BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

247 related articles for article (PubMed ID: 8196603)

  • 1. Role of IRS-1-GRB-2 complexes in insulin signaling.
    Myers MG; Wang LM; Sun XJ; Zhang Y; Yenush L; Schlessinger J; Pierce JH; White MF
    Mol Cell Biol; 1994 Jun; 14(6):3577-87. PubMed ID: 8196603
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Association between GRB2/Sos and insulin receptor substrate 1 is not sufficient for activation of extracellular signal-regulated kinases by interleukin-4: implications for Ras activation by insulin.
    Pruett W; Yuan Y; Rose E; Batzer AG; Harada N; Skolnik EY
    Mol Cell Biol; 1995 Mar; 15(3):1778-85. PubMed ID: 7862167
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Insulin receptor substrate 1 rescues insulin action in CHO cells expressing mutant insulin receptors that lack a juxtamembrane NPXY motif.
    Chen D; Van Horn DJ; White MF; Backer JM
    Mol Cell Biol; 1995 Sep; 15(9):4711-7. PubMed ID: 7651388
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Role of SH-PTP2, a protein-tyrosine phosphatase with Src homology 2 domains, in insulin-stimulated Ras activation.
    Noguchi T; Matozaki T; Horita K; Fujioka Y; Kasuga M
    Mol Cell Biol; 1994 Oct; 14(10):6674-82. PubMed ID: 7935386
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Comparison of the insulin and insulin-like growth factor 1 mitogenic intracellular signaling pathways.
    Sasaoka T; Ishiki M; Sawa T; Ishihara H; Takata Y; Imamura T; Usui I; Olefsky JM; Kobayashi M
    Endocrinology; 1996 Oct; 137(10):4427-34. PubMed ID: 8828504
    [TBL] [Abstract][Full Text] [Related]  

  • 6. The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc: implications for insulin control of ras signalling.
    Skolnik EY; Lee CH; Batzer A; Vicentini LM; Zhou M; Daly R; Myers MJ; Backer JM; Ullrich A; White MF
    EMBO J; 1993 May; 12(5):1929-36. PubMed ID: 8491186
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Insulin stimulates association of insulin receptor substrate-1 with the protein abundant Src homology/growth factor receptor-bound protein 2.
    Tobe K; Matuoka K; Tamemoto H; Ueki K; Kaburagi Y; Asai S; Noguchi T; Matsuda M; Tanaka S; Hattori S
    J Biol Chem; 1993 May; 268(15):11167-71. PubMed ID: 8388384
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Interactive roles of Ras, insulin receptor substrate-1, and proteins with Src homology-2 domains in insulin signaling in Xenopus oocytes.
    Chuang LM; Hausdorff SF; Myers MG; White MF; Birnbaum MJ; Kahn CR
    J Biol Chem; 1994 Nov; 269(44):27645-9. PubMed ID: 7961682
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Increased insulin sensitivity in IGF-I receptor--deficient brown adipocytes.
    Mur C; Valverde AM; Kahn CR; Benito M
    Diabetes; 2002 Mar; 51(3):743-54. PubMed ID: 11872675
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Insulin receptor substrate (IRS) proteins IRS-1 and IRS-2 differential signaling in the insulin/insulin-like growth factor-I pathways in fetal brown adipocytes.
    Valverde AM; Lorenzo M; Pons S; White MF; Benito M
    Mol Endocrinol; 1998 May; 12(5):688-97. PubMed ID: 9605931
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stimulation of protein synthesis, eukaryotic translation initiation factor 4E phosphorylation, and PHAS-I phosphorylation by insulin requires insulin receptor substrate 1 and phosphatidylinositol 3-kinase.
    Mèndez R; Myers MG; White MF; Rhoads RE
    Mol Cell Biol; 1996 Jun; 16(6):2857-64. PubMed ID: 8649395
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Functional importance of Shc tyrosine 317 on insulin signaling in Rat1 fibroblasts expressing insulin receptors.
    Ishihara H; Sasaoka T; Ishiki M; Takata Y; Imamura T; Usui I; Langlois WJ; Sawa T; Kobayashi M
    J Biol Chem; 1997 Apr; 272(14):9581-6. PubMed ID: 9083103
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Association of insulin receptor substrate 1 (IRS-1) y895 with Grb-2 mediates the insulin signaling involved in IRS-1-deficient brown adipocyte mitogenesis.
    Valverde AM; Mur C; Pons S; Alvarez AM; White MF; Kahn CR; Benito M
    Mol Cell Biol; 2001 Apr; 21(7):2269-80. PubMed ID: 11259577
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Neoplastic transformation induced by insulin receptor substrate-1 overexpression requires an interaction with both Grb2 and Syp signaling molecules.
    Tanaka S; Ito T; Wands JR
    J Biol Chem; 1996 Jun; 271(24):14610-6. PubMed ID: 8662827
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different pathways of postreceptor desensitization following chronic insulin treatment and in cells overexpressing constitutively active insulin receptors.
    Inoue G; Cheatham B; Kahn CR
    J Biol Chem; 1996 Nov; 271(45):28206-11. PubMed ID: 8910437
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insulin receptor substrate-1 enhances growth hormone-induced proliferation.
    Liang L; Zhou T; Jiang J; Pierce JH; Gustafson TA; Frank SJ
    Endocrinology; 1999 May; 140(5):1972-83. PubMed ID: 10218944
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Growth hormone-promoted tyrosyl phosphorylation of SHC proteins and SHC association with Grb2.
    VanderKuur J; Allevato G; Billestrup N; Norstedt G; Carter-Su C
    J Biol Chem; 1995 Mar; 270(13):7587-93. PubMed ID: 7535773
    [TBL] [Abstract][Full Text] [Related]  

  • 18. PTEN inhibits insulin-stimulated MEK/MAPK activation and cell growth by blocking IRS-1 phosphorylation and IRS-1/Grb-2/Sos complex formation in a breast cancer model.
    Weng LP; Smith WM; Brown JL; Eng C
    Hum Mol Genet; 2001 Mar; 10(6):605-16. PubMed ID: 11230180
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Systematic mapping of potential binding sites for Shc and Grb2 SH2 domains on insulin receptor substrate-1 and the receptors for insulin, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factor.
    Ward CW; Gough KH; Rashke M; Wan SS; Tribbick G; Wang J
    J Biol Chem; 1996 Mar; 271(10):5603-9. PubMed ID: 8621421
    [TBL] [Abstract][Full Text] [Related]  

  • 20. A complex of GRB2-dynamin binds to tyrosine-phosphorylated insulin receptor substrate-1 after insulin treatment.
    Ando A; Yonezawa K; Gout I; Nakata T; Ueda H; Hara K; Kitamura Y; Noda Y; Takenawa T; Hirokawa N
    EMBO J; 1994 Jul; 13(13):3033-8. PubMed ID: 8039498
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.