214 related articles for article (PubMed ID: 8086425)
1. Phosphorus-31 nuclear magnetic resonance studies of complexes of thymidylate synthase.
Connick TJ; Reilly RT; Dunlap RB; Ellis PD
Biochim Biophys Acta; 1994 Sep; 1208(1):118-26. PubMed ID: 8086425
[TBL] [Abstract][Full Text] [Related]
2. A stable binary complex between Leishmania major thymidylate synthase and the substrate deoxyuridylate. A slow-binding interaction.
Garvey EP; Santi DV
J Biol Chem; 1987 Jul; 262(19):9068-74. PubMed ID: 3597407
[TBL] [Abstract][Full Text] [Related]
3. Deoxyuridylate effects on thymidylate synthase-5-fluorodeoxyuridylate-folate ternary complex formation.
Spears CP; Hayes AA; Shahinian AH; Danenberg PV; Frösing R; Gustavsson BG
Biochem Pharmacol; 1989 Sep; 38(18):2985-93. PubMed ID: 2783153
[TBL] [Abstract][Full Text] [Related]
4. Fluorine-19 nuclear magnetic resonance studies of binary and ternary complexes of thymidylate synthase utilizing a fluorine-labeled folate analogue.
Connick TJ; Reilly RT; Dunlap RB; Ellis PD
Biochemistry; 1993 Sep; 32(38):9888-95. PubMed ID: 8399157
[TBL] [Abstract][Full Text] [Related]
5. Evidence for the existence of covalent nucleotide-thymidylate synthase complexes, identification of site of attachment, and enhancement by folates.
Moore MA; Ahmed F; Dunlap RB
J Biol Chem; 1986 Sep; 261(27):12745-9. PubMed ID: 3745210
[TBL] [Abstract][Full Text] [Related]
6. Spectroscopic studies of ternary complexes of thymidylate synthetase, deoxyribonucleotides, and folate analogs.
Lockshin A; Mondal K; Danenberg PV
J Biol Chem; 1984 Sep; 259(18):11346-52. PubMed ID: 6236224
[TBL] [Abstract][Full Text] [Related]
7. The separate effects of E60Q in Lactobacillus casei thymidylate synthase delineate between mechanisms for formation of intermediates in catalysis.
Birdsall DL; Huang W; Santi DV; Stroud RM; Finer-Moore J
Protein Eng; 1998 Mar; 11(3):171-83. PubMed ID: 9613841
[TBL] [Abstract][Full Text] [Related]
8. Relationship of dUMP and free FdUMP pools to inhibition of thymidylate synthase by 5-fluorouracil.
Berger SH; Hakala MT
Mol Pharmacol; 1984 Mar; 25(2):303-9. PubMed ID: 6608049
[TBL] [Abstract][Full Text] [Related]
9. Structural Comparison of
Pozzi C; Ferrari S; Luciani R; Tassone G; Costi MP; Mangani S
Molecules; 2019 Mar; 24(7):. PubMed ID: 30935102
[TBL] [Abstract][Full Text] [Related]
10. Fluorine-19 nuclear magnetic resonance characterization of ternary complexes of folate derivatives, 5-fluorodeoxyuridylate and Lactobacillus.
Lewis CA; Ellis PD; Dunlap RB
Biochemistry; 1981 Apr; 20(8):2275-85. PubMed ID: 6786329
[TBL] [Abstract][Full Text] [Related]
11. Effect of polyglutamylation of 5,10-methylenetetrahydrofolate on the binding of 5-fluoro-2'-deoxyuridylate to thymidylate synthase purified from a human colon adenocarcinoma xenograft.
Radparvar S; Houghton PJ; Houghton JA
Biochem Pharmacol; 1989 Jan; 38(2):335-42. PubMed ID: 2914018
[TBL] [Abstract][Full Text] [Related]
12. Effect of halogen substitutions on dUMP to stability of thymidylate synthase/dUMP/mTHF ternary complex using molecular dynamics simulation.
Kaiyawet N; Rungrotmongkol T; Hannongbua S
J Chem Inf Model; 2013 Jun; 53(6):1315-23. PubMed ID: 23705822
[TBL] [Abstract][Full Text] [Related]
13. Quinazoline folate analogs inhibit the catalytic activity of thymidylate synthase but allow binding of 5-fluorodeoxyuridylate.
Keyomarsi K; Moran RG
J Biol Chem; 1990 Nov; 265(31):19163-9. PubMed ID: 2146271
[TBL] [Abstract][Full Text] [Related]
14. The complex of the anti-cancer therapeutic, BW1843U89, with thymidylate synthase at 2.0 A resolution: implications for a new mode of inhibition.
Stout TJ; Stroud RM
Structure; 1996 Jan; 4(1):67-77. PubMed ID: 8805515
[TBL] [Abstract][Full Text] [Related]
15. Kinetic scheme for thymidylate synthase from Escherichia coli: determination from measurements of ligand binding, primary and secondary isotope effects, and pre-steady-state catalysis.
Spencer HT; Villafranca JE; Appleman JR
Biochemistry; 1997 Apr; 36(14):4212-22. PubMed ID: 9100016
[TBL] [Abstract][Full Text] [Related]
16. Binding of the anticancer drug ZD1694 to E. coli thymidylate synthase: assessing specificity and affinity.
Rutenber EE; Stroud RM
Structure; 1996 Nov; 4(11):1317-24. PubMed ID: 8939755
[TBL] [Abstract][Full Text] [Related]
17. Stereochemical mechanism of action for thymidylate synthase based on the X-ray structure of the covalent inhibitory ternary complex with 5-fluoro-2'-deoxyuridylate and 5,10-methylenetetrahydrofolate.
Matthews DA; Villafranca JE; Janson CA; Smith WW; Welsh K; Freer S
J Mol Biol; 1990 Aug; 214(4):937-48. PubMed ID: 2201779
[TBL] [Abstract][Full Text] [Related]
18. Properties of a defined mutant of Escherichia coli thymidylate synthase.
Maley GF; Maley F
J Biol Chem; 1988 Jun; 263(16):7620-7. PubMed ID: 3286637
[TBL] [Abstract][Full Text] [Related]
19. The effect of derivatives of folic acid on the fluorodeoxyuridylate-thymidylate synthetase covalent complex in human colon xenografts.
Houghton JA; Schmidt C; Houghton PJ
Eur J Cancer Clin Oncol; 1982 Apr; 18(4):347-54. PubMed ID: 6889511
[TBL] [Abstract][Full Text] [Related]
20. Relative free energies of binding to thymidylate synthase of 2- and/or 4-thio and/or 5-fluoro analogues of dUMP.
Jarmuła A; Cieplak P; Leś A; Rode W
J Comput Aided Mol Des; 2003 Oct; 17(10):699-710. PubMed ID: 15068368
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
