These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

61 related articles for article (PubMed ID: 8181515)

  • 1. Mutagenesis of the human interleukin-6 fourth predicted alpha-helix: involvement of the Arg168 in the binding site.
    Fontaine V; Ooms J; Content J
    Eur J Immunol; 1994 May; 24(5):1041-5. PubMed ID: 8181515
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Structure-function analysis of human IL-6: identification of two distinct regions that are important for receptor binding.
    Hammacher A; Ward LD; Weinstock J; Treutlein H; Yasukawa K; Simpson RJ
    Protein Sci; 1994 Dec; 3(12):2280-93. PubMed ID: 7538847
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Folding topologies of human interleukin-6 and its mutants as studied by NMR spectroscopy.
    Nishimura C; Watanabe A; Gouda H; Shimada I; Arata Y
    Biochemistry; 1996 Jan; 35(1):273-81. PubMed ID: 8555185
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Engineering human interleukin-6 to obtain variants with strongly enhanced bioactivity.
    Toniatti C; Cabibbo A; Sporena E; Salvati AL; Cerretani M; Serafini S; Lahm A; Cortese R; Ciliberto G
    EMBO J; 1996 Jun; 15(11):2726-37. PubMed ID: 8654370
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Site-directed mutagenesis of N-linked glycosylation sites on the gamma-aminobutyric acid type A receptor alpha 1 subunit.
    Buller AL; Hastings GA; Kirkness EF; Fraser CM
    Mol Pharmacol; 1994 Nov; 46(5):858-65. PubMed ID: 7969072
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Effects of site-specific mutations on biologic activities of recombinant human IL-6.
    Snouwaert JN; Kariya K; Fowlkes DM
    J Immunol; 1991 Jan; 146(2):585-91. PubMed ID: 1987278
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Substitutions at the Glu62 residue of human interleukin-2 differentially affect its binding to the alpha chain and the beta gamma complex of the interleukin-2 receptor.
    Wang Z; Zheng Z; Sun L; Liu X
    Eur J Immunol; 1995 May; 25(5):1212-6. PubMed ID: 7774625
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structure-function studies of the C-terminal alpha-helix of human interleukin-2 by site-directed mutagenesis.
    Xu D; Jiang C; Shi Y; Yu J; Sun L; Fan P; Liu X
    Chin J Biotechnol; 1993; 9(4):229-34. PubMed ID: 8061231
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of the Arg179 in the active site of human IL-6.
    Fontaine V; Savino R; Arcone R; de Wit L; Brakenhoff JP; Content J; Ciliberto G
    Eur J Biochem; 1993 Feb; 211(3):749-55. PubMed ID: 8436132
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Reversal of some viral IL-6 electrostatic properties compared to IL-6 contributes to a loss of alpha receptor component recruitment.
    Perret D; Rousseau F; Tran V; Gascan H
    Proteins; 2005 Jul; 60(1):14-26. PubMed ID: 15861391
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of two novel regions of human IL-6 responsible for receptor binding and signal transduction.
    Ehlers M; Grötzinger J; deHon FD; Müllberg J; Brakenhoff JP; Liu J; Wollmer A; Rose-John S
    J Immunol; 1994 Aug; 153(4):1744-53. PubMed ID: 7519211
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mapping of receptor binding sites on IL-1 beta by reconstruction of IL-1ra-like domains.
    Boraschi D; Bossù P; Ruggiero P; Tagliabue A; Bertini R; Macchia G; Gasbarro C; Pellegrini L; Melillo G; Ulisse E; Visconti U; Bizzarri C; Del Grosso E; Mackay AR; Frascotti G; Frigerio F; Grifantini R; Grandi G
    J Immunol; 1995 Nov; 155(10):4719-25. PubMed ID: 7594472
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The human IL-11 receptor requires gp130 for signalling: demonstration by molecular cloning of the receptor.
    Nandurkar HH; Hilton DJ; Nathan P; Willson T; Nicola N; Begley CG
    Oncogene; 1996 Feb; 12(3):585-93. PubMed ID: 8637716
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Site-directed mutagenesis of the putative distal helix of peroxygenase cytochrome P450.
    Matsunaga I; Ueda A; Sumimoto T; Ichihara K; Ayata M; Ogura H
    Arch Biochem Biophys; 2001 Oct; 394(1):45-53. PubMed ID: 11566026
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of the C-terminus in the activity, conformation, and stability of interleukin-6.
    Ward LD; Hammacher A; Zhang JG; Weinstock J; Yasukawa K; Morton CJ; Norton RS; Simpson RJ
    Protein Sci; 1993 Sep; 2(9):1472-81. PubMed ID: 8401231
    [TBL] [Abstract][Full Text] [Related]  

  • 16. XylS-Pm promoter interactions through two helix-turn-helix motifs: identifying XylS residues important for DNA binding and activation.
    Domínguez-Cuevas P; Marín P; Marqués S; Ramos JL
    J Mol Biol; 2008 Jan; 375(1):59-69. PubMed ID: 18005985
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Solution structure of recombinant human interleukin-6.
    Xu GY; Yu HA; Hong J; Stahl M; McDonagh T; Kay LE; Cumming DA
    J Mol Biol; 1997 May; 268(2):468-81. PubMed ID: 9159484
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Toward understanding the role of insulin alpha-helix II in the growth-promoting activity of insulin.
    Chen H; Feng YM
    Biol Chem; 2001 Jul; 382(7):1057-62. PubMed ID: 11530936
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Analysis of human/mouse interleukin-6 hybrid proteins: both amino and carboxy termini of human interleukin-6 are required for in vitro receptor binding.
    Fiorillo MT; Cabibbo A; Iacopetti P; Fattori E; Ciliberto G
    Eur J Immunol; 1992 Oct; 22(10):2609-15. PubMed ID: 1396966
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Functional and receptor binding characterization of recombinant murine macrophage inflammatory protein 2: sequence analysis and mutagenesis identify receptor binding epitopes.
    Jerva LF; Sullivan G; Lolis E
    Protein Sci; 1997 Aug; 6(8):1643-52. PubMed ID: 9260277
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 4.