133 related articles for article (PubMed ID: 8089099)
1. A model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Evidence for a second direct interaction between transmembrane helix 3 and TRH.
Perlman JH; Laakkonen L; Osman R; Gershengorn MC
J Biol Chem; 1994 Sep; 269(38):23383-6. PubMed ID: 8089099
[TBL] [Abstract][Full Text] [Related]
2. A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Experimental analysis and energy minimization of the complex between TRH and TRH receptor.
Perlman JH; Laakkonen LJ; Guarnieri F; Osman R; Gershengorn MC
Biochemistry; 1996 Jun; 35(24):7643-50. PubMed ID: 8672465
[TBL] [Abstract][Full Text] [Related]
3. Hydrogen bonding interaction of thyrotropin-releasing hormone (TRH) with transmembrane tyrosine 106 of the TRH receptor.
Perlman JH; Thaw CN; Laakkonen L; Bowers CY; Osman R; Gershengorn MC
J Biol Chem; 1994 Jan; 269(3):1610-3. PubMed ID: 8294406
[TBL] [Abstract][Full Text] [Related]
4. Role of the extracellular loops of the thyrotropin-releasing hormone receptor: evidence for an initial interaction with thyrotropin-releasing hormone.
Perlman JH; Colson AO; Jain R; Czyzewski B; Cohen LA; Osman R; Gershengorn MC
Biochemistry; 1997 Dec; 36(50):15670-6. PubMed ID: 9398295
[TBL] [Abstract][Full Text] [Related]
5. Interactions between conserved residues in transmembrane helices 1, 2, and 7 of the thyrotropin-releasing hormone receptor.
Perlman JH; Colson AO; Wang W; Bence K; Osman R; Gershengorn MC
J Biol Chem; 1997 May; 272(18):11937-42. PubMed ID: 9115256
[TBL] [Abstract][Full Text] [Related]
6. Identification of Asn289 as a ligand binding site in the rat thyrotropin-releasing hormone (THR) receptor as determined by complementary modifications in the ligand and receptor: a new model for THR binding.
Han B; Tashjian AH
Biochemistry; 1995 Oct; 34(41):13412-22. PubMed ID: 7577928
[TBL] [Abstract][Full Text] [Related]
7. Analysis of the role of transmembrane helix three of the thyrotropin-releasing hormone (TRH) receptor in directly binding TRH.
Perlman JH; Laakkonen L; Thaw CN; Osman R; Gershengorn MC
Trans Assoc Am Physicians; 1993; 106():162-7. PubMed ID: 8036739
[No Abstract] [Full Text] [Related]
8. A model of inverse agonist action at thyrotropin-releasing hormone receptor type 1: role of a conserved tryptophan in helix 6.
Lu X; Huang W; Worthington S; Drabik P; Osman R; Gershengorn MC
Mol Pharmacol; 2004 Nov; 66(5):1192-200. PubMed ID: 15306657
[TBL] [Abstract][Full Text] [Related]
9. A refined model of the thyrotropin-releasing hormone (TRH) receptor binding pocket. Novel mixed mode Monte Carlo/stochastic dynamics simulations of the complex between TRH and TRH receptor.
Laakkonen LJ; Guarnieri F; Perlman JH; Gershengorn MC; Osman R
Biochemistry; 1996 Jun; 35(24):7651-63. PubMed ID: 8672466
[TBL] [Abstract][Full Text] [Related]
10. Altered ligand dissociation rates in thyrotropin-releasing hormone receptors mutated in glutamine 105 of transmembrane helix III.
del Camino D; Barros F; Pardo LA; de la Peña P
Biochemistry; 1997 Mar; 36(11):3308-18. PubMed ID: 9116009
[TBL] [Abstract][Full Text] [Related]
11. A disulfide bonding interaction role for cysteines in the extracellular domain of the thyrotropin-releasing hormone receptor.
Cook JV; McGregor A; Lee T; Milligan G; Eidne KA
Endocrinology; 1996 Jul; 137(7):2851-8. PubMed ID: 8770906
[TBL] [Abstract][Full Text] [Related]
12. Static and dynamic roles of extracellular loops in G-protein-coupled receptors: a mechanism for sequential binding of thyrotropin-releasing hormone to its receptor.
Colson AO; Perlman JH; Smolyar A; Gershengorn MC; Osman R
Biophys J; 1998 Mar; 74(3):1087-100. PubMed ID: 9512011
[TBL] [Abstract][Full Text] [Related]
13. Thyrotropin-releasing hormone and its receptors--a hypothesis for binding and receptor activation.
Engel S; Gershengorn MC
Pharmacol Ther; 2007 Feb; 113(2):410-9. PubMed ID: 17123625
[TBL] [Abstract][Full Text] [Related]
14. Importance of extracellular domains for ligand binding in the thyrotropin-releasing hormone receptor.
Han B; Tashjian AH
Mol Endocrinol; 1995 Dec; 9(12):1708-19. PubMed ID: 8614407
[TBL] [Abstract][Full Text] [Related]
15. Synthesis, receptor binding, and activation studies of N(1)-alkyl-L-histidine containing thyrotropin-releasing hormone (TRH) analogues.
Kaur N; Monga V; Josan JS; Lu X; Gershengorn MC; Jain R
Bioorg Med Chem; 2006 Sep; 14(17):5981-8. PubMed ID: 16735122
[TBL] [Abstract][Full Text] [Related]
16. Thyrotropin-releasing hormone binding to the mouse pituitary receptor does not involve ionic interactions. A model for neutral peptide binding to G protein-coupled receptors.
Perlman JH; Nussenzveig DR; Osman R; Gershengorn MC
J Biol Chem; 1992 Dec; 267(34):24413-7. PubMed ID: 1332958
[TBL] [Abstract][Full Text] [Related]
17. Decreased levels of internalized thyrotropin-releasing hormone receptors after uncoupling from guanine nucleotide-binding protein and phospholipase-C.
Nussenzveig DR; Heinflink M; Gershengorn MC
Mol Endocrinol; 1993 Sep; 7(9):1105-11. PubMed ID: 8247012
[TBL] [Abstract][Full Text] [Related]
18. Synthesis and biology of ring-modified l-Histidine containing thyrotropin-releasing hormone (TRH) analogues.
Meena CL; Thakur A; Nandekar PP; Sharma SS; Sangamwar AT; Jain R
Eur J Med Chem; 2016 Mar; 111():72-83. PubMed ID: 26854379
[TBL] [Abstract][Full Text] [Related]
19. Thyrotropin-releasing hormone receptors -- similarities and differences.
Sun Y; Lu X; Gershengorn MC
J Mol Endocrinol; 2003 Apr; 30(2):87-97. PubMed ID: 12683933
[TBL] [Abstract][Full Text] [Related]
20. First-in-class thyrotropin-releasing hormone (TRH)-based compound binds to a pharmacologically distinct TRH receptor subtype in human brain and is effective in neurodegenerative models.
Kelly JA; Boyle NT; Cole N; Slator GR; Colivicchi MA; Stefanini C; Gobbo OL; Scalabrino GA; Ryan SM; Elamin M; Walsh C; Vajda A; Goggin MM; Campbell M; Mash DC; O'Mara SM; Brayden DJ; Callanan JJ; Tipton KF; Della Corte L; Hunter J; O'Boyle KM; Williams CH; Hardiman O
Neuropharmacology; 2015 Feb; 89():193-203. PubMed ID: 25281210
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]