209 related articles for article (PubMed ID: 8117658)
1. An anion binding site in human aldose reductase: mechanistic implications for the binding of citrate, cacodylate, and glucose 6-phosphate.
Harrison DH; Bohren KM; Ringe D; Petsko GA; Gabbay KH
Biochemistry; 1994 Mar; 33(8):2011-20. PubMed ID: 8117658
[TBL] [Abstract][Full Text] [Related]
2. Mechanism of human aldehyde reductase: characterization of the active site pocket.
Barski OA; Gabbay KH; Grimshaw CE; Bohren KM
Biochemistry; 1995 Sep; 34(35):11264-75. PubMed ID: 7669785
[TBL] [Abstract][Full Text] [Related]
3. Tyrosine-48 is the proton donor and histidine-110 directs substrate stereochemical selectivity in the reduction reaction of human aldose reductase: enzyme kinetics and crystal structure of the Y48H mutant enzyme.
Bohren KM; Grimshaw CE; Lai CJ; Harrison DH; Ringe D; Petsko GA; Gabbay KH
Biochemistry; 1994 Mar; 33(8):2021-32. PubMed ID: 8117659
[TBL] [Abstract][Full Text] [Related]
4. Human aldose reductase: pK of tyrosine 48 reveals the preferred ionization state for catalysis and inhibition.
Grimshaw CE; Bohren KM; Lai CJ; Gabbay KH
Biochemistry; 1995 Nov; 34(44):14374-84. PubMed ID: 7578041
[TBL] [Abstract][Full Text] [Related]
5. The crystal structure of an aldehyde reductase Y50F mutant-NADP complex and its implications for substrate binding.
Ye Q; Hyndman D; Green NC; Li L; Jia Z; Flynn TG
Chem Biol Interact; 2001 Jan; 130-132(1-3):651-8. PubMed ID: 11306083
[TBL] [Abstract][Full Text] [Related]
6. The alrestatin double-decker: binding of two inhibitor molecules to human aldose reductase reveals a new specificity determinant.
Harrison DH; Bohren KM; Petsko GA; Ringe D; Gabbay KH
Biochemistry; 1997 Dec; 36(51):16134-40. PubMed ID: 9405046
[TBL] [Abstract][Full Text] [Related]
7. Structure of porcine aldehyde reductase holoenzyme.
el-Kabbani O; Judge K; Ginell SL; Myles DA; DeLucas LJ; Flynn TG
Nat Struct Biol; 1995 Aug; 2(8):687-92. PubMed ID: 7552731
[TBL] [Abstract][Full Text] [Related]
8. Residues affecting the catalysis and inhibition of rat lens aldose reductase.
Carper DA; Hohman TC; Old SE
Biochim Biophys Acta; 1995 Jan; 1246(1):67-73. PubMed ID: 7811733
[TBL] [Abstract][Full Text] [Related]
9. Mechanism of aldose reductase inhibition: binding of NADP+/NADPH and alrestatin-like inhibitors.
Ehrig T; Bohren KM; Prendergast FG; Gabbay KH
Biochemistry; 1994 Jun; 33(23):7157-65. PubMed ID: 8003482
[TBL] [Abstract][Full Text] [Related]
10. Crystal structure of yeast xylose reductase in complex with a novel NADP-DTT adduct provides insights into substrate recognition and catalysis.
Paidimuddala B; Mohapatra SB; Gummadi SN; Manoj N
FEBS J; 2018 Dec; 285(23):4445-4464. PubMed ID: 30269423
[TBL] [Abstract][Full Text] [Related]
11. Probing flexibility and "induced-fit" phenomena in aldose reductase by comparative crystal structure analysis and molecular dynamics simulations.
Sotriffer CA; Krämer O; Klebe G
Proteins; 2004 Jul; 56(1):52-66. PubMed ID: 15162486
[TBL] [Abstract][Full Text] [Related]
12. Novel NADPH-binding domain revealed by the crystal structure of aldose reductase.
Rondeau JM; Tête-Favier F; Podjarny A; Reymann JM; Barth P; Biellmann JF; Moras D
Nature; 1992 Jan; 355(6359):469-72. PubMed ID: 1734286
[TBL] [Abstract][Full Text] [Related]
13. Aldose reductase as a target for drug design: molecular modeling calculations on the binding of acyclic sugar substrates to the enzyme.
De Winter HL; von Itzstein M
Biochemistry; 1995 Jul; 34(26):8299-308. PubMed ID: 7599122
[TBL] [Abstract][Full Text] [Related]
14. Aldose and aldehyde reductases: structure-function studies on the coenzyme and inhibitor-binding sites.
El-Kabbani O; Old SE; Ginell SL; Carper DA
Mol Vis; 1999 Sep; 5():20. PubMed ID: 10493777
[TBL] [Abstract][Full Text] [Related]
15. The structure of Apo R268A human aldose reductase: hinges and latches that control the kinetic mechanism.
Bohren KM; Brownlee JM; Milne AC; Gabbay KH; Harrison DH
Biochim Biophys Acta; 2005 May; 1748(2):201-12. PubMed ID: 15769597
[TBL] [Abstract][Full Text] [Related]
16. Crystal structure of Escherichia coli thioredoxin reductase refined at 2 A resolution. Implications for a large conformational change during catalysis.
Waksman G; Krishna TS; Williams CH; Kuriyan J
J Mol Biol; 1994 Feb; 236(3):800-16. PubMed ID: 8114095
[TBL] [Abstract][Full Text] [Related]
17. A 'specificity' pocket inferred from the crystal structures of the complexes of aldose reductase with the pharmaceutically important inhibitors tolrestat and sorbinil.
Urzhumtsev A; Tête-Favier F; Mitschler A; Barbanton J; Barth P; Urzhumtseva L; Biellmann JF; Podjarny A; Moras D
Structure; 1997 May; 5(5):601-12. PubMed ID: 9195881
[TBL] [Abstract][Full Text] [Related]
18. Hydrogen bonding interactions between aldose reductase complexed with NADP(H) and inhibitor tolrestat studied by molecular dynamics simulations and binding assay.
Lee YS; Hodoscek M; Kador PF; Sugiyama K
Chem Biol Interact; 2003 Feb; 143-144():307-16. PubMed ID: 12604217
[TBL] [Abstract][Full Text] [Related]
19. The crystal structure of the aldose reductase.NADPH binary complex.
Borhani DW; Harter TM; Petrash JM
J Biol Chem; 1992 Dec; 267(34):24841-7. PubMed ID: 1447221
[TBL] [Abstract][Full Text] [Related]
20. Inhibition of aldose reductase by (2,6-dimethylphenylsulphonyl)nitromethane: possible implications for the nature of an inhibitor binding site and a cause of biphasic kinetics.
Ward WH; Cook PN; Mirrlees DJ; Brittain DR; Preston J; Carey F; Tuffin DP; Howe R
Adv Exp Med Biol; 1993; 328():301-11. PubMed ID: 8493907
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
