285 related articles for article (PubMed ID: 8185666)
1. Demonstration of a direct effect on hepatic acyl CoA: cholesterol acyl transferase (ACAT) activity by an orally administered enzyme inhibitor in the hamster.
Burrier RE; Deren S; McGregor DG; Hoos LM; Smith AA; Davis HR
Biochem Pharmacol; 1994 Apr; 47(9):1545-51. PubMed ID: 8185666
[TBL] [Abstract][Full Text] [Related]
2. Pharmacological profile of F 12511, (S)-2',3', 5'-trimethyl-4'-hydroxy-alpha-dodecylthioacetanilide a powerful and systemic acylcoenzyme A: cholesterol acyltransferase inhibitor.
Junquero D; Oms P; Carilla-Durand E; Autin J; Tarayre J; Degryse A; Patoiseau J; Colpaert FC; Delhon A
Biochem Pharmacol; 2001 Jan; 61(1):97-108. PubMed ID: 11137714
[TBL] [Abstract][Full Text] [Related]
3. Relationship between bioavailability and hypocholesterolemic activity of YM17E, an inhibitor of ACAT, in cholesterol-fed rats.
Uchida T; Aoyama K; Watanabe T; Higuchi S
Atherosclerosis; 1998 Mar; 137(1):97-106. PubMed ID: 9568741
[TBL] [Abstract][Full Text] [Related]
4. TMP-153, a novel ACAT inhibitor, inhibits cholesterol absorption and lowers plasma cholesterol in rats and hamsters.
Sugiyama Y; Ishikawa E; Odaka H; Miki N; Tawada H; Ikeda H
Atherosclerosis; 1995 Feb; 113(1):71-8. PubMed ID: 7755657
[TBL] [Abstract][Full Text] [Related]
5. Regulation of hepatic cholesterol ester hydrolase and acyl-coenzyme A:cholesterol acyltransferase in the rat.
Stone BG; Evans CD; Fadden RJ; Schreiber D
J Lipid Res; 1989 Nov; 30(11):1681-90. PubMed ID: 2614270
[TBL] [Abstract][Full Text] [Related]
6. Effect of SMP-500, a novel acyl-coA:cholesterol acyltransferase inhibitor, on the cholesterol esterification and its hypocholesterolemic properties.
Ioriya K; Noguchi T; Muraoka M; Fujita K; Shimizu H; Ohashi N
Pharmacology; 2002 May; 65(1):18-25. PubMed ID: 11901297
[TBL] [Abstract][Full Text] [Related]
7. A selective inhibitor of intestinal ACAT, EAB309 suppresses both intestinal and hepatic cholesterol output and stimulates chylomicron removal.
Umeda Y; Hirano T; Kako Y; Kamagata K; Okuyama K; Suzuki K
Life Sci; 1998; 63(13):PL187-95. PubMed ID: 9763214
[TBL] [Abstract][Full Text] [Related]
8. The hypolipidemic action of the ACAT inhibitor HL-004 in hamsters fed normal chow.
Murakami S; Ohta Y; Asami Y; Yamagishi I; Toda Y; Sato M; Tomisawa K
Gen Pharmacol; 1996 Dec; 27(8):1383-6. PubMed ID: 9304411
[TBL] [Abstract][Full Text] [Related]
9. Plasma cholesterol reducing effect of FR129169, a novel acyl-CoA:cholesterol acyltransferase inhibitor, in the rat.
Sakuma Y; Hagihara H; Ohne K; Nagayoshi A; Mutoh S; Ito Y; Notsu Y; Okuhara M
Jpn J Pharmacol; 1996 Jan; 70(1):35-41. PubMed ID: 8822087
[TBL] [Abstract][Full Text] [Related]
10. The effect of acyl CoA: cholesterol acyltransferase inhibition on the uptake, esterification and secretion of cholesterol by the hamster small intestine.
Burrier RE; Smith AA; McGregor DG; Hoos LM; Zilli DL; Davis HR
J Pharmacol Exp Ther; 1995 Jan; 272(1):156-63. PubMed ID: 7815329
[TBL] [Abstract][Full Text] [Related]
11. The effects of simvastatin and cholestyramine, alone and in combination, on hepatic cholesterol metabolism in the male rat. off.
Shand JH; West DW
Lipids; 1995 Oct; 30(10):917-26. PubMed ID: 8538379
[TBL] [Abstract][Full Text] [Related]
12. On the mechanism by which an ACAT inhibitor (CL 277,082) influences plasma lipoproteins in the rat.
Balasubramaniam S; Simons LA; Chang S; Roach PD; Nestel PJ
Atherosclerosis; 1990 May; 82(1-2):1-5. PubMed ID: 2360913
[TBL] [Abstract][Full Text] [Related]
13. Lack of correlation between ACAT mRNA expression and cholesterol esterification in primary liver cells.
Rea TJ; DeMattos RB; Homan R; Newton RS; Pape ME
Biochim Biophys Acta; 1996 Jan; 1299(1):67-74. PubMed ID: 8555254
[TBL] [Abstract][Full Text] [Related]
14. Pharmacological properties of YM17E, an acyl-CoA:cholesterol acyltransferase inhibitor, and diarrheal effect in beagle dogs.
Kashiwa M; Masuyama Y; Miyauchi H; Uchida T; Naganuma S; Kakuta H; Terada M; Kiriyama T; Matsuda K; Ito N; Iizumi Y; Takenaka T
Jpn J Pharmacol; 1997 Jan; 73(1):41-50. PubMed ID: 9032133
[TBL] [Abstract][Full Text] [Related]
15. Hypolipidemic and antioxidant activity of the novel acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor KY-455 in rabbits and hamsters.
Nakamura S; Kamiya S; Shirahase H; Kanda M; Yoshimi A; Tarumi T; Kurahashi K
Arzneimittelforschung; 2004; 54(2):102-8. PubMed ID: 15038459
[TBL] [Abstract][Full Text] [Related]
16. Hypolipidaemic properties of a potent and bioavailable alkylsulphinyl-diphenylimidazole ACAT inhibitor (RP 73163) in animals fed diets low in cholesterol.
Riddell D; Bright CP; Burton BJ; Bush RC; Harris NV; Hele D; Moore UM; Naik K; Parrott DP; Smith C; Williams RJ
Biochem Pharmacol; 1996 Oct; 52(8):1177-86. PubMed ID: 8937424
[TBL] [Abstract][Full Text] [Related]
17. Dietary fatty acids regulate acyl-CoA:cholesterol acyltransferase and cytosolic cholesteryl ester hydrolase in hamsters.
Lee JY; Carr TP
J Nutr; 2004 Dec; 134(12):3239-44. PubMed ID: 15570019
[TBL] [Abstract][Full Text] [Related]
18. Divergent pharmacologic activities of PD 132301-2 and CL 277,082, urea inhibitors of acyl-CoA:cholesterol acyltransferase.
Krause BR; Black A; Bousley R; Essenburg A; Cornicelli J; Holmes A; Homan R; Kieft K; Sekerke C; Shaw-Hes MK
J Pharmacol Exp Ther; 1993 Nov; 267(2):734-43. PubMed ID: 8246149
[TBL] [Abstract][Full Text] [Related]
19. Protein phosphatase 1 and 2A inhibitors activate acyl-CoA:cholesterol acyltransferase and cholesterol ester formation in isolated rat hepatocytes.
Hernández ML; Martínez MJ; López de Heredia M; Ochoa B
Biochim Biophys Acta; 1997 Nov; 1349(3):233-41. PubMed ID: 9434137
[TBL] [Abstract][Full Text] [Related]
20. Influence of the acyl-CoA: cholesterol O-acyltransferase inhibitor, CL 277082, on cholesteryl ester accumulation in rabbit macrophage-rich granulomas and hepatic tissue.
Kelley JL; Suenram CA; Rozek MM; Schaffer SA; Schwartz CJ
Biochim Biophys Acta; 1988 May; 960(1):83-90. PubMed ID: 3358947
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]