These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

86 related articles for article (PubMed ID: 8142398)

  • 21. A 109-amino-acid C-terminal fragment of Alzheimer's-disease amyloid precursor protein contains a sequence, -RHDS-, that promotes cell adhesion.
    Ghiso J; Rostagno A; Gardella JE; Liem L; Gorevic PD; Frangione B
    Biochem J; 1992 Dec; 288 ( Pt 3)(Pt 3):1053-9. PubMed ID: 1281980
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Enzymatic generation of the amino terminus of the beta-amyloid peptide.
    Sahasrabudhe SR; Brown AM; Hulmes JD; Jacobsen JS; Vitek MP; Blume AJ; Sonnenberg JL
    J Biol Chem; 1993 Aug; 268(22):16699-705. PubMed ID: 8344949
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein beta-secretase.
    Sauder JM; Arthur JW; Dunbrack RL
    J Mol Biol; 2000 Jul; 300(2):241-8. PubMed ID: 10873463
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Studies on the proteolytic degradation of the beta-protein precursor by proteases purified from Alzheimer's disease brain.
    Abraham CR; Razzaboni BL; Sisodia SS; Koo EH; Price DL; Van Nostrand WE; Papastoitsis G
    Ann N Y Acad Sci; 1991; 640():161-5. PubMed ID: 1776735
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Intracellular generation of amyloid beta-protein from amyloid beta-protein precursor fragment by direct cleavage with beta- and gamma-secretase.
    Iizuka T; Shoji M; Kawarabayashi T; Sato M; Kobayashi T; Tada N; Kasai K; Matsubara E; Watanabe M; Tomidokoro Y; Hirai S
    Biochem Biophys Res Commun; 1996 Jan; 218(1):238-42. PubMed ID: 8573139
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Cross-linking of a synthetic partial-length (1-28) peptide of the Alzheimer beta/A4 amyloid protein by transglutaminase.
    Ikura K; Takahata K; Sasaki R
    FEBS Lett; 1993 Jul; 326(1-3):109-11. PubMed ID: 8100780
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Familial Alzheimer's disease mutations inhibit gamma-secretase-mediated liberation of beta-amyloid precursor protein carboxy-terminal fragment.
    Wiley JC; Hudson M; Kanning KC; Schecterson LC; Bothwell M
    J Neurochem; 2005 Sep; 94(5):1189-201. PubMed ID: 15992373
    [TBL] [Abstract][Full Text] [Related]  

  • 28. The processing of Alzheimer A4/beta-amyloid protein precursor: identification of a human brain metallopeptidase which cleaves -Lys-Leu- in a model peptide.
    McDermott JR; Gibson AM
    Biochem Biophys Res Commun; 1991 Sep; 179(3):1148-54. PubMed ID: 1930159
    [TBL] [Abstract][Full Text] [Related]  

  • 29. The amyloid peptide precursor in Alzheimer's disease.
    Octave JN
    Acta Neurol Belg; 1995 Dec; 95(4):197-209. PubMed ID: 8553793
    [TBL] [Abstract][Full Text] [Related]  

  • 30. A novel beta-site amyloid precursor protein cleaving enzyme (BACE) isoform regulated by nonsense-mediated mRNA decay and proteasome-dependent degradation.
    Tanahashi H; Tabira T
    Neurosci Lett; 2007 Nov; 428(2-3):103-8. PubMed ID: 17961921
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Human brain peptidase activity with the specificity to generate the N-terminus of the Alzheimer beta-amyloid protein from its precursor.
    McDermott JR; Biggins JA; Gibson AM
    Biochem Biophys Res Commun; 1992 Jun; 185(2):746-52. PubMed ID: 1610365
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Purification and characterization of a novel metalloprotease from human brain with the ability to cleave substrates derived from the N-terminus of beta-amyloid protein.
    Schönlein C; Löffler J; Huber G
    Biochem Biophys Res Commun; 1994 May; 201(1):45-53. PubMed ID: 8198608
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer's disease.
    Zhang Z; Song M; Liu X; Su Kang S; Duong DM; Seyfried NT; Cao X; Cheng L; Sun YE; Ping Yu S; Jia J; Levey AI; Ye K
    Nat Commun; 2015 Nov; 6():8762. PubMed ID: 26549211
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Potential roles of protease inhibitors in Alzheimer's disease.
    Abraham CR
    Neurobiol Aging; 1989; 10(5):463-5; discussion 477-8. PubMed ID: 2682323
    [TBL] [Abstract][Full Text] [Related]  

  • 35. BACE2, a beta -secretase homolog, cleaves at the beta site and within the amyloid-beta region of the amyloid-beta precursor protein.
    Farzan M; Schnitzler CE; Vasilieva N; Leung D; Choe H
    Proc Natl Acad Sci U S A; 2000 Aug; 97(17):9712-7. PubMed ID: 10931940
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Neurons derived from sporadic Alzheimer's disease iPSCs reveal elevated TAU hyperphosphorylation, increased amyloid levels, and GSK3B activation.
    Ochalek A; Mihalik B; Avci HX; Chandrasekaran A; Téglási A; Bock I; Giudice ML; Táncos Z; Molnár K; László L; Nielsen JE; Holst B; Freude K; Hyttel P; Kobolák J; Dinnyés A
    Alzheimers Res Ther; 2017 Dec; 9(1):90. PubMed ID: 29191219
    [TBL] [Abstract][Full Text] [Related]  

  • 37. A synthetic substrate assay for the gamma-secretase of the beta-A4 amyloid of Alzheimer's disease.
    Evin G; Beyreuther K; Masters CL
    J Pept Sci; 1995; 1(2):132-9. PubMed ID: 9222990
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
    Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
    Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Location of an epitope shared by Alzheimer's amyloid peptide and brain creatine kinase using a newly developed monoclonal antibody.
    Cazorla P; Aldudo J; Haas C; Vázquez J; Valdivieso F; Bullido MJ
    Biochim Biophys Acta; 1995 Apr; 1270(2-3):149-56. PubMed ID: 7537106
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Swedish mutant APP-based BACE1 binding site peptide reduces APP β-cleavage and cerebral Aβ levels in Alzheimer's mice.
    Li S; Hou H; Mori T; Sawmiller D; Smith A; Tian J; Wang Y; Giunta B; Sanberg PR; Zhang S; Tan J
    Sci Rep; 2015 Jun; 5():11322. PubMed ID: 26091071
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.