164 related articles for article (PubMed ID: 8075065)
1. Kinetics, stoichiometry, and identification of the reactive thiolate in the inactivation of UDP-GlcNAc enolpyruvoyl transferase by the antibiotic fosfomycin.
Marquardt JL; Brown ED; Lane WS; Haley TM; Ichikawa Y; Wong CH; Walsh CT
Biochemistry; 1994 Sep; 33(35):10646-51. PubMed ID: 8075065
[TBL] [Abstract][Full Text] [Related]
2. Structure of UDP-N-acetylglucosamine enolpyruvyl transferase, an enzyme essential for the synthesis of bacterial peptidoglycan, complexed with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Skarzynski T; Mistry A; Wonacott A; Hutchinson SE; Kelly VA; Duncan K
Structure; 1996 Dec; 4(12):1465-74. PubMed ID: 8994972
[TBL] [Abstract][Full Text] [Related]
3. Detection and characterization of a phospholactoyl-enzyme adduct in the reaction catalyzed by UDP-N-acetylglucosamine enolpyruvoyl transferase, MurZ.
Brown ED; Marquardt JL; Lee JP; Walsh CT; Anderson KS
Biochemistry; 1994 Sep; 33(35):10638-45. PubMed ID: 8075064
[TBL] [Abstract][Full Text] [Related]
4. Characterization of a Cys115 to Asp substitution in the Escherichia coli cell wall biosynthetic enzyme UDP-GlcNAc enolpyruvyl transferase (MurA) that confers resistance to inactivation by the antibiotic fosfomycin.
Kim DH; Lees WJ; Kempsell KE; Lane WS; Duncan K; Walsh CT
Biochemistry; 1996 Apr; 35(15):4923-8. PubMed ID: 8664284
[TBL] [Abstract][Full Text] [Related]
5. Studies on the conformational changes in the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine enolpyruvyltransferase (MurA).
Schönbrunn E; Svergun DI; Amrhein N; Koch MH
Eur J Biochem; 1998 Apr; 253(2):406-12. PubMed ID: 9654090
[TBL] [Abstract][Full Text] [Related]
6. Evidence that the reaction of the UDP-N-acetylglucosamine 1-carboxyvinyltransferase proceeds through the O-phosphothioketal of pyruvic acid bound to Cys115 of the enzyme.
Wanke C; Amrhein N
Eur J Biochem; 1993 Dec; 218(3):861-70. PubMed ID: 8281938
[TBL] [Abstract][Full Text] [Related]
7. Structure of MurA (UDP-N-acetylglucosamine enolpyruvyl transferase) from Vibrio fischeri in complex with substrate UDP-N-acetylglucosamine and the drug fosfomycin.
Bensen DC; Rodriguez S; Nix J; Cunningham ML; Tari LW
Acta Crystallogr Sect F Struct Biol Cryst Commun; 2012 Apr; 68(Pt 4):382-5. PubMed ID: 22505403
[TBL] [Abstract][Full Text] [Related]
8. The fungal product terreic acid is a covalent inhibitor of the bacterial cell wall biosynthetic enzyme UDP-N-acetylglucosamine 1-carboxyvinyltransferase (MurA) .
Han H; Yang Y; Olesen SH; Becker A; Betzi S; Schönbrunn E
Biochemistry; 2010 May; 49(19):4276-82. PubMed ID: 20392080
[TBL] [Abstract][Full Text] [Related]
9. Crystal structure of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin.
Yoon HJ; Lee SJ; Mikami B; Park HJ; Yoo J; Suh SW
Proteins; 2008 May; 71(2):1032-7. PubMed ID: 18247346
[No Abstract] [Full Text] [Related]
10. Evidence that the fosfomycin target Cys115 in UDP-N-acetylglucosamine enolpyruvyl transferase (MurA) is essential for product release.
Eschenburg S; Priestman M; Schönbrunn E
J Biol Chem; 2005 Feb; 280(5):3757-63. PubMed ID: 15531591
[TBL] [Abstract][Full Text] [Related]
11. Lysine 22 in UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae is crucial for enzymatic activity and the formation of covalent adducts with the substrate phosphoenolpyruvate and the antibiotic fosfomycin.
Samland AK; Amrhein N; Macheroux P
Biochemistry; 1999 Oct; 38(40):13162-9. PubMed ID: 10529188
[TBL] [Abstract][Full Text] [Related]
12. Crystallization and preliminary X-ray crystallographic analysis of UDP-N-acetylglucosamine enolpyruvyl transferase from Haemophilus influenzae in complex with UDP-N-acetylglucosamine and fosfomycin.
Yoon HJ; Ku MJ; Ahn HJ; Lee BI; Mikami B; Suh SW
Mol Cells; 2005 Jun; 19(3):398-401. PubMed ID: 15995357
[TBL] [Abstract][Full Text] [Related]
13. Cloning and sequencing of Escherichia coli murZ and purification of its product, a UDP-N-acetylglucosamine enolpyruvyl transferase.
Marquardt JL; Siegele DA; Kolter R; Walsh CT
J Bacteriol; 1992 Sep; 174(17):5748-52. PubMed ID: 1512209
[TBL] [Abstract][Full Text] [Related]
14. Evidence of kinetic control of ligand binding and staged product release in MurA (enolpyruvyl UDP-GlcNAc synthase)-catalyzed reactions .
Jackson SG; Zhang F; Chindemi P; Junop MS; Berti PJ
Biochemistry; 2009 Dec; 48(49):11715-23. PubMed ID: 19899805
[TBL] [Abstract][Full Text] [Related]
15. Determination of the pKa value of C115 in MurA (UDP-N-acetylglucosamine enolpyruvyltransferase) from Enterobacter cloacae.
Krekel F; Samland AK; Macheroux P; Amrhein N; Evans JN
Biochemistry; 2000 Oct; 39(41):12671-7. PubMed ID: 11027147
[TBL] [Abstract][Full Text] [Related]
16. Role of K22 and R120 in the covalent binding of the antibiotic fosfomycin and the substrate-induced conformational change in UDP-N-acetylglucosamine enolpyruvyl transferase.
Thomas AM; Ginj C; Jelesarov I; Amrhein N; Macheroux P
Eur J Biochem; 2004 Jul; 271(13):2682-90. PubMed ID: 15206933
[TBL] [Abstract][Full Text] [Related]
17. Asparagine 23 and aspartate 305 are essential residues in the active site of UDP-N-acetylglucosamine enolpyruvyl transferase from Enterobacter cloacae.
Samland AK; Etezady-Esfarjani T; Amrhein N; Macheroux P
Biochemistry; 2001 Feb; 40(6):1550-9. PubMed ID: 11327813
[TBL] [Abstract][Full Text] [Related]
18. Effect of phosphoenolpyruvate analogs on the activity of enoylpyruvate transferase and the effect of UDP-N-acetylglucosamine on the reactivity of the active site SH group.
Anwar RA; Vlaovic M
Biochim Biophys Acta; 1980 Dec; 616(2):389-94. PubMed ID: 7213646
[TBL] [Abstract][Full Text] [Related]
19. Lyme disease enolpyruvyl-UDP-GlcNAc synthase: fosfomycin-resistant MurA from Borrelia burgdorferi, a fosfomycin-sensitive mutant, and the catalytic role of the active site Asp.
Jiang S; Gilpin ME; Attia M; Ting YL; Berti PJ
Biochemistry; 2011 Mar; 50(12):2205-12. PubMed ID: 21294548
[TBL] [Abstract][Full Text] [Related]
20. Establishment of a five-enzyme cell-free cascade for the synthesis of uridine diphosphate N-acetylglucosamine.
Mahour R; Klapproth J; Rexer TFT; Schildbach A; Klamt S; Pietzsch M; Rapp E; Reichl U
J Biotechnol; 2018 Oct; 283():120-129. PubMed ID: 30044949
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
