D Biol Crystallogr; 2000 Mar; 56(Pt 3):294-303. PubMed ID: 10713516
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.