160 related articles for article (PubMed ID: 8105891)
1. Modification of the head-group selectivity of porcine pancreatic phospholipase A2 by protein engineering.
Bhat MK; Pickersgill RW; Perry BN; Brown RA; Jones ST; Mueller-Harvey I; Sumner IG; Goodenough PW
Biochemistry; 1993 Nov; 32(45):12203-8. PubMed ID: 8105891
[TBL] [Abstract][Full Text] [Related]
2. Roles of surface hydrophobic residues in the interfacial catalysis of bovine pancreatic phospholipase A2.
Lee BI; Yoon ET; Cho W
Biochemistry; 1996 Apr; 35(13):4231-40. PubMed ID: 8672459
[TBL] [Abstract][Full Text] [Related]
3. Purification and characterization of a mutant human platelet phospholipase A2 expressed in Escherichia coli. Cleavage of a fusion protein with cyanogen bromide.
Franken PA; Van den Berg L; Huang J; Gunyuzlu P; Lugtigheid RB; Verheij HM; De Haas GH
Eur J Biochem; 1992 Jan; 203(1-2):89-98. PubMed ID: 1730245
[TBL] [Abstract][Full Text] [Related]
4. Phospholipase A2 engineering. X-ray structural and functional evidence for the interaction of lysine-56 with substrates.
Noel JP; Bingman CA; Deng TL; Dupureur CM; Hamilton KJ; Jiang RT; Kwak JG; Sekharudu C; Sundaralingam M; Tsai MD
Biochemistry; 1991 Dec; 30(51):11801-11. PubMed ID: 1751497
[TBL] [Abstract][Full Text] [Related]
5. Phospholipase A2 engineering. Deletion of the C-terminus segment changes substrate specificity and uncouples calcium and substrate binding at the zwitterionic interface.
Huang B; Yu BZ; Rogers J; Byeon IJ; Sekar K; Chen X; Sundaralingam M; Tsai MD; Jain MK
Biochemistry; 1996 Sep; 35(37):12164-74. PubMed ID: 8810924
[TBL] [Abstract][Full Text] [Related]
6. An extended binding pocket determines the polar head group specificity of porcine pancreatic phospholipase A2.
Beiboer SH; Franken PA; Cox RC; Verheij HM
Eur J Biochem; 1995 Aug; 231(3):747-53. PubMed ID: 7649176
[TBL] [Abstract][Full Text] [Related]
7. Incorporation of an unnatural amino acid in the active site of porcine pancreatic phospholipase A2. Substitution of histidine by 1,2,4-triazole-3-alanine yields an enzyme with high activity at acidic pH.
Beiboer SH; van den Berg B; Dekker N; Cox RC; Verheij HM
Protein Eng; 1996 Apr; 9(4):345-52. PubMed ID: 8738210
[TBL] [Abstract][Full Text] [Related]
8. Bacterial expression and characterization of human pancreatic phospholipase A2.
Han SK; Lee BI; Cho W
Biochim Biophys Acta; 1997 Jun; 1346(2):185-92. PubMed ID: 9219901
[TBL] [Abstract][Full Text] [Related]
9. Influence of size and polarity of residue 31 in porcine pancreatic phospholipase A2 on catalytic properties.
Kuipers OP; Kerver J; van Meersbergen J; Vis R; Dijkman R; Verheij HM; de Haas GH
Protein Eng; 1990 Jul; 3(7):599-603. PubMed ID: 2217133
[TBL] [Abstract][Full Text] [Related]
10. Interfacial catalysis by phospholipase A2: substrate specificity in vesicles.
Ghomashchi F; Yu BZ; Berg O; Jain MK; Gelb MH
Biochemistry; 1991 Jul; 30(29):7318-29. PubMed ID: 1854740
[TBL] [Abstract][Full Text] [Related]
11. Activities of native and tyrosine-69 mutant phospholipases A2 on phospholipid analogues. A reevaluation of the minimal substrate requirements.
Kuipers OP; Dekker N; Verheij HM; de Haas GH
Biochemistry; 1990 Jun; 29(25):6094-102. PubMed ID: 2116905
[TBL] [Abstract][Full Text] [Related]
12. Competitive inhibition of lipolytic enzymes. VII. The interaction of pancreatic phospholipase A2 with micellar lipid/water interfaces of competitive inhibitors.
Deveer AM; Franken PA; Dijkman R; Meeldijk J; Egmond MR; Verheij HM; Verger R; de Haas GH
Biochim Biophys Acta; 1992 Apr; 1125(1):73-81. PubMed ID: 1567910
[TBL] [Abstract][Full Text] [Related]
13. Introduction of a C-terminal aromatic sequence from snake venom phospholipases A2 into the porcine pancreatic isozyme dramatically changes the interfacial kinetics.
Janssen MJ; Burghout PJ; Verheij HM; Slotboom AJ; Egmond MR
Eur J Biochem; 1999 Aug; 263(3):782-8. PubMed ID: 10469142
[TBL] [Abstract][Full Text] [Related]
14. Thermodynamic and kinetic basis of interfacial activation: resolution of binding and allosteric effects on pancreatic phospholipase A2 at zwitterionic interfaces.
Berg OG; Rogers J; Yu BZ; Yao J; Romsted LS; Jain MK
Biochemistry; 1997 Nov; 36(47):14512-30. PubMed ID: 9398170
[TBL] [Abstract][Full Text] [Related]
15. Heparin prevents the binding of phospholipase A2 to phospholipid micelles: importance of the amino-terminus.
Diccianni MB; Lilly-Stauderman M; McLean LR; Balasubramaniam A; Harmony JA
Biochemistry; 1991 Sep; 30(37):9090-7. PubMed ID: 1892820
[TBL] [Abstract][Full Text] [Related]
16. Arginine 53 is involved in head-group specificity of the active site of porcine pancreatic phospholipase A2.
Lugtigheid RB; Otten-Kuipers MA; Verheij HM; De Haas GH
Eur J Biochem; 1993 Apr; 213(1):517-22. PubMed ID: 8477724
[TBL] [Abstract][Full Text] [Related]
17. Phospholipase A2 engineering. Probing the structural and functional roles of N-terminal residues with site-directed mutagenesis, X-ray, and NMR.
Liu X; Zhu H; Huang B; Rogers J; Yu BZ; Kumar A; Jain MK; Sundaralingam M; Tsai MD
Biochemistry; 1995 Jun; 34(22):7322-34. PubMed ID: 7779775
[TBL] [Abstract][Full Text] [Related]
18. Evidence for the involvement of tyrosine-69 in the control of stereospecificity of porcine pancreatic phospholipase A2.
Kuipers OP; Dijkman R; Pals CE; Verheij HM; de Haas GH
Protein Eng; 1989 Mar; 2(6):467-71. PubMed ID: 2710783
[TBL] [Abstract][Full Text] [Related]
19. Use of short-chain cyclopentano-phosphatidylcholines to probe the mode of activation of phospholipase A2 from bovine pancreas and bee venom.
Lin G; Noel J; Loffredo W; Stable HZ; Tsai MD
J Biol Chem; 1988 Sep; 263(26):13208-14. PubMed ID: 3417654
[TBL] [Abstract][Full Text] [Related]
20. Acylation of porcine pancreatic phospholipase A2 influences penetration and substrate head-group binding, depending on the position of the acylated lysine in the enzyme molecule.
Lugtigheid RB; Nicolaes GA; Veldhuizen EJ; Slotboom AJ; Verheij HM; De Haas GH
Eur J Biochem; 1993 Sep; 216(2):519-25. PubMed ID: 8375390
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]