110 related articles for article (PubMed ID: 8154332)
1. X-ray crystal structures of thrombin in complex with D-Phe-Pro-Arg and with small benzamidine- and arginine-based "non-peptidic" inhibitors.
Bode W
Adv Exp Med Biol; 1993; 340():15-26. PubMed ID: 8154332
[No Abstract] [Full Text] [Related]
2. Refined 2.3 A X-ray crystal structure of bovine thrombin complexes formed with the benzamidine and arginine-based thrombin inhibitors NAPAP, 4-TAPAP and MQPA. A starting point for improving antithrombotics.
Brandstetter H; Turk D; Hoeffken HW; Grosse D; Stürzebecher J; Martin PD; Edwards BF; Bode W
J Mol Biol; 1992 Aug; 226(4):1085-99. PubMed ID: 1518046
[TBL] [Abstract][Full Text] [Related]
3. New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK.
Martin PD; Malkowski MG; Box J; Esmon CT; Edwards BF
Structure; 1997 Dec; 5(12):1681-93. PubMed ID: 9438869
[TBL] [Abstract][Full Text] [Related]
4. The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin.
Vijayalakshmi J; Padmanabhan KP; Mann KG; Tulinsky A
Protein Sci; 1994 Dec; 3(12):2254-71. PubMed ID: 7756983
[TBL] [Abstract][Full Text] [Related]
5. Inhibition of thrombin by arginine-containing peptide chloromethyl ketones and bis chloromethyl ketone-albumin conjugates.
Odake S; Kam CM; Powers JC
J Enzyme Inhib; 1995; 9(1):17-27. PubMed ID: 8568563
[TBL] [Abstract][Full Text] [Related]
6. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
Bode W; Turk D; Karshikov A
Protein Sci; 1992 Apr; 1(4):426-71. PubMed ID: 1304349
[TBL] [Abstract][Full Text] [Related]
7. Structure and behavior of human α-thrombin upon ligand recognition: thermodynamic and molecular dynamics studies.
Silva Vde A; Cargnelutti MT; Giesel GM; Palmieri LC; Monteiro RQ; Verli H; Lima LM
PLoS One; 2011; 6(9):e24735. PubMed ID: 21935446
[TBL] [Abstract][Full Text] [Related]
8. Structural basis of thrombin-mediated factor V activation: the Glu666-Glu672 sequence is critical for processing at the heavy chain-B domain junction.
Corral-Rodríguez MÁ; Bock PE; Hernández-Carvajal E; Gutiérrez-Gallego R; Fuentes-Prior P
Blood; 2011 Jun; 117(26):7164-73. PubMed ID: 21555742
[TBL] [Abstract][Full Text] [Related]
9. Structures of the noncovalent complexes of human and bovine prothrombin fragment 2 with human PPACK-thrombin.
Arni RK; Padmanabhan K; Padmanabhan KP; Wu TP; Tulinsky A
Biochemistry; 1993 May; 32(18):4727-37. PubMed ID: 8387813
[TBL] [Abstract][Full Text] [Related]
10. Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.
Banner DW; Hadváry P
J Biol Chem; 1991 Oct; 266(30):20085-93. PubMed ID: 1939071
[TBL] [Abstract][Full Text] [Related]
11. The refined 1.9 A crystal structure of human alpha-thrombin: interaction with D-Phe-Pro-Arg chloromethylketone and significance of the Tyr-Pro-Pro-Trp insertion segment.
Bode W; Mayr I; Baumann U; Huber R; Stone SR; Hofsteenge J
EMBO J; 1989 Nov; 8(11):3467-75. PubMed ID: 2583108
[TBL] [Abstract][Full Text] [Related]
12. Structure of the non-covalent complex of prothrombin kringle 2 with PPACK-thrombin.
Arni RK; Padmanabhan K; Padmanabhan KP; Wu TP; Tulinsky A
Chem Phys Lipids; 1994 Jan; 67-68():59-66. PubMed ID: 8187245
[TBL] [Abstract][Full Text] [Related]
13. Multiple binding mode of reversible synthetic thrombin inhibitors. A comparative structural analysis.
Pavone V; De Simone G; Nastri F; Galdiero S; Staiano N; Lombardi A; Pedone C
Biol Chem; 1998; 379(8-9):987-1006. PubMed ID: 9792431
[TBL] [Abstract][Full Text] [Related]
14. Inhibitor binding to thrombin: x-ray crystallographic studies.
Banner DW; Hadváry P
Adv Exp Med Biol; 1993; 340():27-33. PubMed ID: 8154341
[No Abstract] [Full Text] [Related]
15. Crystallographic determination of the structures of human alpha-thrombin complexed with BMS-186282 and BMS-189090.
Malley MF; Tabernero L; Chang CY; Ohringer SL; Roberts DG; Das J; Sack JS
Protein Sci; 1996 Feb; 5(2):221-8. PubMed ID: 8745399
[TBL] [Abstract][Full Text] [Related]
16. Structure-based understanding of ligand affinity using human thrombin as a model system.
Nienaber VL; Mersinger LJ; Kettner CA
Biochemistry; 1996 Jul; 35(30):9690-9. PubMed ID: 8703940
[TBL] [Abstract][Full Text] [Related]
17. Design of novel types of thrombin inhibitors based on modified D-Phe-Pro-Arg sequences.
Claeson G; Elgendy S; Cheng L; Chino N; Goodwin CA; Scully MF; Deadman J
Adv Exp Med Biol; 1993; 340():83-9. PubMed ID: 8154346
[No Abstract] [Full Text] [Related]
18. Crystal structure of two new bifunctional nonsubstrate type thrombin inhibitors complexed with human alpha-thrombin.
Féthière J; Tsuda Y; Coulombe R; Konishi Y; Cygler M
Protein Sci; 1996 Jun; 5(6):1174-83. PubMed ID: 8762149
[TBL] [Abstract][Full Text] [Related]
19. Thrombomodulin Binding Selects the Catalytically Active Form of Thrombin.
Handley LD; Treuheit NA; Venkatesh VJ; Komives EA
Biochemistry; 2015 Nov; 54(43):6650-8. PubMed ID: 26468766
[TBL] [Abstract][Full Text] [Related]
20. Changes in interactions in complexes of hirudin derivatives and human alpha-thrombin due to different crystal forms.
Priestle JP; Rahuel J; Rink H; Tones M; Grütter MG
Protein Sci; 1993 Oct; 2(10):1630-42. PubMed ID: 8251938
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]