285 related articles for article (PubMed ID: 8185666)
21. Human acyl-CoA:cholesterol acyltransferase (ACAT) and its potential as a target for pharmaceutical intervention against atherosclerosis.
Chang C; Dong R; Miyazaki A; Sakashita N; Zhang Y; Liu J; Guo M; Li BL; Chang TY
Acta Biochim Biophys Sin (Shanghai); 2006 Mar; 38(3):151-6. PubMed ID: 16518538
[TBL] [Abstract][Full Text] [Related]
22. TMP-153, a novel ACAT inhibitor, lowers plasma cholesterol through its hepatic action in golden hamsters.
Sugiyama Y; Odaka H; Itokawa S; Ishikawa E; Tomari Y; Ikeda H
Atherosclerosis; 1995 Nov; 118(1):145-53. PubMed ID: 8579624
[TBL] [Abstract][Full Text] [Related]
23. ACAT inhibitor HL-004 accelerates the regression of hypercholesterolemia in stroke-prone spontaneously hypertensive rats (SHRSP): stimulation of bile acid production by HL-004.
Murakami S; Yamagishi I; Sato M; Tomisawa K; Nara Y; Yamori Y
Atherosclerosis; 1997 Aug; 133(1):97-104. PubMed ID: 9258412
[TBL] [Abstract][Full Text] [Related]
24. Determination of hepatic acyl-coenzyme A-cholesterol acyltransferase activity in LPN hamsters: a model for cholesterol gallstone formation.
Smith JL; Lutton C
J Gastroenterol Hepatol; 1997 Dec; 12(12):877-86. PubMed ID: 9504901
[TBL] [Abstract][Full Text] [Related]
25. Inhibitors of acyl-CoA: cholesterol O-acyl transferase (ACAT) as hypocholesterolemic agents. 6. The first water-soluble ACAT inhibitor with lipid-regulating activity.
Sliskovic DR; Krause BR; Picard JA; Anderson M; Bousley RF; Hamelehle KL; Homan R; Julian TN; Rashidbaigi ZA; Stanfield RL
J Med Chem; 1994 Mar; 37(5):560-2. PubMed ID: 8126693
[No Abstract] [Full Text] [Related]
26. RP 64477: a potent inhibitor of acyl-coenzyme A:cholesterol O-acyltransferase with low systemic bioavailability.
Bello AA; Bright C; Burton BJ; Bush RC; Casey JH; Dron DI; Facchini V; Joannou PP; Parrott DP; Riddell D; Roberts SA; Williams RJ
Biochem Pharmacol; 1996 Feb; 51(4):413-21. PubMed ID: 8619885
[TBL] [Abstract][Full Text] [Related]
27. Relationships between lipophilicity and biological activities in a series of indoline-based anti-oxidative acyl-CoA:cholesterol acyltransferase (ACAT) inhibitors.
Takahashi K; Kunishiro K; Kasai M; Miike T; Kurahashi K; Shirahase H
Arzneimittelforschung; 2008; 58(12):666-72. PubMed ID: 19202739
[TBL] [Abstract][Full Text] [Related]
28. Effect of the acyl-CoA:cholesterol acyltransferase inhibitor, E5324, on experimental atherosclerosis in rabbits.
Tanaka H; Ohtsuka I; Kogushi M; Kimura T; Fujimori T; Saeki T; Hayashi K; Kobayashi H; Yamada T; Hiyoshi H
Atherosclerosis; 1994 Jun; 107(2):187-201. PubMed ID: 7980693
[TBL] [Abstract][Full Text] [Related]
29. Hepatic zonation of the formation and hydrolysis of cholesteryl esters in periportal and perivenous parenchymal cells.
Romero JR; Fresnedo O; Isusi E; Barrionuevo J; Ochoa B
Lipids; 1999 Sep; 34(9):907-13. PubMed ID: 10574654
[TBL] [Abstract][Full Text] [Related]
30. Inhibition of acyl coenzyme A:cholesterol acyltransferase blocks esterification but not uptake of cholesterol in Caco-2 cells.
Ellsworth JL; Starr JR
Metabolism; 1998 Mar; 47(3):325-32. PubMed ID: 9500571
[TBL] [Abstract][Full Text] [Related]
31. Inhibitory effect of monatepil maleate on acyl-CoA:cholesterol acyltransferase activity in the liver of cholesterol-fed Japanese monkeys.
Sumiya T; Ikeno A; Kato H; Fujitani B; Masuda Y; Hosoki K; Miyazaki M
Am J Hypertens; 1997 Jul; 10(7 Pt 1):779-85. PubMed ID: 9234833
[TBL] [Abstract][Full Text] [Related]
32. [Effect of F-1394, a potent and selective inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT), on esterification of cholesterol and basolateral secretion of cholesteryl ester in Caco-2 cells].
Kusunoki J; Aragane K; Kitamine T; Yamaura T; Ohnishi H
Nihon Yakurigaku Zasshi; 1997 Dec; 110(6):357-65. PubMed ID: 9503394
[TBL] [Abstract][Full Text] [Related]
33. Effects of F-1394, an acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor, on ACAT activity in HepG2 cells and on hepatic secretion of lipids in Triton WR-1339-induced hyperlipidemic rats: possible role of hepatic ACAT in very low density lipoprotein secretion.
Aragane K; Kusunoki J; Kitamine T; Yamaura T; Ohnishi H
Jpn J Pharmacol; 1998 Mar; 76(3):309-12. PubMed ID: 9593225
[TBL] [Abstract][Full Text] [Related]
34. In vivo evidence that the lipid-regulating activity of the ACAT inhibitor CI-976 in rats is due to inhibition of both intestinal and liver ACAT.
Krause BR; Anderson M; Bisgaier CL; Bocan T; Bousley R; DeHart P; Essenburg A; Hamelehle K; Homan R; Kieft K
J Lipid Res; 1993 Feb; 34(2):279-94. PubMed ID: 8429262
[TBL] [Abstract][Full Text] [Related]
35. CL 277,082: a novel inhibitor of ACAT-catalyzed cholesterol esterification and cholesterol absorption.
Largis EE; Wang CH; DeVries VG; Schaffer SA
J Lipid Res; 1989 May; 30(5):681-90. PubMed ID: 2760542
[TBL] [Abstract][Full Text] [Related]
36. Inhibitory effects of oren-gedoku-to and its components on cholesteryl ester synthesis in cultured human hepatocyte HepG2 cells: evidence from the cultured HepG2 cells and in vitro assay of ACAT.
Yotsumoto H; Yanagita T; Yamamoto K; Ogawa Y; Cha JY; Mori Y
Planta Med; 1997 Apr; 63(2):141-5. PubMed ID: 9140228
[TBL] [Abstract][Full Text] [Related]
37. Inhibition of cholesterol esterification by DuP 128 decreases hepatic apolipoprotein B secretion in vivo: effect of dietary fat and cholesterol.
Burnett JR; Wilcox LJ; Telford DE; Kleinstiver SJ; Barrett PH; Huff MW
Biochim Biophys Acta; 1998 Jul; 1393(1):63-79. PubMed ID: 9714740
[TBL] [Abstract][Full Text] [Related]
38. Pharmacological properties of R-755, a novel acyl-CoA:cholesterol acyltransferase inhibitor, in cholesterol-fed rats, hamsters and rabbits.
Matsui Y; Horiuchi K; Yamamoto K; Kanai K
Jpn J Pharmacol; 2001 Apr; 85(4):423-33. PubMed ID: 11388647
[TBL] [Abstract][Full Text] [Related]
39. Overexpression of SR-BI in hamsters treated with a novel ACAT inhibitor (F12511).
Milliat F; Férézou J; Delhon A; Lutton C
C R Acad Sci III; 2001 Mar; 324(3):229-34. PubMed ID: 11291309
[TBL] [Abstract][Full Text] [Related]
40. Acyl-coenzyme A:cholesterol acyltransferase inhibitor, avasimibe, stimulates bile acid synthesis and cholesterol 7alpha-hydroxylase in cultured rat hepatocytes and in vivo in the rat.
Post SM; Zoeteweij JP; Bos MH; de Wit EC; Havinga R; Kuipers F; Princen HM
Hepatology; 1999 Aug; 30(2):491-500. PubMed ID: 10421659
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]