These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

114 related articles for article (PubMed ID: 8073036)

  • 1. A mutational analysis of receptor binding sites of interleukin-1 beta: differences in binding of human interleukin-1 beta muteins to human and mouse receptors.
    Grütter MG; van Oostrum J; Priestle JP; Edelmann E; Joss U; Feige U; Vosbeck K; Schmitz A
    Protein Eng; 1994 May; 7(5):663-71. PubMed ID: 8073036
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Site-directed mutagenesis--molecular biology and rational drug design.
    Ju G; Labriola-Tompkins E; Varnell T; Madison V; Graves B
    Agents Actions Suppl; 1995; 47():155-9. PubMed ID: 7785490
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mapping of receptor binding sites on IL-1 beta by reconstruction of IL-1ra-like domains.
    Boraschi D; Bossù P; Ruggiero P; Tagliabue A; Bertini R; Macchia G; Gasbarro C; Pellegrini L; Melillo G; Ulisse E; Visconti U; Bizzarri C; Del Grosso E; Mackay AR; Frascotti G; Frigerio F; Grifantini R; Grandi G
    J Immunol; 1995 Nov; 155(10):4719-25. PubMed ID: 7594472
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Mapping receptor binding sites in interleukin (IL)-1 receptor antagonist and IL-1 beta by site-directed mutagenesis. Identification of a single site in IL-1ra and two sites in IL-1 beta.
    Evans RJ; Bray J; Childs JD; Vigers GP; Brandhuber BJ; Skalicky JJ; Thompson RC; Eisenberg SP
    J Biol Chem; 1995 May; 270(19):11477-83. PubMed ID: 7744786
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of the discontinuous binding site in human interleukin 1 beta for the type I interleukin 1 receptor.
    Labriola-Tompkins E; Chandran C; Kaffka KL; Biondi D; Graves BJ; Hatada M; Madison VS; Karas J; Kilian PL; Ju G
    Proc Natl Acad Sci U S A; 1991 Dec; 88(24):11182-6. PubMed ID: 1837145
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Loop substitution as a tool to identify active sites of interleukin-1 beta.
    Palla E; Bensi G; Solito E; Buonamassa DT; Fassina G; Raugei G; Spano F; Galeotti C; Mora M; Domenighini M
    J Biol Chem; 1993 Jun; 268(18):13486-92. PubMed ID: 7685764
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Muteins of human interleukin-1 that show enhanced bioactivities.
    Huang JJ; Newton RC; Horuk R; Matthew JB; Covington M; Pezzella K; Lin YA
    FEBS Lett; 1987 Nov; 223(2):294-8. PubMed ID: 2959567
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Crystal structure of the type-I interleukin-1 receptor complexed with interleukin-1beta.
    Vigers GP; Anderson LJ; Caffes P; Brandhuber BJ
    Nature; 1997 Mar; 386(6621):190-4. PubMed ID: 9062193
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A single amino acid difference between human and monkey interleukin (IL)-1beta dictates effective binding to soluble type II IL-1 receptor.
    Smith DE; Ketchem RR; Moore H; Anderson Z; Renshaw BR; Friend DJ; Sims JE
    J Biol Chem; 2002 Dec; 277(49):47619-25. PubMed ID: 12356774
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mapping of neutralizing epitopes and the receptor binding site of human interleukin 1 beta.
    Simon PL; Kumar V; Lillquist JS; Bhatnagar P; Einstein R; Lee J; Porter T; Green D; Sathe G; Young PR
    J Biol Chem; 1993 May; 268(13):9771-9. PubMed ID: 7683661
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Structure-function analysis of human IL-1 alpha: identification of residues required for binding to the human type I IL-1 receptor.
    Labriola-Tompkins E; Chandran C; Varnell TA; Madison VS; Ju G
    Protein Eng; 1993 Jul; 6(5):535-9. PubMed ID: 7692435
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Deletion mutants of human interleukin 1 beta with significantly reduced agonist properties: search for the agonist/antagonist switch in ligands to the interleukin 1 receptors.
    Simoncsits A; Bristulf J; Tjörnhammar ML; Cserzö M; Pongor S; Rybakina E; Gatti S; Bartfai T
    Cytokine; 1994 Mar; 6(2):206-14. PubMed ID: 8032002
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Interleukin-1 beta-specific partial agonists defined by site-directed mutagenesis studies.
    Guinet F; Guitton JD; Gault N; Folliard F; Touchet N; Cherel JM; Crespo A; Destourbe A; Bertrand P; Denefle P
    Eur J Biochem; 1993 Feb; 211(3):583-90. PubMed ID: 8436117
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Identification of interactive sites of proteins and protein receptors by computer-assisted searches for complementary peptide sequences.
    Fassina G; Melli M
    Immunomethods; 1994 Oct; 5(2):114-20. PubMed ID: 7874435
    [TBL] [Abstract][Full Text] [Related]  

  • 15. An antibody to a 17 amino acid synthetic peptide of the type I interleukin-1 receptor preferentially blocks interleukin-1 beta binding.
    Clark BD; Ikejima T; Mancilla J; Orencole SF; Sirko SP; Ishii N; Okuda K; Dinarello CA
    J Interferon Cytokine Res; 1996 Dec; 16(12):1079-88. PubMed ID: 8974012
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A search within the IL-1 type I receptor reveals a peptide with hydropathic complementarity to the IL-1beta trigger loop which binds to IL-1 and inhibits in vitro responses.
    Heal JR; Bino S; Ray KP; Christie G; Miller AD; Raynes JG
    Mol Immunol; 1999 Dec; 36(17):1141-8. PubMed ID: 10698316
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Permuteins of interleukin 1 beta--a simplified approach for the construction of permutated proteins having new termini.
    Horlick RA; George HJ; Cooke GM; Tritch RJ; Newton RC; Dwivedi A; Lischwe M; Salemme FR; Weber PC; Horuk R
    Protein Eng; 1992 Jul; 5(5):427-31. PubMed ID: 1518791
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Model of interaction of the IL-1 receptor accessory protein IL-1RAcP with the IL-1beta/IL-1R(I) complex.
    Casadio R; Frigimelica E; Bossù P; Neumann D; Martin MU; Tagliabue A; Boraschi D
    FEBS Lett; 2001 Jun; 499(1-2):65-8. PubMed ID: 11418113
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Soluble type II interleukin 1 (IL-1) receptor binds and blocks processing of IL-1 beta precursor and loses affinity for IL-1 receptor antagonist.
    Symons JA; Young PR; Duff GW
    Proc Natl Acad Sci U S A; 1995 Feb; 92(5):1714-8. PubMed ID: 7878046
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Refined crystal structure of the interleukin-1 receptor antagonist. Presence of a disulfide link and a cis-proline.
    Schreuder HA; Rondeau JM; Tardif C; Soffientini A; Sarubbi E; Akeson A; Bowlin TL; Yanofsky S; Barrett RW
    Eur J Biochem; 1995 Feb; 227(3):838-47. PubMed ID: 7867645
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 6.