705 related articles for article (PubMed ID: 8145230)
1. Synthesis and biological evaluation of 2',3'-dideoxy-L-pyrimidine nucleosides as potential antiviral agents against human immunodeficiency virus (HIV) and hepatitis B virus (HBV).
Lin TS; Luo MZ; Liu MC; Pai SB; Dutschman GE; Cheng YC
J Med Chem; 1994 Mar; 37(6):798-803. PubMed ID: 8145230
[TBL] [Abstract][Full Text] [Related]
2. Antiviral activity of 2',3'-dideoxy-beta-L-5-fluorocytidine (beta-L-FddC) and 2',3'-dideoxy-beta-L-cytidine (beta-L-ddC) against hepatitis B virus and human immunodeficiency virus type 1 in vitro.
Lin TS; Luo MZ; Liu MC; Pai SB; Dutschman GE; Cheng YC
Biochem Pharmacol; 1994 Jan; 47(2):171-4. PubMed ID: 8304960
[TBL] [Abstract][Full Text] [Related]
3. Synthesis and anti-HIV activity of several 2'-fluoro-containing pyrimidine nucleosides.
Sterzycki RZ; Ghazzouli I; Brankovan V; Martin JC; Mansuri MM
J Med Chem; 1990 Aug; 33(8):2150-7. PubMed ID: 2165162
[TBL] [Abstract][Full Text] [Related]
4. Stereoselective synthesis and antiviral activity of D-2',3'-didehydro-2',3'-dideoxy-2'-fluoro-4'-thionucleosides.
Chong Y; Choo H; Choi Y; Mathew J; Schinazi RF; Chu CK
J Med Chem; 2002 Oct; 45(22):4888-98. PubMed ID: 12383014
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of human immunodeficiency virus type 1 reverse transcriptase by the 5'-triphosphate beta enantiomers of cytidine analogs.
Faraj A; Agrofoglio LA; Wakefield JK; McPherson S; Morrow CD; Gosselin G; Mathe C; Imbach JL; Schinazi RF; Sommadossi JP
Antimicrob Agents Chemother; 1994 Oct; 38(10):2300-5. PubMed ID: 7530932
[TBL] [Abstract][Full Text] [Related]
6. Effect of stereoisomerism on the cellular pharmacology of beta-enantiomers of cytidine analogs in Hep-G2 cells.
Martin LT; Faraj A; Schinazi RF; Gosselin G; Mathe C; Imbach JL; Sommadossi JP
Biochem Pharmacol; 1997 Jan; 53(1):75-87. PubMed ID: 8960066
[TBL] [Abstract][Full Text] [Related]
7. Anti-human immunodeficiency virus activities of the beta-L enantiomer of 2',3'-dideoxycytidine and its 5-fluoro derivative in vitro.
Gosselin G; Schinazi RF; Sommadossi JP; Mathé C; Bergogne MC; Aubertin AM; Kirn A; Imbach JL
Antimicrob Agents Chemother; 1994 Jun; 38(6):1292-7. PubMed ID: 8092827
[TBL] [Abstract][Full Text] [Related]
8. Pure nucleoside enantiomers of beta-2',3'-dideoxycytidine analogs are selective inhibitors of hepatitis B virus in vitro.
Schinazi RF; Gosselin G; Faraj A; Korba BE; Liotta DC; Chu CK; Mathé C; Imbach JL; Sommadossi JP
Antimicrob Agents Chemother; 1994 Sep; 38(9):2172-4. PubMed ID: 7811039
[TBL] [Abstract][Full Text] [Related]
9. Synthesis and antiviral activity of monofluoro and difluoro analogues of pyrimidine deoxyribonucleosides against human immunodeficiency virus (HIV-1).
Martin JA; Bushnell DJ; Duncan IB; Dunsdon SJ; Hall MJ; Machin PJ; Merrett JH; Parkes KE; Roberts NA; Thomas GJ
J Med Chem; 1990 Aug; 33(8):2137-45. PubMed ID: 2165161
[TBL] [Abstract][Full Text] [Related]
10. Effect of beta-enantiomeric and racemic nucleoside analogues on mitochondrial functions in HepG2 cells. Implications for predicting drug hepatotoxicity.
Cui L; Schinazi RF; Gosselin G; Imbach JL; Chu CK; Rando RF; Revankar GR; Sommadossi JP
Biochem Pharmacol; 1996 Nov; 52(10):1577-84. PubMed ID: 8937473
[TBL] [Abstract][Full Text] [Related]
11. N4-acyl-modified D-2',3'-dideoxy-5-fluorocytidine nucleoside analogues with improved antiviral activity.
Shi J; Mathew JS; Tharnish PM; Rachakonda S; Pai SB; Adams M; Grier JP; Gallagher K; Zhang H; Wu JT; Shi G; Geleziunas R; Erickson-Viitanen S; Stuyver L; Otto MJ; Watanabe KA; Schinazi RF
Antivir Chem Chemother; 2003 Mar; 14(2):81-90. PubMed ID: 12856919
[TBL] [Abstract][Full Text] [Related]
12. Phosphatidyl-2',3'-dideoxy-3'-thiacytidine: synthesis and antiviral activity in hepatitis B-and HIV-1-infected cells.
Xie H; Voronkov M; Liotta DC; Korba BA; Schinazi RF; Richman DD; Hostetler KY
Antiviral Res; 1995 Oct; 28(2):113-20. PubMed ID: 8585765
[TBL] [Abstract][Full Text] [Related]
13. Design and synthesis of 2',3'-dideoxy-2',3'-didehydro-beta-L-cytidine (beta-L-d4C) and 2',3'-dideoxy 2',3'-didehydro-beta-L-5-fluorocytidine (beta-L-Fd4C), two exceptionally potent inhibitors of human hepatitis B virus (HBV) and potent inhibitors of human immunodeficiency virus (HIV) in vitro.
Lin TS; Luo MZ; Liu MC; Zhu YL; Gullen E; Dutschman GE; Cheng YC
J Med Chem; 1996 Apr; 39(9):1757-9. PubMed ID: 8627596
[No Abstract] [Full Text] [Related]
14. 3'-Carbon-substituted pyrimidine nucleosides having a 2',3'-dideoxy and 2',3'-didehydro-2',3'-dideoxy structure: synthesis and antiviral evaluation.
Kumamoto H; Onuma S; Tanaka H; Dutschman GE; Cheng YC
Antivir Chem Chemother; 2006; 17(4):225-34. PubMed ID: 17066900
[TBL] [Abstract][Full Text] [Related]
15. Antiviral activity of various 1-(2'-deoxy-β-D-lyxofuranosyl), 1-(2'-fluoro-β-D-xylofuranosyl), 1-(3'-fluoro-β-D-arabinofuranosyl), and 2'-fluoro-2',3'-didehydro-2',3'-dideoxyribose pyrimidine nucleoside analogues against duck hepatitis B virus (DHBV) and human hepatitis B virus (HBV) replication.
Srivastav NC; Shakya N; Mak M; Agrawal B; Tyrrell DL; Kumar R
J Med Chem; 2010 Oct; 53(19):7156-66. PubMed ID: 20857959
[TBL] [Abstract][Full Text] [Related]
16. Influence of stereochemistry on antiviral activities and resistance profiles of dideoxycytidine nucleosides.
Van Draanen NA; Tisdale M; Parry NR; Jansen R; Dornsife RE; Tuttle JV; Averett DR; Koszalka GW
Antimicrob Agents Chemother; 1994 Apr; 38(4):868-71. PubMed ID: 7518218
[TBL] [Abstract][Full Text] [Related]
17. Synthesis and biological evaluation of 2',3'-didehydro-2',3'- dideoxy-5-fluorocytidine (D4FC) analogues: discovery of carbocyclic nucleoside triphosphates with potent inhibitory activity against HIV-1 reverse transcriptase.
Shi J; McAtee JJ; Schlueter Wirtz S; Tharnish P; Juodawlkis A; Liotta DC; Schinazi RF
J Med Chem; 1999 Mar; 42(5):859-67. PubMed ID: 10072683
[TBL] [Abstract][Full Text] [Related]
18. Comparative evaluation of L-Fd4C and related nucleoside analogs as promising antiviral agents.
Chen SH
Curr Med Chem; 2002 May; 9(9):899-912. PubMed ID: 11966452
[TBL] [Abstract][Full Text] [Related]
19. Synthesis and anti-HIV-1 activity of 2'-"up"-fluoro analogues of active anti-AIDS nucleosides 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (DDC).
Watanabe KA; Harada K; Zeidler J; Matulic-Adamic J; Takahashi K; Ren WY; Cheng LC; Fox JJ; Chou TC; Zhu QY
J Med Chem; 1990 Aug; 33(8):2145-50. PubMed ID: 1695683
[TBL] [Abstract][Full Text] [Related]
20. Chemistry and anti-HIV properties of 2'-fluoro-2',3'-dideoxyarabinofuranosylpyrimidines.
Siddiqui MA; Driscoll JS; Marquez VE; Roth JS; Shirasaka T; Mitsuya H; Barchi JJ; Kelley JA
J Med Chem; 1992 Jun; 35(12):2195-201. PubMed ID: 1351945
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]