BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

221 related articles for article (PubMed ID: 8081359)

  • 41. The T341C (Ile114Thr) polymorphism of N-acetyltransferase 2 yields slow acetylator phenotype by enhanced protein degradation.
    Zang Y; Zhao S; Doll MA; States JC; Hein DW
    Pharmacogenetics; 2004 Nov; 14(11):717-23. PubMed ID: 15564878
    [TBL] [Abstract][Full Text] [Related]  

  • 42. Genotype/phenotype discordance for human arylamine N-acetyltransferase (NAT2) reveals a new slow-acetylator allele common in African-Americans.
    Bell DA; Taylor JA; Butler MA; Stephens EA; Wiest J; Brubaker LH; Kadlubar FF; Lucier GW
    Carcinogenesis; 1993 Aug; 14(8):1689-92. PubMed ID: 8102597
    [TBL] [Abstract][Full Text] [Related]  

  • 43. Functional characterization of human N-acetyltransferase 2 (NAT2) single nucleotide polymorphisms.
    Fretland AJ; Leff MA; Doll MA; Hein DW
    Pharmacogenetics; 2001 Apr; 11(3):207-15. PubMed ID: 11337936
    [TBL] [Abstract][Full Text] [Related]  

  • 44. Polymorphic arylamine N-acetyltransferase (NAT2) genes in children with insulin-dependent diabetes mellitus.
    Mrozikiewicz PM; Drakoulis N; Roots I
    Clin Pharmacol Ther; 1994 Dec; 56(6 Pt 1):626-34. PubMed ID: 7995004
    [TBL] [Abstract][Full Text] [Related]  

  • 45. Site-directed mutagenesis of recombinant human arylamine N-acetyltransferase expressed in Escherichia coli. Evidence for direct involvement of Cys68 in the catalytic mechanism of polymorphic human NAT2.
    Dupret JM; Grant DM
    J Biol Chem; 1992 Apr; 267(11):7381-5. PubMed ID: 1559981
    [TBL] [Abstract][Full Text] [Related]  

  • 46. Purification of hepatic polymorphic arylamine N-acetyltransferase from homozygous rapid acetylator inbred hamster: identity with polymorphic N-hydroxyarylamine-O-acetyltransferase.
    Trinidad A; Hein DW; Rustan TD; Ferguson RJ; Miller LS; Bucher KD; Kirlin WG; Ogolla F; Andrews AF
    Cancer Res; 1990 Dec; 50(24):7942-9. PubMed ID: 2253236
    [TBL] [Abstract][Full Text] [Related]  

  • 47. NAT2, an essential gene encoding methionine N alpha-acetyltransferase in the yeast Saccharomyces cerevisiae.
    Kulkarni MS; Sherman F
    J Biol Chem; 1994 May; 269(18):13141-7. PubMed ID: 8175741
    [TBL] [Abstract][Full Text] [Related]  

  • 48. Arylamine N-acetyltransferases. Expression in Escherichia coli, purification, and substrate specificities of recombinant hamster monomorphic and polymorphic isozymes.
    Wagner CR; Bergstrom CP; Koning KR; Hanna PE
    Drug Metab Dispos; 1996 Feb; 24(2):245-53. PubMed ID: 8742238
    [TBL] [Abstract][Full Text] [Related]  

  • 49. The S-acetyl coenzyme A-dependent metabolic activation of the carcinogen N-hydroxy-2-aminofluorene by human liver cytosol and its relationship to the aromatic amine N-acetyltransferase phenotype.
    Flammang TJ; Yamazoe Y; Guengerich FP; Kadlubar FF
    Carcinogenesis; 1987 Dec; 8(12):1967-70. PubMed ID: 3677322
    [TBL] [Abstract][Full Text] [Related]  

  • 50. Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2.
    Walraven JM; Zang Y; Trent JO; Hein DW
    Curr Drug Metab; 2008 Jul; 9(6):471-86. PubMed ID: 18680467
    [TBL] [Abstract][Full Text] [Related]  

  • 51. Genotyping of the polymorphic N-acetyltransferase (NAT2*) gene locus in two native African populations.
    Deloménie C; Sica L; Grant DM; Krishnamoorthy R; Dupret JM
    Pharmacogenetics; 1996 Apr; 6(2):177-85. PubMed ID: 9156695
    [TBL] [Abstract][Full Text] [Related]  

  • 52. Effects of single nucleotide polymorphisms in human N-acetyltransferase 2 on metabolic activation (O-acetylation) of heterocyclic amine carcinogens.
    Hein DW; Fretland AJ; Doll MA
    Int J Cancer; 2006 Sep; 119(5):1208-11. PubMed ID: 16570281
    [TBL] [Abstract][Full Text] [Related]  

  • 53. N-Acetyltransferase-2 genetic polymorphism, well-done meat intake, and breast cancer risk among postmenopausal women.
    Deitz AC; Zheng W; Leff MA; Gross M; Wen WQ; Doll MA; Xiao GH; Folsom AR; Hein DW
    Cancer Epidemiol Biomarkers Prev; 2000 Sep; 9(9):905-10. PubMed ID: 11008907
    [TBL] [Abstract][Full Text] [Related]  

  • 54. 2-Amino-3,8-dimethylimidazo-[4,5-f]quinoxaline-induced DNA adduct formation and mutagenesis in DNA repair-deficient Chinese hamster ovary cells expressing human cytochrome P4501A1 and rapid or slow acetylator N-acetyltransferase 2.
    Bendaly J; Zhao S; Neale JR; Metry KJ; Doll MA; States JC; Pierce WM; Hein DW
    Cancer Epidemiol Biomarkers Prev; 2007 Jul; 16(7):1503-9. PubMed ID: 17627018
    [TBL] [Abstract][Full Text] [Related]  

  • 55. Acetylator status and N-acetyltransferase 2 gene polymorphisms; phenotype-genotype correlation with the sulfamethazine test.
    Taja-Chayeb L; González-Fierro A; Miguez-Muñoz C; Trejo-Becerril C; Cruz-Hernandez Ede L; Cantu D; Agundez JA; Vidal-Millan S; Gutierrez O; Dueñas-González A
    Pharmacogenet Genomics; 2011 Dec; 21(12):894-901. PubMed ID: 21946899
    [TBL] [Abstract][Full Text] [Related]  

  • 56. The structure and characteristics of a fourth allele of polymorphic N-acetyltransferase gene found in the Japanese population.
    Abe M; Deguchi T; Suzuki T
    Biochem Biophys Res Commun; 1993 Mar; 191(3):811-6. PubMed ID: 8466518
    [TBL] [Abstract][Full Text] [Related]  

  • 57. Association of XRCC1, XRCC3, and NAT2 polymorphisms with the risk of oral submucous fibrosis among eastern Indian population.
    Mukherjee S; Bhowmik AD; Roychoudhury P; Mukhopadhyay K; Ray JG; Chaudhuri K
    J Oral Pathol Med; 2012 Apr; 41(4):292-302. PubMed ID: 22092501
    [TBL] [Abstract][Full Text] [Related]  

  • 58. [Biochemical, molecular genetic and ecogenetic studies of polymorphic arylamine N-acetyltransferase (NAT2) in the brain].
    Ogawa M
    Fukuoka Igaku Zasshi; 1999 Apr; 90(4):118-31. PubMed ID: 10361374
    [TBL] [Abstract][Full Text] [Related]  

  • 59. Study of the role of the highly conserved residues Arg9 and Arg64 in the catalytic function of human N-acetyltransferases NAT1 and NAT2 by site-directed mutagenesis.
    Deloménie C; Goodfellow GH; Krishnamoorthy R; Grant DM; Dupret JM
    Biochem J; 1997 Apr; 323 ( Pt 1)(Pt 1):207-15. PubMed ID: 9173883
    [TBL] [Abstract][Full Text] [Related]  

  • 60. Primary structure and molecular basis of polymorphic appearance of an acetyltransferase (AT-II)* in hamsters.
    Nagata K; Ozawa S; Miyata M; Shimada M; Yamazoe Y; Kato R
    Pharmacogenetics; 1994 Apr; 4(2):91-100. PubMed ID: 7915937
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 12.