BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

81 related articles for article (PubMed ID: 8166712)

  • 1. The amino-terminal half of the cytoplasmic tail of the thyrotropin receptor is essential for full activities of receptor function.
    Kosugi S; Mori T
    Biochem Biophys Res Commun; 1994 Apr; 200(1):401-7. PubMed ID: 8166712
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Cysteine-699, a possible palmitoylation site of the thyrotropin receptor, is not crucial for cAMP or phosphoinositide signaling but is necessary for full surface expression.
    Kosugi S; Mori T
    Biochem Biophys Res Commun; 1996 Apr; 221(3):636-40. PubMed ID: 8630013
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The intracellular region adjacent to plasma membrane (residues 684-692) of the thyrotropin receptor is important for phosphoinositide signaling but not for agonist-induced adenylate cyclase activation.
    Kosugi S; Mori T
    Biochem Biophys Res Commun; 1994 Mar; 199(3):1497-503. PubMed ID: 8147896
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
    Kosugi S; Okajima F; Ban T; Hidaka A; Shenker A; Kohn LD
    Mol Endocrinol; 1993 Aug; 7(8):1009-20. PubMed ID: 7901757
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The middle portion in the second cytoplasmic loop of the thyrotropin receptor plays a crucial role in adenylate cyclase activation.
    Kosugi S; Kohn LD; Akamizu T; Mori T
    Mol Endocrinol; 1994 Apr; 8(4):498-509. PubMed ID: 7914349
    [TBL] [Abstract][Full Text] [Related]  

  • 6. [Signal transduction of the thyrotropin receptor].
    Kosugi S; Mori T
    Nihon Rinsho; 1994 Apr; 52(4):984-9. PubMed ID: 8196191
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Signal transduction by the human thyrotropin receptor: studies on the role of individual amino acid residues in the carboxyl terminal region of the third cytoplasmic loop.
    Chazenbalk GD; Nagayama Y; Wadsworth H; Russo D; Rapoport B
    Mol Endocrinol; 1991 Oct; 5(10):1523-6. PubMed ID: 1663578
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation of alanine 623 in the third cytoplasmic loop of the rat thyrotropin (TSH) receptor results in a loss in the phosphoinositide but not cAMP signal induced by TSH and receptor autoantibodies.
    Kosugi S; Okajima F; Ban T; Hidaka A; Shenker A; Kohn LD
    J Biol Chem; 1992 Dec; 267(34):24153-6. PubMed ID: 1332945
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Constitutive activation of the thyrotropin receptor by mutating CYS-636 in the sixth transmembrane segment.
    Kosugi S; Mori T
    Biochem Biophys Res Commun; 1996 May; 222(3):713-7. PubMed ID: 8651910
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Constitutive activation of cyclic AMP but not phosphatidylinositol signaling caused by four mutations in the 6th transmembrane helix of the human thyrotropin receptor.
    Kosugi S; Shenker A; Mori T
    FEBS Lett; 1994 Dec; 356(2-3):291-4. PubMed ID: 7805857
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Constitutive activation of the thyrotropin receptor by deletion of a portion of the extracellular domain.
    Zhang ML; Sugawa H; Kosugi S; Mori T
    Biochem Biophys Res Commun; 1995 Jun; 211(1):205-10. PubMed ID: 7779086
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Point mutations of the thyrotropin receptor determining structural requirements for its ability to bind thyrotropin and to stimulate adenylate cyclase activity.
    Gustavsson B; Westermark B; Heldin NE
    Biochem Biophys Res Commun; 1994 Mar; 199(2):612-8. PubMed ID: 8135801
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The first cytoplasmic loop of the thyrotropin receptor is important for phosphoinositide signaling but not for agonist-induced adenylate cyclase activation.
    Kosugi S; Mori T
    FEBS Lett; 1994 Mar; 341(2-3):162-6. PubMed ID: 8137933
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Somatic mutations in the thyrotropin receptor gene cause hyperfunctioning thyroid adenomas.
    Parma J; Duprez L; Van Sande J; Cochaux P; Gervy C; Mockel J; Dumont J; Vassart G
    Nature; 1993 Oct; 365(6447):649-51. PubMed ID: 8413627
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Identification of amino acid residues in transmembrane helices VI and VII of the lutropin/choriogonadotropin receptor involved in signaling.
    Fernandez LM; Puett D
    Biochemistry; 1996 Apr; 35(13):3986-93. PubMed ID: 8672431
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Cysteine residues are involved in structure and function of melanocortin 1 receptor: Substitution of a cysteine residue in transmembrane segment two converts an agonist to antagonist.
    Frändberg PA; Doufexis M; Kapas S; Chhajlani V
    Biochem Biophys Res Commun; 2001 Mar; 281(4):851-7. PubMed ID: 11237737
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Role of the carboxyl-terminal half of the extracellular domain of the human thyrotropin receptor in signal transduction.
    Nagayama Y; Rapoport B
    Endocrinology; 1992 Aug; 131(2):548-52. PubMed ID: 1322272
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Domain structure and signal transduction mechanisms in the thyrotropin receptor].
    Nagayama Y
    Nihon Rinsho; 1994 Apr; 52(4):979-83. PubMed ID: 8196190
    [TBL] [Abstract][Full Text] [Related]  

  • 19. The third exoplasmic loop of the thyrotropin receptor is partially involved in signal transduction.
    Kosugi S; Mori T
    FEBS Lett; 1994 Jul; 349(1):89-92. PubMed ID: 8045308
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Identification of specific intracellular domains of the human ETA receptor required for ligand binding and signal transduction.
    Hashido K; Adachi M; Gamou T; Watanabe T; Furuichi Y; Miyamoto C
    Cell Mol Biol Res; 1993; 39(1):3-12. PubMed ID: 8287069
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.