These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

78 related articles for article (PubMed ID: 8073444)

  • 1. Inhibitors of sterol synthesis. Effects of fluorine substitution at carbon atom 25 of cholesterol on its spectral and chromatographic properties and on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Wilson WK; Swaminathan S; Pinkerton FD; Gerst N; Schroepfer GJ
    Steroids; 1994 May; 59(5):310-7. PubMed ID: 8073444
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibitors of sterol synthesis: synthesis and spectral properties of derivatives of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one fluorinated at carbon 7 or carbon 9 and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Siddiqui AU; Swaminathan S; Pinkerton FD; Gerst N; Wilson WK; Choi H; Schroephfer GJ
    Chem Phys Lipids; 1994 Jun; 72(1):59-75. PubMed ID: 7923480
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibitors of sterol synthesis. Chemical synthesis and properties of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluoro-5 alpha-cholest-8(14)-en-15-one and 25,26,26,26,27,27,27-heptafluorocholesterol and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells.
    Swaminathan S; Wilson WK; Pinkerton FD; Gerst N; Ramser M; Schroepfer GJ
    J Lipid Res; 1993 Oct; 34(10):1805-23. PubMed ID: 8245728
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of (25R)-5 alpha-cholest-8(14)-ene-3 beta,15 beta,26-triol, a potential metabolite of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and its effects on 3-hydroxy-3-methylglutaryl-coenzyme A reductase in CHO-K1 cells.
    Swaminathan S; Pinkerton FD; Wilson WK; Schroepfer GJ
    Chem Phys Lipids; 1992 May; 61(3):235-42. PubMed ID: 1525963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Inhibitors of sterol synthesis: effects of a 7 alpha-alkyl analog of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in cultured mammalian cells and on serum cholesterol levels and other parameters in rats.
    Siddiqui AU; Gerst N; Kim LJ; Pinkerton FD; Kisic A; Wilson WK; Schroepfer GJ
    Chem Phys Lipids; 1994 Apr; 70(2):163-78. PubMed ID: 8033288
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibitors of sterol synthesis. Chemical synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholesta-8(14),24-dien-15-one, 3 beta,25-dihydroxy-5 alpha-cholest-8(14)-en-15-one, and 3 beta,24-dihydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Swaminathan S; Pinkerton FD; Numazawa S; Wilson WK; Schroepfer GJ
    J Lipid Res; 1992 Oct; 33(10):1503-15. PubMed ID: 1431575
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibitors of sterol synthesis. Chemical syntheses and spectral properties of 26-oxygenated derivatives of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Siddiqui AU; Wilson WK; Ruecker KE; Pinkerton FD; Schroepfer GJ
    Chem Phys Lipids; 1992 Nov; 63(1-2):77-90. PubMed ID: 1486662
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Sterol synthesis. Synthesis of 3 beta-hydroxy-25,26,26,26,27,27,27-heptafluorocholest-5-en-7-one and its effects on HMG-CoA reductase activity in Chinese hamster ovary cells, on ACAT activity in rat jejunal microsomes, and serum cholesterol levels in rats.
    Carroll JN; Pinkerton FD; Su X; Gerst N; Wilson WK; Schroepfer GJ
    Chem Phys Lipids; 1998 Aug; 94(2):209-25. PubMed ID: 9779586
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3 beta-hydroxy-5 alpha-cholestan-15-one and its 17 beta-epimer and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity.
    Siddiqui AU; Wilson WK; Parish EJ; Gerst N; Pinkerton FD; Schroepfer GJ
    Chem Phys Lipids; 1994 Oct; 74(1):1-15. PubMed ID: 7820900
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibitors of sterol synthesis. Chemical synthesis of 7 alpha-ethyl and 16 alpha-ethyl derivatives of delta 8(14)-15-oxygenated sterols and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase in CHO-K1 cells.
    Kim HS; Wilson WK; Kirkpatrick ND; Pinkerton FD; Swaminathan S; Hylarides MD; Schroepfer GJ
    Chem Phys Lipids; 1992 Jul; 62(1):55-67. PubMed ID: 1423803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of various oxygenated sterols on cellular sterol biosynthesis in Chinese hamster lung cells resistant to 25-hydroxycholesterol.
    Cavenee WK; Gibbons GF; Chen HW; Kandutsch AA
    Biochim Biophys Acta; 1979 Nov; 575(2):255-65. PubMed ID: 508785
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Synergistic action of two oxysterols in the lowering of HMG-CoA reductase activity in CHO-K1 cells.
    Pinkerton FD; Pelley RP; Schroepfer GJ
    Biochem Biophys Res Commun; 1992 Jul; 186(1):569-73. PubMed ID: 1632792
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sterol synthesis in variant Chinese hamster lung cells selected for resistance to 25-hydroxycholesterol. Cross-resistance to 7-ketocholesterol, 20alpha-hydroxycholesterol, and serum.
    Chen HW; Cavenee WK; Kandutsch AA
    J Biol Chem; 1979 Feb; 254(3):715-20. PubMed ID: 762093
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibitors of sterol synthesis. Characterization of beta,gamma-unsaturated analogs of 3 beta-hydroxy-5 alpha-cholest-8(14)-en-15-one and their effects on 3-hydroxy-3-methylglutaryl coenzyme A reductase activity in CHO-K1 cells.
    Wilson WK; Wheeler ME; Pinkerton FD; St Pyrek J; Schroepfer GJ
    J Lipid Res; 1991 Jul; 32(7):1215-27. PubMed ID: 1940644
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Treatment of CHO-K1 cells with 25-hydroxycholesterol produces a more rapid loss of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity than can be accounted for by enzyme turnover.
    von Gunten CF; Sinensky M
    Biochim Biophys Acta; 1989 Feb; 1001(2):218-24. PubMed ID: 2917146
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Down-regulation of mammalian 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with highly purified liposomal cholesterol.
    Plemenitas A; Watson JA
    Eur J Biochem; 1999 Dec; 266(2):317-26. PubMed ID: 10561571
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Inhibitors of sterol synthesis. A highly efficient and specific side-chain oxidation of 3 beta-acetoxy-5 alpha-cholest-8(14)-en-15-one for construction of metabolites and analogs of the 15-ketosterol.
    Herz JE; Swaminathan S; Pinkerton FD; Wilson WK; Schroepfer GJ
    J Lipid Res; 1992 Apr; 33(4):579-98. PubMed ID: 1527481
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Inhibitors of sterol synthesis. Synthesis and spectral properties of 3 beta-hydroxy-24-dimethylamino-5 alpha-chol-8(14)-en-15-one and its effects on HMG-CoA reductase activity in CHO-K1 cells.
    Herz JE; Wilson WK; Pinkerton FD; Schroepfer GJ
    Chem Phys Lipids; 1991 Nov; 60(1):61-9. PubMed ID: 1813179
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Defective regulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase in a somatic cell mutant.
    Sinensky M; Duwe G; Pinkerton F
    J Biol Chem; 1979 Jun; 254(11):4482-6. PubMed ID: 438201
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of sterol biosynthesis and of 3-hydroxy-3-methylglutaryl-coenzyme A reductase activity in cultured cells by progesterone.
    Panini SR; Gupta A; Sexton RC; Parish EJ; Rudney H
    J Biol Chem; 1987 Oct; 262(30):14435-40. PubMed ID: 3667583
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.