These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
128 related articles for article (PubMed ID: 8102912)
1. Differential reversal of lipophilic antifolate resistance in mammalian cells with modulators of the multidrug resistance phenotype. Assaraf YG; Borgnia MJ Anticancer Drugs; 1993 Jun; 4(3):395-406. PubMed ID: 8102912 [TBL] [Abstract][Full Text] [Related]
2. Sequential amplification of dihydrofolate reductase and multidrug resistance genes in Chinese hamster ovary cells selected for stepwise resistance to the lipid-soluble antifolate trimetrexate. Assaraf YG; Molina A; Schimke RT J Biol Chem; 1989 Nov; 264(31):18326-34. PubMed ID: 2572592 [TBL] [Abstract][Full Text] [Related]
3. Characterization of a lipophilic antifolate resistance provoked by treatment of mammalian cells with the antiparasitic agent pyrimethamine. Assaraf YG; Slotky JI J Biol Chem; 1993 Feb; 268(6):4556-66. PubMed ID: 8440739 [TBL] [Abstract][Full Text] [Related]
4. A phenotype conferring selective resistance to lipophilic antifolates in Chinese hamster ovary cells. Sharma RC; Assaraf YG; Schimke RT Cancer Res; 1991 Jun; 51(11):2949-59. PubMed ID: 1674447 [TBL] [Abstract][Full Text] [Related]
5. Cross-resistance to the lipid-soluble antifolate trimetrexate in human carcinoma cells with the multidrug-resistant phenotype. Assaraf YG; Molina A; Schimke RT J Natl Cancer Inst; 1989 Feb; 81(4):290-4. PubMed ID: 2521520 [TBL] [Abstract][Full Text] [Related]
6. Expression of dihydrofolate reductase and multidrug resistance genes in trimetrexate-resistant human leukemia cell lines. Li XK; Kobayashi H; Holland JF; Ohnuma T Leuk Res; 1993 Jun; 17(6):483-90. PubMed ID: 8099375 [TBL] [Abstract][Full Text] [Related]
7. Chemical synthesis and biological properties of novel fluorescent antifolates in Pgp- and MRP-overexpressing tumour cell lines. Robson C; Wright KA; Twentyman PR; Lambert PA; Griffin RJ Biochem Pharmacol; 1998 Oct; 56(7):807-16. PubMed ID: 9774142 [TBL] [Abstract][Full Text] [Related]
8. Probing the interaction of the multidrug-resistance phenotype with the polypeptide ionophore gramicidin D via functional channel formation. Assaraf YG; Borgnia MJ Eur J Biochem; 1994 Jun; 222(3):813-24. PubMed ID: 7517866 [TBL] [Abstract][Full Text] [Related]
9. Mutations leading to antifolate resistance in Chinese hamster ovary cells after exposure to the alkylating agent ethylmethanesulfonate. Fanin R; Banerjee D; Volkenandt M; Waltham M; Li WW; Dicker AP; Schweitzer BI; Bertino JR Mol Pharmacol; 1993 Jul; 44(1):13-21. PubMed ID: 8341268 [TBL] [Abstract][Full Text] [Related]
10. Severe folate restriction results in depletion of and alteration in the composition of the intracellular folate pool, moderate sensitization to methotrexate and trimetrexate, upregulation of endogenous DHFR activity, and overexpression of metallothionein II and folate receptor alpha that, upon folate repletion, confer drug resistance to CHL cells. Zhu WY; Bunni M; Priest DG; DiCapua JL; Dressler JM; Chen Z; Melera PW J Exp Ther Oncol; 2002; 2(5):264-77. PubMed ID: 12416030 [TBL] [Abstract][Full Text] [Related]
14. Interaction of multidrug-resistant Chinese hamster ovary cells with the peptide ionophore gramicidin D. Loe DW; Sharom FJ Biochim Biophys Acta; 1994 Feb; 1190(1):72-84. PubMed ID: 7509193 [TBL] [Abstract][Full Text] [Related]
15. Microsatellite instability and clonal heterogeneity of MDR1 messenger RNA expression in trimetrexate-resistant human leukemia MOLT-3 cells developed in thymidine. Miyachi H; Ma L; Takemura Y; Kobayashi H; Hirahara I; Sonehara H; Ando Y Int J Cancer; 1999 Jul; 82(1):63-9. PubMed ID: 10360822 [TBL] [Abstract][Full Text] [Related]
16. Multidrug resistance in a human leukemic cell line selected for resistance to trimetrexate. Arkin H; Ohnuma T; Kamen BA; Holland JF; Vallabhajosula S Cancer Res; 1989 Dec; 49(23):6556-61. PubMed ID: 2573416 [TBL] [Abstract][Full Text] [Related]
17. A gene transfer strategy for making bone marrow cells resistant to trimetrexate. Spencer HT; Sleep SE; Rehg JE; Blakley RL; Sorrentino BP Blood; 1996 Mar; 87(6):2579-87. PubMed ID: 8630426 [TBL] [Abstract][Full Text] [Related]
18. Cells exposed to antifolates show increased cellular levels of proteins fused to dihydrofolate reductase: a method to modulate gene expression. Mayer-Kuckuk P; Banerjee D; Malhotra S; Doubrovin M; Iwamoto M; Akhurst T; Balatoni J; Bornmann W; Finn R; Larson S; Fong Y; Gelovani Tjuvajev J; Blasberg R; Bertino JR Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3400-5. PubMed ID: 11891321 [TBL] [Abstract][Full Text] [Related]
19. The inability of the mouse mdr2 gene to confer multidrug resistance is linked to reduced drug binding to the protein. Buschman E; Gros P Cancer Res; 1994 Sep; 54(18):4892-8. PubMed ID: 7915194 [TBL] [Abstract][Full Text] [Related]
20. Comparison of the protection of cells from antifolates by transduced human dihydrofolate reductase mutants. Patel M; Sleep SE; Lewis WS; Spencer HT; Mareya SM; Sorrentino BP; Blakley RL Hum Gene Ther; 1997 Nov; 8(17):2069-77. PubMed ID: 9414255 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]