160 related articles for article (PubMed ID: 8131209)
1. Human renal cell carcinoma cells are sensitive to the cytotoxic effect of a chimeric protein composed of human interleukin-4 and Pseudomonas exotoxin.
Puri RK; Debinski W; Obiri N; Kreitman R; Pastan I
Cell Immunol; 1994 Apr; 154(1):369-79. PubMed ID: 8131209
[TBL] [Abstract][Full Text] [Related]
2. A wide range of human cancers express interleukin 4 (IL4) receptors that can be targeted with chimeric toxin composed of IL4 and Pseudomonas exotoxin.
Debinski W; Puri RK; Kreitman RJ; Pastan I
J Biol Chem; 1993 Jul; 268(19):14065-70. PubMed ID: 8314773
[TBL] [Abstract][Full Text] [Related]
3. An improved circularly permuted interleukin 4-toxin is highly cytotoxic to human renal cell carcinoma cells. Introduction of gamma c chain in RCC cells does not improve sensitivity.
Puri RK; Leland P; Obiri NI; Husain SR; Mule J; Pastan I; Kreitman RJ
Cell Immunol; 1996 Jul; 171(1):80-6. PubMed ID: 8660841
[TBL] [Abstract][Full Text] [Related]
4. A chimeric protein comprised of IL-4 and Pseudomonas exotoxin is cytotoxic for activated human lymphocytes.
Puri RK; Mehrotra PT; Leland P; Kreitman RJ; Siegel JP; Pastan I
J Immunol; 1994 Apr; 152(7):3693-700. PubMed ID: 8144944
[TBL] [Abstract][Full Text] [Related]
5. Targeting of interleukin-13 receptor on human renal cell carcinoma cells by a recombinant chimeric protein composed of interleukin-13 and a truncated form of Pseudomonas exotoxin A (PE38QQR).
Puri RK; Leland P; Obiri NI; Husain SR; Kreitman RJ; Haas GP; Pastan I; Debinski W
Blood; 1996 May; 87(10):4333-9. PubMed ID: 8639793
[TBL] [Abstract][Full Text] [Related]
6. Human neurological cancer cells express interleukin-4 (IL-4) receptors which are targets for the toxic effects of IL4-Pseudomonas exotoxin chimeric protein.
Puri RK; Leland P; Kreitman RJ; Pastan I
Int J Cancer; 1994 Aug; 58(4):574-81. PubMed ID: 8056454
[TBL] [Abstract][Full Text] [Related]
7. A novel chimeric protein composed of interleukin 13 and Pseudomonas exotoxin is highly cytotoxic to human carcinoma cells expressing receptors for interleukin 13 and interleukin 4.
Debinski W; Obiri NI; Pastan I; Puri RK
J Biol Chem; 1995 Jul; 270(28):16775-80. PubMed ID: 7622490
[TBL] [Abstract][Full Text] [Related]
8. Interleukin-4 receptors expressed on tumor cells may serve as a target for anticancer therapy using chimeric Pseudomonas exotoxin.
Debinski W; Puri RK; Pastan I
Int J Cancer; 1994 Sep; 58(5):744-8. PubMed ID: 8077061
[TBL] [Abstract][Full Text] [Related]
9. Interleukin-6 fused to a mutant form of Pseudomonas exotoxin kills malignant cells from patients with multiple myeloma.
Kreitman RJ; Siegall CB; FitzGerald DJ; Epstein J; Barlogie B; Pastan I
Blood; 1992 Apr; 79(7):1775-80. PubMed ID: 1558971
[TBL] [Abstract][Full Text] [Related]
10. Receptor for interleukin (IL) 13 does not interact with IL4 but receptor for IL4 interacts with IL13 on human glioma cells.
Debinski W; Miner R; Leland P; Obiri NI; Puri RK
J Biol Chem; 1996 Sep; 271(37):22428-33. PubMed ID: 8798406
[TBL] [Abstract][Full Text] [Related]
11. Pediatric acute myelogenous leukemia cells express IL-6 receptors and are sensitive to a recombinant IL6-Pseudomonas exotoxin.
Boayue KB; Gu L; Yeager AM; Kreitman RJ; Findley HW
Leukemia; 1998 Feb; 12(2):182-91. PubMed ID: 9519780
[TBL] [Abstract][Full Text] [Related]
12. Preclinical development of a recombinant toxin containing circularly permuted interleukin 4 and truncated Pseudomonas exotoxin for therapy of malignant astrocytoma.
Puri RK; Hoon DS; Leland P; Snoy P; Rand RW; Pastan I; Kreitman RJ
Cancer Res; 1996 Dec; 56(24):5631-7. PubMed ID: 8971168
[TBL] [Abstract][Full Text] [Related]
13. Basic fibroblast growth factor-Pseudomonas exotoxin chimeric proteins; comparison with acidic fibroblast growth factor-Pseudomonas exotoxin.
Gawlak SL; Pastan I; Siegall CB
Bioconjug Chem; 1993; 4(6):483-9. PubMed ID: 7508267
[TBL] [Abstract][Full Text] [Related]
14. Expression of high affinity interleukin-4 receptors on human renal cell carcinoma cells and inhibition of tumor cell growth in vitro by interleukin-4.
Obiri NI; Hillman GG; Haas GP; Sud S; Puri RK
J Clin Invest; 1993 Jan; 91(1):88-93. PubMed ID: 8423237
[TBL] [Abstract][Full Text] [Related]
15. Development of a recombinant interleukin-4-Pseudomonas exotoxin for therapy of glioblastoma.
Puri RK
Toxicol Pathol; 1999; 27(1):53-7. PubMed ID: 10367674
[TBL] [Abstract][Full Text] [Related]
16. Pancreatic cancer cells express interleukin-13 and -4 receptors, and their growth is inhibited by Pseudomonas exotoxin coupled to interleukin-13 and -4.
Kornmann M; Kleeff J; Debinski W; Korc M
Anticancer Res; 1999; 19(1A):125-31. PubMed ID: 10226533
[TBL] [Abstract][Full Text] [Related]
17. Human breast carcinoma cells express type II IL-4 receptors and are sensitive to antitumor activity of a chimeric IL-4-Pseudomonas exotoxin fusion protein in vitro and in vivo.
Leland P; Taguchi J; Husain SR; Kreitman RJ; Pastan I; Puri RK
Mol Med; 2000 Mar; 6(3):165-78. PubMed ID: 10965493
[TBL] [Abstract][Full Text] [Related]
18. Cytotoxic activity of a recombinant fusion protein between interleukin 4 and Pseudomonas exotoxin.
Ogata M; Chaudhary VK; FitzGerald DJ; Pastan I
Proc Natl Acad Sci U S A; 1989 Jun; 86(11):4215-9. PubMed ID: 2657746
[TBL] [Abstract][Full Text] [Related]
19. Expression of high-affinity interleukin 4 receptors on murine sarcoma cells and receptor-mediated cytotoxicity of tumor cells to chimeric protein between interleukin 4 and Pseudomonas exotoxin.
Puri RK; Ogata M; Leland P; Feldman GM; FitzGerald D; Pastan I
Cancer Res; 1991 Jun; 51(11):3011-7. PubMed ID: 2032239
[TBL] [Abstract][Full Text] [Related]
20. IL2-PE664Glu, a new chimeric protein cytotoxic to human-activated T lymphocytes.
Lorberboum-Galski H; Garsia RJ; Gately M; Brown PS; Clark RE; Waldmann TA; Chaudhary VK; FitzGerald DJ; Pastan I
J Biol Chem; 1990 Sep; 265(27):16311-7. PubMed ID: 1975810
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
