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2. Analysis of protein-protein interactions involved in the activation of the Shc/Grb-2 pathway by the ErbB-2 kinase. Ricci A; Lanfrancone L; Chiari R; Belardo G; Pertica C; Natali PG; Pelicci PG; Segatto O Oncogene; 1995 Oct; 11(8):1519-29. PubMed ID: 7478576 [TBL] [Abstract][Full Text] [Related]
3. A conserved amino-terminal Shc domain binds to phosphotyrosine motifs in activated receptors and phosphopeptides. van der Geer P; Wiley S; Lai VK; Olivier JP; Gish GD; Stephens R; Kaplan D; Shoelson S; Pawson T Curr Biol; 1995 Apr; 5(4):404-12. PubMed ID: 7542991 [TBL] [Abstract][Full Text] [Related]
4. Opposite effects of the p52shc/p46shc and p66shc splicing isoforms on the EGF receptor-MAP kinase-fos signalling pathway. Migliaccio E; Mele S; Salcini AE; Pelicci G; Lai KM; Superti-Furga G; Pawson T; Di Fiore PP; Lanfrancone L; Pelicci PG EMBO J; 1997 Feb; 16(4):706-16. PubMed ID: 9049300 [TBL] [Abstract][Full Text] [Related]
5. Formation of Shc-Grb2 complexes is necessary to induce neoplastic transformation by overexpression of Shc proteins. Salcini AE; McGlade J; Pelicci G; Nicoletti I; Pawson T; Pelicci PG Oncogene; 1994 Oct; 9(10):2827-36. PubMed ID: 8084588 [TBL] [Abstract][Full Text] [Related]
6. Gads is a novel SH2 and SH3 domain-containing adaptor protein that binds to tyrosine-phosphorylated Shc. Liu SK; McGlade CJ Oncogene; 1998 Dec; 17(24):3073-82. PubMed ID: 9872323 [TBL] [Abstract][Full Text] [Related]
7. The src homology 2 and phosphotyrosine binding domains of the ShcC adaptor protein function as inhibitors of mitogenic signaling by the epidermal growth factor receptor. O'Bryan JP; Lambert QT; Der CJ J Biol Chem; 1998 Aug; 273(32):20431-7. PubMed ID: 9685397 [TBL] [Abstract][Full Text] [Related]
8. The Shc adaptor protein is highly phosphorylated at conserved, twin tyrosine residues (Y239/240) that mediate protein-protein interactions. van der Geer P; Wiley S; Gish GD; Pawson T Curr Biol; 1996 Nov; 6(11):1435-44. PubMed ID: 8939605 [TBL] [Abstract][Full Text] [Related]
9. Direct interaction between Shc and the platelet-derived growth factor beta-receptor. Yokote K; Mori S; Hansen K; McGlade J; Pawson T; Heldin CH; Claesson-Welsh L J Biol Chem; 1994 May; 269(21):15337-43. PubMed ID: 8195171 [TBL] [Abstract][Full Text] [Related]
10. Involvement of ErbB2 in the signaling pathway leading to cell cycle progression from a truncated epidermal growth factor receptor lacking the C-terminal autophosphorylation sites. Sasaoka T; Langlois WJ; Bai F; Rose DW; Leitner JW; Decker SJ; Saltiel A; Gill GN; Kobayashi M; Draznin B; Olefsky JM J Biol Chem; 1996 Apr; 271(14):8338-44. PubMed ID: 8626530 [TBL] [Abstract][Full Text] [Related]
11. Evidence for the direct interaction of the insulin-like growth factor I receptor with IRS-1, Shc, and Grb10. Dey BR; Frick K; Lopaczynski W; Nissley SP; Furlanetto RW Mol Endocrinol; 1996 Jun; 10(6):631-41. PubMed ID: 8776723 [TBL] [Abstract][Full Text] [Related]
12. B cell antigen receptor cross-linking induces tyrosine phosphorylation and membrane translocation of a multimeric Shc complex that is augmented by CD19 co-ligation. Lankester AC; van Schijndel GM; Rood PM; Verhoeven AJ; van Lier RA Eur J Immunol; 1994 Nov; 24(11):2818-25. PubMed ID: 7525306 [TBL] [Abstract][Full Text] [Related]
13. Transformation by polyoma virus middle T-antigen involves the binding and tyrosine phosphorylation of Shc. Dilworth SM; Brewster CE; Jones MD; Lanfrancone L; Pelicci G; Pelicci PG Nature; 1994 Jan; 367(6458):87-90. PubMed ID: 7509037 [TBL] [Abstract][Full Text] [Related]
14. Grb2 and Shc adapter proteins play distinct roles in Neu (ErbB-2)-induced mammary tumorigenesis: implications for human breast cancer. Dankort D; Maslikowski B; Warner N; Kanno N; Kim H; Wang Z; Moran MF; Oshima RG; Cardiff RD; Muller WJ Mol Cell Biol; 2001 Mar; 21(5):1540-51. PubMed ID: 11238891 [TBL] [Abstract][Full Text] [Related]
15. The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing. Waterman H; Alroy I; Strano S; Seger R; Yarden Y EMBO J; 1999 Jun; 18(12):3348-58. PubMed ID: 10369675 [TBL] [Abstract][Full Text] [Related]
16. A Drosophila shc gene product is implicated in signaling by the DER receptor tyrosine kinase. Lai KM; Olivier JP; Gish GD; Henkemeyer M; McGlade J; Pawson T Mol Cell Biol; 1995 Sep; 15(9):4810-8. PubMed ID: 7651398 [TBL] [Abstract][Full Text] [Related]
17. Binding of Shc to the NPXY motif is mediated by its N-terminal domain. Prigent SA; Pillay TS; Ravichandran KS; Gullick WJ J Biol Chem; 1995 Sep; 270(38):22097-100. PubMed ID: 7673183 [TBL] [Abstract][Full Text] [Related]
18. A region in Shc distinct from the SH2 domain can bind tyrosine-phosphorylated growth factor receptors. Blaikie P; Immanuel D; Wu J; Li N; Yajnik V; Margolis B J Biol Chem; 1994 Dec; 269(51):32031-4. PubMed ID: 7798194 [TBL] [Abstract][Full Text] [Related]
19. p66Shc isoform down-regulated and not required for HER-2/neu signaling pathway in human breast cancer cell lines with HER-2/neu overexpression. Xie Y; Hung MC Biochem Biophys Res Commun; 1996 Apr; 221(1):140-5. PubMed ID: 8660324 [TBL] [Abstract][Full Text] [Related]
20. Association of the Shc and Grb2/Sem5 SH2-containing proteins is implicated in activation of the Ras pathway by tyrosine kinases. Rozakis-Adcock M; McGlade J; Mbamalu G; Pelicci G; Daly R; Li W; Batzer A; Thomas S; Brugge J; Pelicci PG; Schlessinger J; Pawson T Nature; 1992 Dec; 360(6405):689-92. PubMed ID: 1465135 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]