303 related articles for article (PubMed ID: 8119179)
1. A novel D-phenylalanine-derivative hypoglycemic agent A-4166 increases cytosolic free Ca2+ in rat pancreatic beta-cells by stimulating Ca2+ influx.
Fujitani S; Yada T
Endocrinology; 1994 Mar; 134(3):1395-400. PubMed ID: 8119179
[TBL] [Abstract][Full Text] [Related]
2. The ability of a new hypoglycaemic agent, A-4166, compared to sulphonylureas, to increase cytosolic Ca2+ in pancreatic beta-cells under metabolic inhibition.
Fujitani S; Okazaki K; Yada T
Br J Pharmacol; 1997 Apr; 120(7):1191-8. PubMed ID: 9105692
[TBL] [Abstract][Full Text] [Related]
3. Somatostatin and insulin secretion due to common mechanisms by a new hypoglycemic agent, A-4166, in perfused rat pancreas.
Fujitani S; Ikenoue T; Akiyoshi M; Maki T; Yada T
Metabolism; 1996 Feb; 45(2):184-9. PubMed ID: 8596487
[TBL] [Abstract][Full Text] [Related]
4. Glucagon-like peptide-1-(7-36)amide and a rise in cyclic adenosine 3',5'-monophosphate increase cytosolic free Ca2+ in rat pancreatic beta-cells by enhancing Ca2+ channel activity.
Yada T; Itoh K; Nakata M
Endocrinology; 1993 Oct; 133(4):1685-92. PubMed ID: 8404610
[TBL] [Abstract][Full Text] [Related]
5. A new hypoglycemic agent, JTT-608, evokes protein kinase A-mediated Ca(2+) signaling in rat islet beta-cells: strict regulation by glucose, link to insulin release, and cooperation with glucagon-like peptide-1(7-36)amide and pituitary adenylate cyclase-activating polypeptide.
Hashiguchi S; Yada T; Arima T
J Pharmacol Exp Ther; 2001 Jan; 296(1):22-30. PubMed ID: 11123358
[TBL] [Abstract][Full Text] [Related]
6. Insulin secretion from isolated rat islets induced by the novel hypoglycemic agent A-4166, a derivative of D-phenylalanine.
Tsukuda K; Sakurada M; Niki I; Oka Y; Kikuchi M
Horm Metab Res; 1998 Jan; 30(1):42-9. PubMed ID: 9503038
[TBL] [Abstract][Full Text] [Related]
7. Glucose regulation of insulin secretion independent of the opening or closure of adenosine triphosphate-sensitive K+ channels in beta cells.
Sato Y; Anello M; Henquin JC
Endocrinology; 1999 May; 140(5):2252-7. PubMed ID: 10218978
[TBL] [Abstract][Full Text] [Related]
8. Effects of D-phenylalanine-derivative hypoglycemic agent A-4166 on pancreatic alpha- and beta-cells: comparative study with glibenclamide.
Hirose H; Maruyama H; Seto Y; Ito K; Fujita T; Dan K; Kanda N; Saruta T; Kato R
Pharmacology; 1995 Mar; 50(3):175-81. PubMed ID: 7746834
[TBL] [Abstract][Full Text] [Related]
9. A novel enhancer of insulinotrophic action by high glucose (JTT-608) stimulates insulin secretion from pancreatic beta-cells via a new cellular mechanism.
Itabashi N; Okada K; Muto S; Fujita N; Ohta T; Miyazaki Ji ; Asano Y; Saito T
J Pharmacol Exp Ther; 2001 Jun; 297(3):953-60. PubMed ID: 11356916
[TBL] [Abstract][Full Text] [Related]
10. Two distinct modes of Ca2+ signalling by ACh in rat pancreatic beta-cells: concentration, glucose dependence and Ca2+ origin.
Yada T; Hamakawa N; Yaekura K
J Physiol; 1995 Oct; 488 ( Pt 1)(Pt 1):13-24. PubMed ID: 8568649
[TBL] [Abstract][Full Text] [Related]
11. A new hypoglycemic agent, A-4166, inhibits ATP-sensitive potassium channels in rat pancreatic beta-cells.
Akiyoshi M; Kakei M; Nakazaki M; Tanaka H
Am J Physiol; 1995 Feb; 268(2 Pt 1):E185-93. PubMed ID: 7864093
[TBL] [Abstract][Full Text] [Related]
12. Metabolic, cationic and secretory response to D-glucose in depolarized and Ca(2+)-deprived rat islets exposed to diazoxide.
Lebrun P; Antoine MH; Nguyen QA; Picton S; Malaisse WJ
Cell Calcium; 2000 Apr; 27(4):213-22. PubMed ID: 10858667
[TBL] [Abstract][Full Text] [Related]
13. Sulfonylureas enhance exocytosis from pancreatic beta-cells by a mechanism that does not involve direct activation of protein kinase C.
Tian YA; Johnson G; Ashcroft SJ
Diabetes; 1998 Nov; 47(11):1722-6. PubMed ID: 9792541
[TBL] [Abstract][Full Text] [Related]
14. cAMP-signaling pathway acts in selective synergism with glucose or tolbutamide to increase cytosolic Ca2+ in rat pancreatic beta-cells.
Yaekura K; Kakei M; Yada T
Diabetes; 1996 Mar; 45(3):295-301. PubMed ID: 8593933
[TBL] [Abstract][Full Text] [Related]
15. Pancreatic beta-cell K(ATP) channel activity and membrane-binding studies with nateglinide: A comparison with sulfonylureas and repaglinide.
Hu S; Wang S; Fanelli B; Bell PA; Dunning BE; Geisse S; Schmitz R; Boettcher BR
J Pharmacol Exp Ther; 2000 May; 293(2):444-52. PubMed ID: 10773014
[TBL] [Abstract][Full Text] [Related]
16. Direct effects of diazoxide on mitochondria in pancreatic B-cells and on isolated liver mitochondria.
Grimmsmann T; Rustenbeck I
Br J Pharmacol; 1998 Mar; 123(5):781-8. PubMed ID: 9535004
[TBL] [Abstract][Full Text] [Related]
17. Hypoglycaemic and insulinotropic effects of a novel oral antidiabetic agent, (-)-N-(trans-4-isopropylcyclohexanecarbonyl)-D-phenylalanine (A-4166).
Ikenoue T; Akiyoshi M; Fujitani S; Okazaki K; Kondo N; Maki T
Br J Pharmacol; 1997 Jan; 120(1):137-45. PubMed ID: 9117089
[TBL] [Abstract][Full Text] [Related]
18. Interaction of nateglinide with K(ATP) channel in beta-cells underlies its unique insulinotropic action.
Hu S
Eur J Pharmacol; 2002 May; 442(1-2):163-71. PubMed ID: 12020694
[TBL] [Abstract][Full Text] [Related]
19. Glucose stimulates glucagon release in single rat alpha-cells by mechanisms that mirror the stimulus-secretion coupling in beta-cells.
Olsen HL; Theander S; Bokvist K; Buschard K; Wollheim CB; Gromada J
Endocrinology; 2005 Nov; 146(11):4861-70. PubMed ID: 16081632
[TBL] [Abstract][Full Text] [Related]
20. Sulfonylurea induced beta-cell apoptosis in cultured human islets.
Maedler K; Carr RD; Bosco D; Zuellig RA; Berney T; Donath MY
J Clin Endocrinol Metab; 2005 Jan; 90(1):501-6. PubMed ID: 15483097
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]