172 related articles for article (PubMed ID: 8075371)
1. Conjugation of glutathione and other thiols with bioreductively activated mitomycin C. Effect of thiols on the reductive activation rate.
Sharma M; Tomasz M
Chem Res Toxicol; 1994; 7(3):390-400. PubMed ID: 8075371
[TBL] [Abstract][Full Text] [Related]
2. Mitomycin C-DNA adducts generated by DT-diaphorase. Revised mechanism of the enzymatic reductive activation of mitomycin C.
Suresh Kumar G; Lipman R; Cummings J; Tomasz M
Biochemistry; 1997 Nov; 36(46):14128-36. PubMed ID: 9369485
[TBL] [Abstract][Full Text] [Related]
3. Effects of glutathione on alkylation and cross-linking of DNA by mitomycin C. Isolation of a ternary glutathione-mitomycin-DNA adduct.
Sharma M; He QY; Tomasz M
Chem Res Toxicol; 1994; 7(3):401-7. PubMed ID: 8075372
[TBL] [Abstract][Full Text] [Related]
4. Evaluation of the effect of oxygen exposure on human liver microsomal metabolism of mitomycin C in the presence of glutathione using liquid chromatography-quadrupole time of flight mass spectrometry.
Lang W; Caldwell GW; Masucci JA
Anal Biochem; 2005 Aug; 343(2):268-76. PubMed ID: 16005424
[TBL] [Abstract][Full Text] [Related]
5. Role of NADPH:cytochrome c reductase and DT-diaphorase in the biotransformation of mitomycin C1.
Keyes SR; Fracasso PM; Heimbrook DC; Rockwell S; Sligar SG; Sartorelli AC
Cancer Res; 1984 Dec; 44(12 Pt 1):5638-43. PubMed ID: 6437671
[TBL] [Abstract][Full Text] [Related]
6. Reductive activation of mitomycin C by thiols: kinetics, mechanism, and biological implications.
Paz MM
Chem Res Toxicol; 2009 Oct; 22(10):1663-8. PubMed ID: 19791750
[TBL] [Abstract][Full Text] [Related]
7. Identification of multi-S-substituted conjugates of hydroquinone by HPLC-coulometric electrode array analysis and mass spectroscopy.
Hill BA; Kleiner HE; Ryan EA; Dulik DM; Monks TJ; Lau SS
Chem Res Toxicol; 1993; 6(4):459-69. PubMed ID: 8374043
[TBL] [Abstract][Full Text] [Related]
8. In vivo effects of N-acetylcysteine on glutathione metabolism and on the biotransformation of carcinogenic and/or mutagenic compounds.
De Flora S; Bennicelli C; Camoirano A; Serra D; Romano M; Rossi GA; Morelli A; De Flora A
Carcinogenesis; 1985 Dec; 6(12):1735-45. PubMed ID: 3905042
[TBL] [Abstract][Full Text] [Related]
9. Selective activation of mitomycin A by thiols to form DNA cross-links and monoadducts: biochemical basis for the modulation of mitomycin cytotoxicity by the quinone redox potential.
Paz MM; Das A; Palom Y; He QY; Tomasz M
J Med Chem; 2001 Aug; 44(17):2834-42. PubMed ID: 11495594
[TBL] [Abstract][Full Text] [Related]
10. Identification of intermediate pathways of 4-hydroxynonenal metabolism in the rat.
Alary J; Fernandez Y; Debrauwer L; Perdu E; Guéraud F
Chem Res Toxicol; 2003 Mar; 16(3):320-7. PubMed ID: 12641432
[TBL] [Abstract][Full Text] [Related]
11. Identification of N-acetylcysteine conjugates of 1,2-dibromo-3-chloropropane: evidence for cytochrome P450 and glutathione mediated bioactivation pathways.
Weber GL; Steenwyk RC; Nelson SD; Pearson PG
Chem Res Toxicol; 1995 Jun; 8(4):560-73. PubMed ID: 7548736
[TBL] [Abstract][Full Text] [Related]
12. Nonenzymatic reductive activation of 7-N-((2-([2-(gamma-L-glutamylamino)ethyl]dithio)ethyl))mitomycin C by thiol molecules: a novel mitomycin C derivative effective on mitomycin C-resistant tumor cells.
Lee JH; Naito M; Tsuruo T
Cancer Res; 1994 May; 54(9):2398-403. PubMed ID: 8162587
[TBL] [Abstract][Full Text] [Related]
13. Mechanistic studies on the metabolic scission of thiazolidinedione derivatives to acyclic thiols.
Reddy VB; Karanam BV; Gruber WL; Wallace MA; Vincent SH; Franklin RB; Baillie TA
Chem Res Toxicol; 2005 May; 18(5):880-8. PubMed ID: 15892582
[TBL] [Abstract][Full Text] [Related]
14. Identification of a novel glutathione conjugate of flutamide in incubations with human liver microsomes.
Kang P; Dalvie D; Smith E; Zhou S; Deese A
Drug Metab Dispos; 2007 Jul; 35(7):1081-8. PubMed ID: 17403914
[TBL] [Abstract][Full Text] [Related]
15. Covalent thiol adducts arising from reactive intermediates of cocaine biotransformation.
Schneider KJ; DeCaprio AP
Chem Res Toxicol; 2013 Nov; 26(11):1755-64. PubMed ID: 24112049
[TBL] [Abstract][Full Text] [Related]
16. Bioreductive activation of mitomycin C by DT-diaphorase.
Siegel D; Beall H; Senekowitsch C; Kasai M; Arai H; Gibson NW; Ross D
Biochemistry; 1992 Sep; 31(34):7879-85. PubMed ID: 1510975
[TBL] [Abstract][Full Text] [Related]
17. Metabolism of bioreductive antitumor compounds by purified rat and human DT-diaphorases.
Beall HD; Mulcahy RT; Siegel D; Traver RD; Gibson NW; Ross D
Cancer Res; 1994 Jun; 54(12):3196-201. PubMed ID: 8205540
[TBL] [Abstract][Full Text] [Related]
18. Thiol oxidation coupled to DT-diaphorase-catalysed reduction of diaziquone. Reductive and oxidative pathways of diaziquone semiquinone modulated by glutathione and superoxide dismutase.
Ordoñez ID; Cadenas E
Biochem J; 1992 Sep; 286 ( Pt 2)(Pt 2):481-90. PubMed ID: 1530580
[TBL] [Abstract][Full Text] [Related]
19. Study of the redox properties of naphthazarin (5,8-dihydroxy-1,4-naphthoquinone) and its glutathionyl conjugate in biological reactions: one- and two-electron enzymatic reduction.
Ollinger K; Llopis J; Cadenas E
Arch Biochem Biophys; 1989 Dec; 275(2):514-30. PubMed ID: 2512857
[TBL] [Abstract][Full Text] [Related]
20. Mitomycin C linked to DNA minor groove binding agents: synthesis, reductive activation, DNA binding and cross-linking properties and in vitro antitumor activity.
Paz MM; Das TA; Tomasz M
Bioorg Med Chem; 1999 Dec; 7(12):2713-26. PubMed ID: 10658576
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
