129 related articles for article (PubMed ID: 8086670)
1. Inhibition of thymidine transport by 3'-azido-3'-deoxythymidine and its metabolites.
Zimmerman TP; Domin BA; Mahony WB
Oncol Res; 1993; 5(12):483-7. PubMed ID: 8086670
[TBL] [Abstract][Full Text] [Related]
2. Membrane permeation characteristics of 5'-modified thymidine analogs.
Domin BA; Mahony WB; Koszalka GW; Porter DJ; Hajian G; Zimmerman TP
Mol Pharmacol; 1992 May; 41(5):950-6. PubMed ID: 1588925
[TBL] [Abstract][Full Text] [Related]
3. Comparative effects of 3'-azido-3'-deoxythymidine and its metabolite 3'-amino-3'-deoxythymidine on hemoglobin synthesis in K-562 human leukemia cells.
Weidner DA; Bridges EG; Cretton EM; Sommadossi JP
Mol Pharmacol; 1992 Feb; 41(2):252-8. PubMed ID: 1538705
[TBL] [Abstract][Full Text] [Related]
4. Catabolism of 3'-azido-3'-deoxythymidine in hepatocytes and liver microsomes, with evidence of formation of 3'-amino-3'-deoxythymidine, a highly toxic catabolite for human bone marrow cells.
Cretton EM; Xie MY; Bevan RJ; Goudgaon NM; Schinazi RF; Sommadossi JP
Mol Pharmacol; 1991 Feb; 39(2):258-66. PubMed ID: 1996084
[TBL] [Abstract][Full Text] [Related]
5. In vivo biodistribution, pharmacokinetic parameters, and brain uptake of 5-halo-y-methoxy(or ethoxy)-5,6-dihydro-3'-azido-3'-deoxythymidine diastereomers as potential prodrugs of 3'-azido-3'-deoxythymidine.
Wang L; Morin KW; Kumar R; Cheraghali M; Todd KG; Baker GB; Knaus EE; Wiebe LI
J Med Chem; 1996 Feb; 39(4):826-33. PubMed ID: 8632406
[TBL] [Abstract][Full Text] [Related]
6. Probing the mechanism of action and decomposition of amino acid phosphomonoester amidates of antiviral nucleoside prodrugs.
McIntee EJ; Remmel RP; Schinazi RF; Abraham TW; Wagner CR
J Med Chem; 1997 Oct; 40(21):3323-31. PubMed ID: 9341906
[TBL] [Abstract][Full Text] [Related]
7. 3'-Azido-3'-deoxythymidine cytotoxicity and metabolism in the human colon tumor cell line HCT-8.
Darnowski JW; Goulette FA
Biochem Pharmacol; 1994 Nov; 48(9):1797-805. PubMed ID: 7980649
[TBL] [Abstract][Full Text] [Related]
8. AZT: a biochemical response modifier of methotrexate and 5-fluorouracil cytotoxicity in human ovarian and pancreatic carcinoma cells.
Weber G; Nagai M; Prajda N; Nakamura H; Szekeres T; Olah E
Cancer Commun; 1991 Apr; 3(4):127-32. PubMed ID: 2025497
[TBL] [Abstract][Full Text] [Related]
9. Comparative metabolism of 3'-azido-3'-deoxythymidine in cultured hepatocytes from rats, dogs, monkeys, and humans.
Nicolas F; De Sousa G; Thomas P; Placidi M; Lorenzon G; Rahmani R
Drug Metab Dispos; 1995 Mar; 23(3):308-13. PubMed ID: 7628294
[TBL] [Abstract][Full Text] [Related]
10. Azidothymidine and dipyridamole as biochemical response modifiers: synergism with methotrexate and 5-fluorouracil in human colon and pancreatic carcinoma cells.
Zhen YS; Taniki T; Weber G
Oncol Res; 1992; 4(2):73-8. PubMed ID: 1596584
[TBL] [Abstract][Full Text] [Related]
11. Effect of anticancer drugs on the glucuronidation of 3'-azido-3'-deoxythymidine in human liver microsomes.
Rajaonarison JF; Lacarelle B; Catalin J; Durand A; Cano JP
Drug Metab Dispos; 1993; 21(5):823-9. PubMed ID: 7902243
[TBL] [Abstract][Full Text] [Related]
12. Pharmacokinetics of 3'-azido-3'-deoxythymidine and its catabolites and interactions with probenecid in rhesus monkeys.
Cretton EM; Schinazi RF; McClure HM; Anderson DC; Sommadossi JP
Antimicrob Agents Chemother; 1991 May; 35(5):801-7. PubMed ID: 1854160
[TBL] [Abstract][Full Text] [Related]
13. Comparative metabolism of the antiviral dimer 3'-azido-3'-deoxythymidine-P-2',3'-dideoxyinosine and the monomers zidovudine and didanosine by rat, monkey, and human hepatocytes.
Pan-Zhou XR; Cretton-Scott E; Zhou XJ; Xie MY; Rahmani R; Schinazi RF; Duchin K; Sommadossi JP
Antimicrob Agents Chemother; 1997 Nov; 41(11):2502-10. PubMed ID: 9371357
[TBL] [Abstract][Full Text] [Related]
14. Modulation of 3'-azido-3'-deoxythymidine catabolism by probenecid and acetaminophen in freshly isolated rat hepatocytes.
Cretton EM; Sommadossi JP
Biochem Pharmacol; 1991 Sep; 42(7):1475-80. PubMed ID: 1930271
[TBL] [Abstract][Full Text] [Related]
15. Synthesis and in vitro activity of long-chain 5'-O-[(alkoxycarbonyl)phosphinyl]-3'-azido-3'-deoxythymidines against wild-type and AZT- and foscarnet-resistant strains of HIV-1.
Rosowsky A; Fu H; Pai N; Mellors J; Richman DD; Hostetler KY
J Med Chem; 1997 Aug; 40(16):2482-90. PubMed ID: 9258355
[TBL] [Abstract][Full Text] [Related]
16. Azidothymidine inhibition of thymidine kinase and synergistic cytotoxicity with methotrexate and 5-fluorouracil in rat hepatoma and human colon cancer cells.
Weber G; Ichikawa S; Nagai M; Natsumeda Y
Cancer Commun; 1990; 2(4):129-33. PubMed ID: 2369552
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of mammalian DNA polymerase-associated 3' to 5' exonuclease activity by 5'-monophosphates of 3'-azido-3'-deoxythymidine and 3'-amino-3'-deoxythymidine.
Bridges EG; Faraj A; Sommadossi JP
Biochem Pharmacol; 1993 Apr; 45(8):1571-6. PubMed ID: 8387298
[TBL] [Abstract][Full Text] [Related]
18. Interaction of 2'-halogeno-2'-deoxyuridines with the human erythrocyte nucleoside transport mechanism.
Gati WP; Knaus EE; Wiebe LI
Mol Pharmacol; 1983 Jan; 23(1):146-52. PubMed ID: 6223203
[TBL] [Abstract][Full Text] [Related]
19. Suppression of replication of multidrug-resistant HIV type 1 variants by combinations of thymidylate synthase inhibitors with zidovudine or stavudine.
Gao WY; Johns DG; Tanaka M; Mitsuya H
Mol Pharmacol; 1999 Mar; 55(3):535-40. PubMed ID: 10051538
[TBL] [Abstract][Full Text] [Related]
20. Electrochemical reduction products of azido nucleosides, including zidovudine (AZT): mechanisms and relevance to their intracellular metabolism.
Kawczyński W; Czochralska B; Shugar D
Acta Biochim Pol; 1993; 40(2):213-23. PubMed ID: 8212958
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
