609 related articles for article (PubMed ID: 8169843)
1. Roles of cysteine conjugate beta-lyase and S-oxidase in nephrotoxicity: studies with S-(1,2-dichlorovinyl)-L-cysteine and S-(1,2-dichlorovinyl)-L-cysteine sulfoxide.
Lash LH; Sausen PJ; Duescher RJ; Cooley AJ; Elfarra AA
J Pharmacol Exp Ther; 1994 Apr; 269(1):374-83. PubMed ID: 8169843
[TBL] [Abstract][Full Text] [Related]
2. Renal cysteine conjugate C-S lyase mediated toxicity of halogenated alkenes in primary cultures of human and rat proximal tubular cells.
McGoldrick TA; Lock EA; Rodilla V; Hawksworth GM
Arch Toxicol; 2003 Jul; 77(7):365-70. PubMed ID: 12700887
[TBL] [Abstract][Full Text] [Related]
3. Quantitation of multiple pathways for the metabolism of nephrotoxic cysteine conjugates using selective inhibitors of L-alpha-hydroxy acid oxidase (L-amino acid oxidase) and cysteine conjugate beta-lyase.
Stevens JL; Hatzinger PB; Hayden PJ
Drug Metab Dispos; 1989; 17(3):297-303. PubMed ID: 2568912
[TBL] [Abstract][Full Text] [Related]
4. Sulfoxidation of mercapturic acids derived from tri- and tetrachloroethene by cytochromes P450 3A: a bioactivation reaction in addition to deacetylation and cysteine conjugate beta-lyase mediated cleavage.
Werner M; Birner G; Dekant W
Chem Res Toxicol; 1996; 9(1):41-9. PubMed ID: 8924615
[TBL] [Abstract][Full Text] [Related]
5. Uptake of nephrotoxic S-conjugates by isolated rat renal proximal tubular cells.
Lash LH; Anders MW
J Pharmacol Exp Ther; 1989 Feb; 248(2):531-7. PubMed ID: 2918469
[TBL] [Abstract][Full Text] [Related]
6. Alpha-ketoacids stimulate rat renal cysteine conjugate beta-lyase activity and potentiate the cytotoxicity of S-(1,2-dichlorovinyl)-L-cysteine.
Elfarra AA; Lash LH; Anders MW
Mol Pharmacol; 1987 Feb; 31(2):208-12. PubMed ID: 3807895
[TBL] [Abstract][Full Text] [Related]
7. Roles of necrosis, Apoptosis, and mitochondrial dysfunction in S-(1,2-dichlorovinyl)-L-cysteine sulfoxide-induced cytotoxicity in primary cultures of human renal proximal tubular cells.
Lash LH; Putt DA; Hueni SE; Krause RJ; Elfarra AA
J Pharmacol Exp Ther; 2003 Jun; 305(3):1163-72. PubMed ID: 12626654
[TBL] [Abstract][Full Text] [Related]
8. Role of cytochrome P4503A in cysteine S-conjugates sulfoxidation and the nephrotoxicity of the sevoflurane degradation product fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A) in rats.
Sheffels P; Schroeder JL; Altuntas TG; Liggitt HD; Kharasch ED
Chem Res Toxicol; 2004 Sep; 17(9):1177-89. PubMed ID: 15377151
[TBL] [Abstract][Full Text] [Related]
9. Diabetic mice are protected from normally lethal nephrotoxicity of S-1,2-dichlorovinyl-L-cysteine (DCVC): role of nephrogenic tissue repair.
Dnyanmote AV; Sawant SP; Lock EA; Latendresse JR; Warbritton AA; Mehendale HM
Toxicol Appl Pharmacol; 2006 Mar; 211(2):133-47. PubMed ID: 16125744
[TBL] [Abstract][Full Text] [Related]
10. Biotransformation, excretion, and nephrotoxicity of the hexachlorobutadiene metabolite (E)-N-acetyl-S-(1,2,3,4, 4-pentachlorobutadienyl)-L-cysteine sulfoxide.
Birner G; Werner M; Rosner E; Mehler C; Dekant W
Chem Res Toxicol; 1998 Jul; 11(7):750-7. PubMed ID: 9671537
[TBL] [Abstract][Full Text] [Related]
11. Role of tissue repair in survival from s-(1,2-dichlorovinyl)-L-cysteine-induced acute renal tubular necrosis in the mouse.
Vaidya VS; Shankar K; Lock EA; Bucci TJ; Mehendale HM
Toxicol Sci; 2003 Jul; 74(1):215-27. PubMed ID: 12730612
[TBL] [Abstract][Full Text] [Related]
12. Alkylation-induced oxidative cell injury of renal proximal tubular cells: involvement of glutathione redox-cycle inhibition.
van de Water B; Zoeteweij JP; Nagelkerke JF
Arch Biochem Biophys; 1996 Mar; 327(1):71-80. PubMed ID: 8615698
[TBL] [Abstract][Full Text] [Related]
13. Role of mitochondrial dysfunction in S-(1,2-dichlorovinyl)-l-cysteine-induced apoptosis.
Chen Y; Cai J; Anders MW; Stevens JL; Jones DP
Toxicol Appl Pharmacol; 2001 Feb; 170(3):172-80. PubMed ID: 11162782
[TBL] [Abstract][Full Text] [Related]
14. Renal cysteine conjugate beta-lyase-mediated toxicity studied with primary cultures of human proximal tubular cells.
Chen JC; Stevens JL; Trifillis AL; Jones TW
Toxicol Appl Pharmacol; 1990 May; 103(3):463-73. PubMed ID: 2339419
[TBL] [Abstract][Full Text] [Related]
15. The acute effects of S-(1,2-dichlorovinyl)-L-cysteine and related chemicals on renal function and ultrastructure in the pentobarbital-anesthetized dog: structure-activity relationships, biotransformation, and unique site-specific nephrotoxicity.
Koechel DA; Krejci ME; Ridgewell RE
Fundam Appl Toxicol; 1991 Jul; 17(1):17-33. PubMed ID: 1916074
[TBL] [Abstract][Full Text] [Related]
16. Intranephron distribution of cysteine S-conjugate beta-lyase activity and its implication for hexachloro-1,3-butadiene-induced nephrotoxicity in rats.
Kim HS; Cha SH; Abraham DG; Cooper AJ; Endou H
Arch Toxicol; 1997; 71(3):131-41. PubMed ID: 9049049
[TBL] [Abstract][Full Text] [Related]
17. Inhibition of succinate:ubiquinone reductase and decrease of ubiquinol in nephrotoxic cysteine S-conjugate-induced oxidative cell injury.
van de Water B; Zoeteweij JP; de Bont HJ; Nagelkerke JF
Mol Pharmacol; 1995 Nov; 48(5):928-37. PubMed ID: 7476924
[TBL] [Abstract][Full Text] [Related]
18. Metabolism of [14C]- and [35S]S-(1,2-dichlorovinyl)-L-cysteine in the male Fischer 344 rat.
Finkelstein MB; Patel NJ; Anders MW
Drug Metab Dispos; 1995 Jan; 23(1):124-8. PubMed ID: 7720515
[TBL] [Abstract][Full Text] [Related]
19. Human kidney flavin-containing monooxygenases and their potential roles in cysteine s-conjugate metabolism and nephrotoxicity.
Krause RJ; Lash LH; Elfarra AA
J Pharmacol Exp Ther; 2003 Jan; 304(1):185-91. PubMed ID: 12490590
[TBL] [Abstract][Full Text] [Related]
20. Changes in gene expression in human renal proximal tubule cells exposed to low concentrations of S-(1,2-dichlorovinyl)-l-cysteine, a metabolite of trichloroethylene.
Lock EA; Barth JL; Argraves SW; Schnellmann RG
Toxicol Appl Pharmacol; 2006 Oct; 216(2):319-30. PubMed ID: 16844155
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
