BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

143 related articles for article (PubMed ID: 8132526)

  • 21. Increased sensitivity of thymidine kinase-deficient (TK-) tumor cell lines to the cell growth inhibitory effects of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and related compounds.
    Balzarini J; De Clercq E; Verbruggen A; Crumpacker C; Ayusawa D; Seno T
    Anticancer Res; 1986; 6(5):1077-84. PubMed ID: 2432829
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Anti-herpes simplex virus and anti-human cell growth activity of E-5-propenyl-2'-deoxyuridine and the concept of selective protection in antivirus chemotherapy.
    Cheng YC; Grill S; Ruth J; Bergstrom DE
    Antimicrob Agents Chemother; 1980 Dec; 18(6):957-61. PubMed ID: 6263181
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides.
    Balzarini J; McGuigan C
    Biochim Biophys Acta; 2002 Jul; 1587(2-3):287-95. PubMed ID: 12084470
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Deoxythymidine kinase induced in the HELA TK- cells by herpes simplex virus type I and type II. Substrate specificity and kinetic behavior.
    Cheng YC
    Biochim Biophys Acta; 1976 Dec; 452(2):370-81. PubMed ID: 188465
    [TBL] [Abstract][Full Text] [Related]  

  • 25. N1-substituted thymine derivatives as mitochondrial thymidine kinase (TK-2) inhibitors.
    Hernandez AI; Familiar O; Negri A; Rodríguez-Barrios F; Gago F; Karlsson A; Camarasa MJ; Balzarini J; Pérez-Pérez MJ
    J Med Chem; 2006 Dec; 49(26):7766-73. PubMed ID: 17181158
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Kinetic studies with N2-phenylguanines and with L-thymidine indicate that herpes simplex virus type-1 thymidine kinase and thymidylate kinase share a common active site.
    Maga G; Focher F; Wright GE; Capobianco M; Garbesi A; Bendiscioli A; Spadari S
    Biochem J; 1994 Aug; 302 ( Pt 1)(Pt 1):279-82. PubMed ID: 8068016
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Non-nucleoside inhibitors of mitochondrial thymidine kinase (TK-2) differentially inhibit the closely related herpes simplex virus type 1 TK and Drosophila melanogaster multifunctional deoxynucleoside kinase.
    Balzarini J; Hernández AI; Roche P; Esnouf R; Karlsson A; Camarasa MJ; Pérez-Pérez MJ
    Mol Pharmacol; 2003 Feb; 63(2):263-70. PubMed ID: 12527796
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Antiviral activity of the 3'-amino derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine.
    De Clercq E; Descamps J; Balzarini J; Fukui T; Allaudeen HS
    Biochem J; 1983 May; 211(2):439-45. PubMed ID: 6307280
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The N-7-substituted acyclic nucleoside analog 2-amino-7-[(1,3-dihydroxy-2-propoxy)methyl]purine is a potent and selective inhibitor of herpesvirus replication.
    Neyts J; Andrei G; Snoeck R; Jähne G; Winkler I; Helsberg M; Balzarini J; De Clercq E
    Antimicrob Agents Chemother; 1994 Dec; 38(12):2710-6. PubMed ID: 7695251
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Inhibition of herpes simplex virus thymidine kinases by 2-phenylamino-6-oxopurines and related compounds: structure-activity relationships and antiherpetic activity in vivo.
    Manikowski A; Verri A; Lossani A; Gebhardt BM; Gambino J; Focher F; Spadari S; Wright GE
    J Med Chem; 2005 Jun; 48(11):3919-29. PubMed ID: 15916444
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human mitochondrial thymidine kinase is selectively inhibited by 3'-thiourea derivatives of beta-thymidine: identification of residues crucial for both inhibition and catalytic activity.
    Balzarini J; Van Daele I; Negri A; Solaroli N; Karlsson A; Liekens S; Gago F; Van Calenbergh S
    Mol Pharmacol; 2009 May; 75(5):1127-36. PubMed ID: 19233899
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Cytotoxicity and cellular uptake of pyrimidine nucleosides for imaging herpes simplex type-1 thymidine kinase (HSV-1 TK) expression in mammalian cells.
    Morin KW; Duan W; Xu L; Zhou A; Moharram S; Knaus EE; McEwan AJ; Wiebe LI
    Nucl Med Biol; 2004 Jul; 31(5):623-30. PubMed ID: 15219281
    [TBL] [Abstract][Full Text] [Related]  

  • 33. 5-alkynyl analogs of arabinouridine and 2'-deoxyuridine: cytostatic activity against herpes simplex virus and varicella-zoster thymidine kinase gene-transfected cells.
    Cristofoli WA; Wiebe LI; De Clercq E; Andrei G; Snoeck R; Balzarini J; Knaus EE
    J Med Chem; 2007 Jun; 50(12):2851-7. PubMed ID: 17518459
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Bystander effect of purine nucleoside analogues in HSV-1 tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues.
    Degrève B; De Clercq E; Balzarini J
    Gene Ther; 1999 Feb; 6(2):162-70. PubMed ID: 10435100
    [TBL] [Abstract][Full Text] [Related]  

  • 35. 5-Iodo-2'-deoxy-L-uridine and (E)-5-(2-bromovinyl)-2'-deoxy-L-uridine: selective phosphorylation by herpes simplex virus type 1 thymidine kinase, antiherpetic activity, and cytotoxicity studies.
    Spadari S; Ciarrocchi G; Focher F; Verri A; Maga G; Arcamone F; Iafrate E; Manzini S; Garbesi A; Tondelli L
    Mol Pharmacol; 1995 Jun; 47(6):1231-8. PubMed ID: 7603465
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Substrate specificity of feline and canine herpesvirus thymidine kinase.
    Solaroli N; Johansson M; Persoons L; Balzarini J; Karlsson A
    Antiviral Res; 2008 Aug; 79(2):128-32. PubMed ID: 18455811
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Establishment and use of a cell line expressing HSV-1 thymidine kinase to characterize viral thymidine kinase-dependent drug-resistance.
    Kim JH; Park JB; Bae PK; Kim HS; Kim DW; Ahn JK; Lee CK
    Antiviral Res; 2002 Jun; 54(3):163-74. PubMed ID: 12062389
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Comparison of HSV-1 thymidine kinase-dependent and -independent inhibition of replication-competent adenoviral vectors by a panel of drugs.
    Wildner O; Hoffmann D; Jogler C; Uberla K
    Cancer Gene Ther; 2003 Oct; 10(10):791-802. PubMed ID: 14502232
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Bicyclic pyrimidine nucleoside analogues (BCNAs) as highly selective and potent inhibitors of varicella-zoster virus replication.
    Balzarini J; McGuigan C
    J Antimicrob Chemother; 2002 Jul; 50(1):5-9. PubMed ID: 12096000
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Synthesis and cellular uptake of 2'-substituted analogues of (E)-5-(2-[125I]iodovinyl)-2'-deoxyuridine in tumor cells transduced with the herpes simplex type-1 thymidine kinase gene. Evaluation as probes for monitoring gene therapy.
    Morin KW; Atrazheva ED; Knaus EE; Wiebe LI
    J Med Chem; 1997 Jul; 40(14):2184-90. PubMed ID: 9216837
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 8.