222 related articles for article (PubMed ID: 8179482)
1. Metabolic activation of aromatic and heterocyclic N-hydroxyarylamines by wild-type and mutant recombinant human NAT1 and NAT2 acetyltransferases.
Hein DW; Rustan TD; Ferguson RJ; Doll MA; Gray K
Arch Toxicol; 1994; 68(2):129-33. PubMed ID: 8179482
[TBL] [Abstract][Full Text] [Related]
2. Metabolic activation and deactivation of arylamine carcinogens by recombinant human NAT1 and polymorphic NAT2 acetyltransferases.
Hein DW; Doll MA; Rustan TD; Gray K; Feng Y; Ferguson RJ; Grant DM
Carcinogenesis; 1993 Aug; 14(8):1633-8. PubMed ID: 8353847
[TBL] [Abstract][Full Text] [Related]
3. Metabolic activation of N-hydroxyarylamines and N-hydroxyarylamides by 16 recombinant human NAT2 allozymes: effects of 7 specific NAT2 nucleic acid substitutions.
Hein DW; Doll MA; Rustan TD; Ferguson RJ
Cancer Res; 1995 Aug; 55(16):3531-6. PubMed ID: 7627960
[TBL] [Abstract][Full Text] [Related]
4. Metabolic activation of heterocyclic aromatic amines catalyzed by human arylamine N-acetyltransferase isozymes (NAT1 and NAT2) expressed in Salmonella typhimurium.
Wild D; Feser W; Michel S; Lord HL; Josephy PD
Carcinogenesis; 1995 Mar; 16(3):643-8. PubMed ID: 7697826
[TBL] [Abstract][Full Text] [Related]
5. Metabolic activation of N-hydroxy-2-aminofluorene and N-hydroxy-2-acetylaminofluorene by monomorphic N-acetyltransferase (NAT1) and polymorphic N-acetyltransferase (NAT2) in colon cytosols of Syrian hamsters congenic at the NAT2 locus.
Hein DW; Doll MA; Gray K; Rustan TD; Ferguson RJ
Cancer Res; 1993 Feb; 53(3):509-14. PubMed ID: 8425184
[TBL] [Abstract][Full Text] [Related]
6. N-acetyltransferase expression and metabolic activation of the food-derived heterocyclic amines in the human mammary gland.
Sadrieh N; Davis CD; Snyderwine EG
Cancer Res; 1996 Jun; 56(12):2683-7. PubMed ID: 8665493
[TBL] [Abstract][Full Text] [Related]
7. The effect of the rs1799931 G857A (G286E) polymorphism on N-acetyltransferase 2-mediated carcinogen metabolism and genotoxicity differs with heterocyclic amine exposure.
Hein DW; Salazar-González RA; Doll MA; Zang Y
Arch Toxicol; 2023 Oct; 97(10):2697-2705. PubMed ID: 37592049
[TBL] [Abstract][Full Text] [Related]
8. Cloning, sequencing, and recombinant expression of NAT1, NAT2, and NAT3 derived from the C3H/HeJ (rapid) and A/HeJ (slow) acetylator inbred mouse: functional characterization of the activation and deactivation of aromatic amine carcinogens.
Fretland AJ; Doll MA; Gray K; Feng Y; Hein DW
Toxicol Appl Pharmacol; 1997 Feb; 142(2):360-6. PubMed ID: 9070359
[TBL] [Abstract][Full Text] [Related]
9. Construction of Syrian hamster lines congenic at the polymorphic acetyltransferase locus (NAT2): acetylator genotype-dependent N- and O-acetylation of arylamine carcinogens.
Hein DW; Doll MA; Rustan TD; Gray K; Ferguson RJ; Feng Y
Toxicol Appl Pharmacol; 1994 Jan; 124(1):16-24. PubMed ID: 8291057
[TBL] [Abstract][Full Text] [Related]
10. Metabolic activation of carcinogenic heterocyclic aromatic amines by human liver and colon.
Turesky RJ; Lang NP; Butler MA; Teitel CH; Kadlubar FF
Carcinogenesis; 1991 Oct; 12(10):1839-45. PubMed ID: 1934265
[TBL] [Abstract][Full Text] [Related]
11. Recombinant rat and hamster N-acetyltransferases-1 and -2: relative rates of N-acetylation of arylamines and N,O-acyltransfer with arylhydroxamic acids.
Jones RF; Land SJ; King CM
Carcinogenesis; 1996 Aug; 17(8):1729-33. PubMed ID: 8761433
[TBL] [Abstract][Full Text] [Related]
12. Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells.
Stone EM; Williams JA; Grover PL; Gusterson BA; Phillips DH
Carcinogenesis; 1998 May; 19(5):873-9. PubMed ID: 9635877
[TBL] [Abstract][Full Text] [Related]
13. Heterologous expression of human N-acetyltransferases 1 and 2 and sulfotransferase 1A1 in Salmonella typhimurium for mutagenicity testing of heterocyclic amines.
Muckel E; Frandsen H; Glatt HR
Food Chem Toxicol; 2002 Aug; 40(8):1063-8. PubMed ID: 12067565
[TBL] [Abstract][Full Text] [Related]
14. Structure-function studies of human arylamine N-acetyltransferases NAT1 and NAT2. Functional analysis of recombinant NAT1/NAT2 chimeras expressed in Escherichia coli.
Dupret JM; Goodfellow GH; Janezic SA; Grant DM
J Biol Chem; 1994 Oct; 269(43):26830-5. PubMed ID: 7929420
[TBL] [Abstract][Full Text] [Related]
15. Human
Hein DW; Doll MA; Habil MR
Front Pharmacol; 2022; 13():821133. PubMed ID: 35281898
[TBL] [Abstract][Full Text] [Related]
16. In vitro bioactivation of N-hydroxy-2-amino-alpha-carboline.
King RS; Teitel CH; Kadlubar FF
Carcinogenesis; 2000 Jul; 21(7):1347-54. PubMed ID: 10874013
[TBL] [Abstract][Full Text] [Related]
17. Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis.
Hein DW
Mutat Res; 2002 Sep; 506-507():65-77. PubMed ID: 12351146
[TBL] [Abstract][Full Text] [Related]
18. Identification and characterization of functional rat arylamine N-acetyltransferase 3: comparisons with rat arylamine N-acetyltransferases 1 and 2.
Walraven JM; Doll MA; Hein DW
J Pharmacol Exp Ther; 2006 Oct; 319(1):369-75. PubMed ID: 16829624
[TBL] [Abstract][Full Text] [Related]
19. 4-Aminobiphenyl downregulation of NAT2 acetylator genotype-dependent N- and O-acetylation of aromatic and heterocyclic amine carcinogens in primary mammary epithelial cell cultures from rapid and slow acetylator rats.
Jefferson FA; Xiao GH; Hein DW
Toxicol Sci; 2009 Jan; 107(1):293-7. PubMed ID: 18842621
[TBL] [Abstract][Full Text] [Related]
20. N-and O-acetylation of aromatic and heterocyclic amine carcinogens by human monomorphic and polymorphic acetyltransferases expressed in COS-1 cells.
Minchin RF; Reeves PT; Teitel CH; McManus ME; Mojarrabi B; Ilett KF; Kadlubar FF
Biochem Biophys Res Commun; 1992 Jun; 185(3):839-44. PubMed ID: 1627140
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
