BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

122 related articles for article (PubMed ID: 8175705)

  • 21. Coordinated activation of the Rac-GAP β2-chimaerin by an atypical proline-rich domain and diacylglycerol.
    Gutierrez-Uzquiza A; Colon-Gonzalez F; Leonard TA; Canagarajah BJ; Wang H; Mayer BJ; Hurley JH; Kazanietz MG
    Nat Commun; 2013; 4():1849. PubMed ID: 23673634
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Nonsense mutations in the C-terminal SH2 region of the GTPase activating protein (GAP) gene in human tumours.
    Friedman E; Gejman PV; Martin GA; McCormick F
    Nat Genet; 1993 Nov; 5(3):242-7. PubMed ID: 8275088
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Promoter region of the transcriptional unit for human alpha 1-chimaerin, a neuron-specific GTPase-activating protein for p21rac.
    Dong JM; Smith P; Hall C; Lim L
    Eur J Biochem; 1995 Feb; 227(3):636-46. PubMed ID: 7867622
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Bcr encodes a GTPase-activating protein for p21rac.
    Diekmann D; Brill S; Garrett MD; Totty N; Hsuan J; Monfries C; Hall C; Lim L; Hall A
    Nature; 1991 May; 351(6325):400-2. PubMed ID: 1903516
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Tyrosine phosphorylation of beta2-chimaerin by Src-family kinase negatively regulates its Rac-specific GAP activity.
    Kai M; Yasuda S; Imai S; Kanoh H; Sakane F
    Biochim Biophys Acta; 2007 Sep; 1773(9):1407-15. PubMed ID: 17560670
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Identification of an autoinhibitory mechanism that restricts C1 domain-mediated activation of the Rac-GAP alpha2-chimaerin.
    Colón-González F; Leskow FC; Kazanietz MG
    J Biol Chem; 2008 Dec; 283(50):35247-57. PubMed ID: 18826946
    [TBL] [Abstract][Full Text] [Related]  

  • 27. p23/Tmp21 differentially targets the Rac-GAP beta2-chimaerin and protein kinase C via their C1 domains.
    Wang H; Kazanietz MG
    Mol Biol Cell; 2010 Apr; 21(8):1398-408. PubMed ID: 20164256
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Phorbol ester and hydrogen peroxide synergistically induce the interaction of diacylglycerol kinase gamma with the Src homology 2 and C1 domains of beta2-chimaerin.
    Yasuda S; Kai M; Imai S; Kanoh H; Sakane F
    Biochem J; 2008 Jan; 409(1):95-106. PubMed ID: 17803461
    [TBL] [Abstract][Full Text] [Related]  

  • 29. A non-receptor tyrosine kinase that inhibits the GTPase activity of p21cdc42.
    Manser E; Leung T; Salihuddin H; Tan L; Lim L
    Nature; 1993 May; 363(6427):364-7. PubMed ID: 8497321
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Phosphorylation of the ras GTPase-activating protein (GAP) by the p93c-fes protein-tyrosine kinase in vitro and formation of GAP-fes complexes via an SH2 domain-dependent mechanism.
    Hjermstad SJ; Briggs SD; Smithgall TE
    Biochemistry; 1993 Oct; 32(39):10519-25. PubMed ID: 7691175
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Plant cell growth and differentiation may involve GAP regulation of Rac activity.
    Borg S; Pødenphant L; Jensen TJ; Poulsen C
    FEBS Lett; 1999 Jun; 453(3):341-5. PubMed ID: 10405172
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Biochemical characterization of hyperactive beta2-chimaerin mutants revealed an enhanced exposure of C1 and Rac-GAP domains.
    Sosa MS; Lewin NE; Choi SH; Blumberg PM; Kazanietz MG
    Biochemistry; 2009 Sep; 48(34):8171-8. PubMed ID: 19618918
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Bridging Ral GTPase to Rho pathways. RLIP76, a Ral effector with CDC42/Rac GTPase-activating protein activity.
    Jullien-Flores V; Dorseuil O; Romero F; Letourneur F; Saragosti S; Berger R; Tavitian A; Gacon G; Camonis JH
    J Biol Chem; 1995 Sep; 270(38):22473-7. PubMed ID: 7673236
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Identification of a truncated β1-chimaerin variant that inactivates nuclear Rac1.
    Casado-Medrano V; Barrio-Real L; Gutiérrez-Miranda L; González-Sarmiento R; Velasco EA; Kazanietz MG; Caloca MJ
    J Biol Chem; 2020 Jan; 295(5):1300-1314. PubMed ID: 31871052
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Functional interactions between isolated SH2 domains and insulin/Ras signaling pathways of Xenopus oocytes: opposite effects of the carboxy- and amino-terminal SH2 domains of p85 PI 3-kinase.
    Aroca P; Mahadevan D; Santos E
    Oncogene; 1996 Nov; 13(9):1839-46. PubMed ID: 8934529
    [TBL] [Abstract][Full Text] [Related]  

  • 36. A new member of the ras superfamily, the rac1 homologue from Caenorhabditis elegans. Cloning and sequence analysis of cDNA, pattern of developmental expression, and biochemical characterization of the protein.
    Chen W; Lim HH; Lim L
    J Biol Chem; 1993 Jan; 268(1):320-4. PubMed ID: 7677998
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Comparative study of p120 GTPase-activating protein and its point mutant in the pleckstrin homology domain.
    Nakata H; Watanabe Y
    Cell Signal; 1998 Mar; 10(3):211-6. PubMed ID: 9607145
    [TBL] [Abstract][Full Text] [Related]  

  • 38. A GTPase-activating protein for rhoB p20, a ras p21-like GTP-binding protein--partial purification, characterization and subcellular distribution in rat brain.
    Yamamoto J; Kikuchi A; Ueda T; Ohga N; Takai Y
    Brain Res Mol Brain Res; 1990 Jul; 8(2):105-11. PubMed ID: 2169565
    [TBL] [Abstract][Full Text] [Related]  

  • 39. A Ras-GTPase-activating protein SH3-domain-binding protein.
    Parker F; Maurier F; Delumeau I; Duchesne M; Faucher D; Debussche L; Dugue A; Schweighoffer F; Tocque B
    Mol Cell Biol; 1996 Jun; 16(6):2561-9. PubMed ID: 8649363
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Inhibition of aggressiveness of metastatic mouse mammary carcinoma cells by the beta2-chimaerin GAP domain.
    Menna PL; Skilton G; Leskow FC; Alonso DF; Gomez DE; Kazanietz MG
    Cancer Res; 2003 May; 63(9):2284-91. PubMed ID: 12727851
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 7.