122 related articles for article (PubMed ID: 8095956)
1. Optimal humanization of 1B4, an anti-CD18 murine monoclonal antibody, is achieved by correct choice of human V-region framework sequences.
Singer II; Kawka DW; DeMartino JA; Daugherty BL; Elliston KO; Alves K; Bush BL; Cameron PM; Cuca GC; Davies P
J Immunol; 1993 Apr; 150(7):2844-57. PubMed ID: 8095956
[TBL] [Abstract][Full Text] [Related]
2. SDR grafting of a murine antibody using multiple human germline templates to minimize its immunogenicity.
Gonzales NR; Padlan EA; De Pascalis R; Schuck P; Schlom J; Kashmiri SV
Mol Immunol; 2004 Jul; 41(9):863-72. PubMed ID: 15261458
[TBL] [Abstract][Full Text] [Related]
3. Humanization of anti-human insulin receptor antibody for drug targeting across the human blood-brain barrier.
Boado RJ; Zhang Y; Zhang Y; Pardridge WM
Biotechnol Bioeng; 2007 Feb; 96(2):381-91. PubMed ID: 16937408
[TBL] [Abstract][Full Text] [Related]
4. Humanization by variable domain resurfacing and grafting on a human IgG4, using a new approach for determination of non-human like surface accessible framework residues based on homology modelling of variable domains.
Staelens S; Desmet J; Ngo TH; Vauterin S; Pareyn I; Barbeaux P; Van Rompaey I; Stassen JM; Deckmyn H; Vanhoorelbeke K
Mol Immunol; 2006 Mar; 43(8):1243-57. PubMed ID: 16118019
[TBL] [Abstract][Full Text] [Related]
5. Humanization of an anti-lymphocyte function-associated antigen (LFA)-1 monoclonal antibody and reengineering of the humanized antibody for binding to rhesus LFA-1.
Werther WA; Gonzalez TN; O'Connor SJ; McCabe S; Chan B; Hotaling T; Champe M; Fox JA; Jardieu PM; Berman PW; Presta LG
J Immunol; 1996 Dec; 157(11):4986-95. PubMed ID: 8943405
[TBL] [Abstract][Full Text] [Related]
6. Construction and characterization of a humanized anti-gamma-Ig receptor type I (Fc gamma RI) monoclonal antibody.
Graziano RF; Tempest PR; White P; Keler T; Deo Y; Ghebremariam H; Coleman K; Pfefferkorn LC; Fanger MW; Guyre PM
J Immunol; 1995 Nov; 155(10):4996-5002. PubMed ID: 7594506
[TBL] [Abstract][Full Text] [Related]
7. Humanization and pharmacokinetics of a monoclonal antibody with specificity for both E- and P-selectin.
He XY; Xu Z; Melrose J; Mullowney A; Vasquez M; Queen C; Vexler V; Klingbeil C; Co MS; Berg EL
J Immunol; 1998 Jan; 160(2):1029-35. PubMed ID: 9551944
[TBL] [Abstract][Full Text] [Related]
8. Guided selection of a pan carcinoma specific antibody reveals similar binding characteristics yet structural divergence between the original murine antibody and its human equivalent.
Beiboer SH; Reurs A; Roovers RC; Arends JW; Whitelegg NR; Rees AR; Hoogenboom HR
J Mol Biol; 2000 Feb; 296(3):833-49. PubMed ID: 10677285
[TBL] [Abstract][Full Text] [Related]
9. Humanization of an anti-human IL-6 mouse monoclonal antibody glycosylated in its heavy chain variable region.
Sato K; Ohtomo T; Hirata Y; Saito H; Matsuura T; Akimoto T; Akamatsu K; Koishihara Y; Ohsugi Y; Tsuchiya M
Hum Antibodies Hybridomas; 1996; 7(4):175-83. PubMed ID: 9140729
[TBL] [Abstract][Full Text] [Related]
10. Humanization of a mouse antibody against human alpha-4 integrin: a potential therapeutic for the treatment of multiple sclerosis.
Léger OJ; Yednock TA; Tanner L; Horner HC; Hines DK; Keen S; Saldanha J; Jones ST; Fritz LC; Bendig MM
Hum Antibodies; 1997; 8(1):3-16. PubMed ID: 9265500
[TBL] [Abstract][Full Text] [Related]
11. Generation and characterization of a recombinant/chimeric B72.3 (human gamma 1).
Hutzell P; Kashmiri S; Colcher D; Primus FJ; Hand PH; Roselli M; Finch M; Yarranton G; Bodmer M; Whittle N
Cancer Res; 1991 Jan; 51(1):181-9. PubMed ID: 1988082
[TBL] [Abstract][Full Text] [Related]
12. Humanization of a highly stable single-chain antibody by structure-based antigen-binding site grafting.
Villani ME; Morea V; Consalvi V; Chiaraluce R; Desiderio A; Benvenuto E; Donini M
Mol Immunol; 2008 May; 45(9):2474-85. PubMed ID: 18313757
[TBL] [Abstract][Full Text] [Related]
13. X-ray structures of fragments from binding and nonbinding versions of a humanized anti-CD18 antibody: structural indications of the key role of VH residues 59 to 65.
Eigenbrot C; Gonzalez T; Mayeda J; Carter P; Werther W; Hotaling T; Fox J; Kessler J
Proteins; 1994 Jan; 18(1):49-62. PubMed ID: 7908437
[TBL] [Abstract][Full Text] [Related]
14. SDR grafting--a new approach to antibody humanization.
Kashmiri SV; De Pascalis R; Gonzales NR; Schlom J
Methods; 2005 May; 36(1):25-34. PubMed ID: 15848072
[TBL] [Abstract][Full Text] [Related]
15. Humanization of a murine monoclonal antibody by simultaneous optimization of framework and CDR residues.
Wu H; Nie Y; Huse WD; Watkins JD
J Mol Biol; 1999 Nov; 294(1):151-62. PubMed ID: 10556035
[TBL] [Abstract][Full Text] [Related]
16. Engineered anti-CD38 monoclonal antibodies for immunotherapy of multiple myeloma.
Ellis JH; Barber KA; Tutt A; Hale C; Lewis AP; Glennie MJ; Stevenson GT; Crowe JS
J Immunol; 1995 Jul; 155(2):925-37. PubMed ID: 7608568
[TBL] [Abstract][Full Text] [Related]
17. A humanized CD18 antibody can block function without cell destruction.
Sims MJ; Hassal DG; Brett S; Rowan W; Lockyer MJ; Angel A; Lewis AP; Hale G; Waldmann H; Crowe JS
J Immunol; 1993 Aug; 151(4):2296-308. PubMed ID: 7688398
[TBL] [Abstract][Full Text] [Related]
18. Comparison of the three-dimensional structures of a humanized and a chimeric Fab of an anti-gamma-interferon antibody.
Fan ZC; Shan L; Goldsteen BZ; Guddat LW; Thakur A; Landolfi NF; Co MS; Vasquez M; Queen C; Ramsland PA; Edmundson AB
J Mol Recognit; 1999; 12(1):19-32. PubMed ID: 10398393
[TBL] [Abstract][Full Text] [Related]
19. Humanization of Immu31, an alpha-fetoprotein-specific antibody.
Qu Z; Losman MJ; Eliassen KC; Hansen HJ; Goldenberg DM; Leung SO
Clin Cancer Res; 1999 Oct; 5(10 Suppl):3095s-3100s. PubMed ID: 10541349
[TBL] [Abstract][Full Text] [Related]
20. The critical role of arginine residues in the binding of human monoclonal antibodies to cardiolipin.
Giles I; Lambrianides N; Latchman D; Chen P; Chukwuocha R; Isenberg D; Rahman A
Arthritis Res Ther; 2005; 7(1):R47-56. PubMed ID: 15642142
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
