BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 8100510)

  • 1. Metabolic N-demethylation of 1,3-bis[[1-cycloheptyl-3-(p- dimethylaminophenyl)ureido]methyl]benzene dihydrochloride, a novel acyl-coenzyme A:cholesterol acyltransferase inhibitor.
    Uchida T; Usui T; Teramura T; Watanabe T; Higuchi S
    Drug Metab Dispos; 1993; 21(3):524-9. PubMed ID: 8100510
    [TBL] [Abstract][Full Text] [Related]  

  • 2. In-vitro metabolism of YM17E, an inhibitor of acyl coenzyme A:cholesterol acyltransferase, by liver microsomes in man.
    Uchida T; Watanabe T; Van Hoogdalem EJ; Higuchi S
    J Pharm Pharmacol; 1996 Oct; 48(10):1049-56. PubMed ID: 8953507
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Disposition and metabolism of a novel diurea inhibitor of acyl CoA: cholesterol acyltransferase (YM17E) in the rat and dog.
    Uchida T; Nakamura E; Usui T; Imasaki H; Kawakami R; Watanabe T; Higuchi S
    Xenobiotica; 1994 Dec; 24(12):1223-36. PubMed ID: 7771109
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The metabolism of 1-phenyl-2-(N-methyl-N-furfurylamino)propane (furfenorex) in the rat in vivo and in vitro.
    Inoue T; Yasuda T; Suzuki S; Kishi T; Niwaguchi T
    Xenobiotica; 1986 Feb; 16(2):109-21. PubMed ID: 3962333
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Biotransformation of 6-methoxy-3-(3',4',5'-trimethoxy-benzoyl)-1H-indole (BPR0L075), a novel antimicrotubule agent, by mouse, rat, dog, and human liver microsomes.
    Yao HT; Wu YS; Chang YW; Hsieh HP; Chen WC; Lan SJ; Chen CT; Chao YS; Chang L; Sun HY; Yeh TK
    Drug Metab Dispos; 2007 Jul; 35(7):1042-9. PubMed ID: 17403915
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Metabolism of a new P-glycoprotein inhibitor HM-30181 in rats using liquid chromatography/electrospray mass spectrometry.
    Paek IB; Ji HY; Kim MS; Lee G; Lee HS
    Rapid Commun Mass Spectrom; 2006; 20(9):1457-62. PubMed ID: 16586459
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Biotransformation of lovastatin. II. In vitro metabolism by rat and mouse liver microsomes and involvement of cytochrome P-450 in dehydrogenation of lovastatin.
    Vyas KP; Kari PH; Prakash SR; Duggan DE
    Drug Metab Dispos; 1990; 18(2):218-22. PubMed ID: 1971576
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Pharmacological properties of YM17E, an acyl-CoA:cholesterol acyltransferase inhibitor, and diarrheal effect in beagle dogs.
    Kashiwa M; Masuyama Y; Miyauchi H; Uchida T; Naganuma S; Kakuta H; Terada M; Kiriyama T; Matsuda K; Ito N; Iizumi Y; Takenaka T
    Jpn J Pharmacol; 1997 Jan; 73(1):41-50. PubMed ID: 9032133
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism of the antimammary cancer antiestrogenic agent tamoxifen. I. Cytochrome P-450-catalyzed N-demethylation and 4-hydroxylation.
    Mani C; Gelboin HV; Park SS; Pearce R; Parkinson A; Kupfer D
    Drug Metab Dispos; 1993; 21(4):645-56. PubMed ID: 8104124
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Metabolism of olaquindox in rat liver microsomes: structural elucidation of metabolites by high-performance liquid chromatography combined with ion trap/time-of-flight mass spectrometry.
    Liu Z; Huang L; Dai M; Chen D; Wang Y; Tao Y; Yuan Z
    Rapid Commun Mass Spectrom; 2008 Apr; 22(7):1009-16. PubMed ID: 18320546
    [TBL] [Abstract][Full Text] [Related]  

  • 11. In vitro metabolism study of combretastatin A-4 in rat and human liver microsomes.
    Aprile S; Del Grosso E; Tron GC; Grosa G
    Drug Metab Dispos; 2007 Dec; 35(12):2252-61. PubMed ID: 17890446
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro identification of metabolites of verapamil in rat liver microsomes.
    Sun L; Zhang SQ; Zhong DF
    Acta Pharmacol Sin; 2004 Jan; 25(1):121-8. PubMed ID: 14704133
    [TBL] [Abstract][Full Text] [Related]  

  • 13. In vitro metabolism of the antianxiety drug buspirone as a predictor of its metabolism in vivo.
    Jajoo HK; Blair IA; Klunk LJ; Mayol RF
    Xenobiotica; 1990 Aug; 20(8):779-86. PubMed ID: 2219961
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Metabolism of cinobufagin in rat liver microsomes. Identification of epimerized and deacetylated metabolites by liquid chromatography/mass spectrometry.
    Zhang LS; Yoshida T; Aoki K; Kuroiwa Y
    Drug Metab Dispos; 1991; 19(5):917-9. PubMed ID: 1686236
    [TBL] [Abstract][Full Text] [Related]  

  • 15. In vitro metabolism of nefiracetam by liver microsomes from rats, dogs and monkeys.
    Fujimaki Y; Sudo K; Hakusui H
    Arzneimittelforschung; 1995 Jul; 45(7):748-52. PubMed ID: 8573215
    [TBL] [Abstract][Full Text] [Related]  

  • 16. CYP2C8- and CYP3A-mediated C-demethylation of (3-{[(4-tert-butylbenzyl)-(pyridine-3-sulfonyl)-amino]-methyl}-phenoxy)-acetic acid (CP-533,536), an EP2 receptor-selective prostaglandin E2 agonist: characterization of metabolites by high-resolution liquid chromatography-tandem mass spectrometry and liquid chromatography/mass spectrometry-nuclear magnetic resonance.
    Prakash C; Wang W; O'Connell T; Johnson KA
    Drug Metab Dispos; 2008 Oct; 36(10):2093-103. PubMed ID: 18653741
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Stereoselective metabolism of cibenzoline, an antiarrhythmic drug, by human and rat liver microsomes: possible involvement of CYP2D and CYP3A.
    Niwa T; Shiraga T; Mitani Y; Terakawa M; Tokuma Y; Kagayama A
    Drug Metab Dispos; 2000 Sep; 28(9):1128-34. PubMed ID: 10950860
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Metabolism of bambuterol in rat liver microsomes: identification of hydroxylated and demethylated products by liquid chromatography mass spectrometry.
    Lindberg C; Roos C; Tunek A; Svensson LA
    Drug Metab Dispos; 1989; 17(3):311-22. PubMed ID: 2568914
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Metabolism of cyadox in rat, chicken and pig liver microsomes and identification of metabolites by accurate mass measurements using electrospray ionization hybrid ion trap/time-of-flight mass spectrometry.
    Liu Z; Huang L; Dai M; Chen D; Tao Y; Wang Y; Yuan Z
    Rapid Commun Mass Spectrom; 2009 Jul; 23(13):2026-34. PubMed ID: 19504544
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Simultaneous determination of a new inhibitor of acyl CoA:cholesterol acyltransferase, YM17E, and five metabolites using high-performance liquid chromatography with electrochemical detection.
    Uchida T; Usui T; Watanabe T; Higuchi S
    J Chromatogr; 1993 Mar; 613(1):179-83. PubMed ID: 8458898
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.