BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

171 related articles for article (PubMed ID: 8174204)

  • 1. Biochemical and antitumor activity of trimidox, a new inhibitor of ribonucleotide reductase.
    Szekeres T; Gharehbaghi K; Fritzer M; Woody M; Srivastava A; van't Riet B; Jayaram HN; Elford HL
    Cancer Chemother Pharmacol; 1994; 34(1):63-6. PubMed ID: 8174204
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Enhanced effects of adriamycin by combination with a new ribonucleotide reductase inhibitor, trimidox, in murine leukemia.
    Fritzer-Szekeres M; Novotny L; Romanova D; Göbl R; Sedlak J; Vachalkova A; Rauko P; Elford HL; Szekeres T
    Life Sci; 1998; 63(7):545-52. PubMed ID: 9718080
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Hydroxyurea and trimidox enhance the radiation effect in human pancreatic adenocarcinoma cells.
    Leyden D; Ahmed N; Hassan HT
    Anticancer Res; 2000; 20(1A):133-8. PubMed ID: 10769645
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The ribonucleotide reductase inhibitor trimidox induces c-myc and apoptosis of human ovarian carcinoma cells.
    Rosenberger G; Fuhrmann G; Grusch M; Fassl S; Elford HL; Smid K; Peters GJ; Szekeres T; Krupitza G
    Life Sci; 2000 Nov; 67(26):3131-42. PubMed ID: 11191620
    [TBL] [Abstract][Full Text] [Related]  

  • 5. [The ribonucleotide reductase enzyme as a target for enzyme-directed chemotherapy effects of trimidox (3,4,5-trihydroxybenzohydroxamidoxim), a new inhibitor of ribonucleotide reductases].
    Findenig G; Vielnascher E; Göbl R; Fritzer-Szekeres M; Szekeres T
    Wien Klin Wochenschr; 1995; 107(22):694-7. PubMed ID: 8533431
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Trimidox, an inhibitor of ribonucleotide reductase, synergistically enhances the inhibition of colony formation by Ara-C in HL-60 human promyelocytic leukemia cells.
    Fritzer-Szekeres M; Salamon A; Grusch M; Horvath Z; Höchtl T; Steinbrugger R; Jäger W; Krupitza G; Elford HL; Szekeres T
    Biochem Pharmacol; 2002 Aug; 64(3):481-5. PubMed ID: 12147300
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Enhancement of hemoglobin and F-cell production by targeting growth inhibition and differentiation of K562 cells with ribonucleotide reductase inhibitors (didox and trimidox) in combination with streptozotocin.
    Iyamu WE; Adunyah SE; Fasold H; Horiuchi K; Elford HL; Asakura T; Turner EA
    Am J Hematol; 2000 Apr; 63(4):176-83. PubMed ID: 10706760
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Iron binding capacity of trimidox (3,4,5-trihydroxybenzamidoxime), a new inhibitor of the enzyme ribonucleotide reductase.
    Szekeres T; Vielnascher E; Novotny L; Vachalkova A; Fritzer M; Findenig G; Göbl R; Elford HL; Goldenberg H
    Eur J Clin Chem Clin Biochem; 1995 Nov; 33(11):785-9. PubMed ID: 8620054
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Trimidox, an inhibitor of ribonucleotide reductase, induces apoptosis and activates caspases in HL-60 promyelocytic leukemia cells.
    Fritzer-Szekeres M; Grusch M; Luxbacher C; Horvath S; Krupitza G; Elford HL; Szekeres T
    Exp Hematol; 2000 Aug; 28(8):924-30. PubMed ID: 10989193
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Potentiation of the activity of cisplatin and cyclophosphamide by trimidox, a novel ribonucleotide reductase inhibitor, in leukemia-bearing mice.
    Novotny L; Rauko P; Liska J; Elford HL; Szekeres T
    Cancer Lett; 2006 Feb; 233(1):178-84. PubMed ID: 15885888
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Interaction of gallium nitrate with other inhibitors of ribonucleotide reductase: effects on the proliferation of human leukemic cells.
    Myette MS; Elford HL; Chitambar CR
    Cancer Lett; 1998 Jul; 129(2):199-204. PubMed ID: 9719462
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Suppression of retrovirus-induced immunodeficiency disease (murine AIDS) by trimidox and didox: novel ribonucleotide reductase inhibitors with less bone marrow toxicity than hydroxyurea.
    Mayhew CN; Mampuru LJ; Chendil D; Ahmed MM; Phillips JD; Greenberg RN; Elford HL; Gallicchio VS
    Antiviral Res; 2002 Nov; 56(2):167-81. PubMed ID: 12367722
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synergistic growth inhibitory and differentiating effects of trimidox and tiazofurin in human promyelocytic leukemia HL-60 cells.
    Szekeres T; Fritzer M; Strobl H; Gharehbaghi K; Findenig G; Elford HL; Lhotka C; Schoen HJ; Jayaram HN
    Blood; 1994 Dec; 84(12):4316-21. PubMed ID: 7994048
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Triapine (3-aminopyridine-2-carboxaldehyde- thiosemicarbazone): A potent inhibitor of ribonucleotide reductase activity with broad spectrum antitumor activity.
    Finch RA; Liu M; Grill SP; Rose WC; Loomis R; Vasquez KM; Cheng Y; Sartorelli AC
    Biochem Pharmacol; 2000 Apr; 59(8):983-91. PubMed ID: 10692563
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Characterization of mouse leukemia L1210 cells resistant to the ribonucleotide reductase inhibitor 4-methyl-5-amino-1-formylisoquinoline thiosemicarbazone.
    Cory AH; Sato A; Thompson DP; Cory JG
    Oncol Res; 1996; 8(10-11):449-56. PubMed ID: 9114437
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Trimidox-mediated morphological changes during erythroid differentiation is associated with the stimulation of hemoglobin and F-cell production in human K562 cells.
    Iyamu EW; Adunyah SE; Elford HL; Fasold H; Turner EA
    Biochem Biophys Res Commun; 1998 Jun; 247(3):759-64. PubMed ID: 9647767
    [TBL] [Abstract][Full Text] [Related]  

  • 17. In vivo and in vitro comparison of the short-term hematopoietic toxicity between hydroxyurea and trimidox or didox, novel ribonucleotide reductase inhibitors with potential anti-HIV-1 activity.
    Mayhew CN; Phillips JD; Greenberg RN; Birch NJ; Elford HL; Gallicchio VS
    Stem Cells; 1999; 17(6):345-56. PubMed ID: 10606163
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ribonucleotide reductase inhibitors hydroxyurea, didox, and trimidox inhibit human cytomegalovirus replication in vitro and synergize with ganciclovir.
    Bhave S; Elford H; McVoy MA
    Antiviral Res; 2013 Oct; 100(1):151-8. PubMed ID: 23933116
    [TBL] [Abstract][Full Text] [Related]  

  • 19. [Synergistic cytotoxic effects of chemotherapy in colon tumor cells by simultaneous inhibition of de novo and salvage energy metabolism pathways].
    Szekeres T; Fritzer M; Schön HJ; Findenig G; Lhotka C
    Wien Klin Wochenschr; 1994; 106(14):459-63. PubMed ID: 7941593
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combination of inhibitors of lymphocyte activation (hydroxyurea, trimidox, and didox) and reverse transcriptase (didanosine) suppresses development of murine retrovirus-induced lymphoproliferative disease.
    Mayhew CN; Sumpter R; Inayat M; Cibull M; Phillips JD; Elford HL; Gallicchio VS
    Antiviral Res; 2005 Jan; 65(1):13-22. PubMed ID: 15652967
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.