These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

98 related articles for article (PubMed ID: 8200078)

  • 1. Strong intensification of mouse hepatic tamoxifen DNA adduct formation by pretreatment with the sulfotransferase inhibitor and ubiquitous environmental pollutant pentachlorophenol.
    Randerath K; Bi J; Mabon N; Sriram P; Moorthy B
    Carcinogenesis; 1994 May; 15(5):797-800. PubMed ID: 8200078
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Tamoxifen: evidence by 32P-postlabeling and use of metabolic inhibitors for two distinct pathways leading to mouse hepatic DNA adduct formation and identification of 4-hydroxytamoxifen as a proximate metabolite.
    Randerath K; Moorthy B; Mabon N; Sriram P
    Carcinogenesis; 1994 Oct; 15(10):2087-94. PubMed ID: 7955037
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Evidence from 32P-postlabeling and the use of pentachlorophenol for a novel metabolic activation pathway of diethylstilbestrol and its dimethyl ether in mouse live: likely alpha-hydroxylation of ethyl group(s) followed by sulfate conjugation.
    Moorthy B; Liehr J; Randerath E; Randerath K
    Carcinogenesis; 1995 Nov; 16(11):2643-8. PubMed ID: 7586180
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Pentachlorophenol enhances 9-hydroxybenzo [a] pyrene-induced hepatic DNA adduct formation in vivo and inhibits microsomal epoxide hydrolase and glutathione S-transferase activities in vitro: likely inhibition of epoxide detoxication by pentachlorophenol.
    Moorthy B; Randerath K
    Arch Toxicol; 1996; 70(11):696-703. PubMed ID: 8896715
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Tamoxifen-DNA adduct formation in rat liver determined by immunoassay and 32P-postlabeling.
    Divi RL; Osborne MR; Hewer A; Phillips DH; Poirier MC
    Cancer Res; 1999 Oct; 59(19):4829-33. PubMed ID: 10519392
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Role of sulfation in the formation of DNA adducts from N-hydroxy-2-acetylaminofluorene in rat liver in vivo. Inhibition of N-acetylated aminofluorene adduct formation by pentachlorophenol.
    Meerman JH; Beland FA; Mulder GJ
    Carcinogenesis; 1981; 2(5):413-6. PubMed ID: 7273322
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Tamoxifen metabolic activation: comparison of DNA adducts formed by microsomal and chemical activation of tamoxifen and 4-hydroxytamoxifen with DNA adducts formed in vivo.
    Moorthy B; Sriram P; Pathak DN; Bodell WJ; Randerath K
    Cancer Res; 1996 Jan; 56(1):53-7. PubMed ID: 8548775
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Microsomal and peroxidase activation of 4-hydroxy-tamoxifen to form DNA adducts: comparison with DNA adducts formed in Sprague-Dawley rats treated with tamoxifen.
    Pathak DN; Pongracz K; Bodell WJ
    Carcinogenesis; 1995 Jan; 16(1):11-5. PubMed ID: 7834794
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Major role of hepatic sulfotransferase activity in the metabolic activation, DNA adduct formation, and carcinogenicity of 1'-hydroxy-2',3'-dehydroestragole in infant male C57BL/6J x C3H/HeJ F1 mice.
    Fennell TR; Wiseman RW; Miller JA; Miller EC
    Cancer Res; 1985 Nov; 45(11 Pt 1):5310-20. PubMed ID: 3863702
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Co-chromatography of a tamoxifen epoxide-deoxyguanylic acid adduct with a major DNA adduct formed in the livers of tamoxifen-treated rats.
    Phillips DH; Hewer A; White IN; Farmer PB
    Carcinogenesis; 1994 May; 15(5):793-5. PubMed ID: 8200077
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Sex differences in the activation of tamoxifen to DNA binding species in rat liver in vivo and in rat hepatocytes in vitro: role of sulfotransferase induction.
    Davis W; Hewer A; Rajkowski KM; Meinl W; Glatt H; Phillips DH
    Cancer Res; 2000 Jun; 60(11):2887-91. PubMed ID: 10850433
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Hepatic macromolecular covalent binding of the hepatocarcinogen 2,6-dinitrotoluene and its 2,4-isomer in vivo: modulation by the sulfotransferase inhibitors pentachlorophenol and 2,6-dichloro-4-nitrophenol.
    Kedderis GL; Dyroff MC; Rickert DE
    Carcinogenesis; 1984 Sep; 5(9):1199-204. PubMed ID: 6590136
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of glutathione depletion and inhibition of glucuronidation and sulfation on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) metabolism, PhIP-DNA adduct formation and unscheduled DNA synthesis in primary rat hepatocytes.
    Kaderlik KR; Mulder GJ; Shaddock JG; Casciano DA; Teitel CH; Kadlubar FF
    Carcinogenesis; 1994 Aug; 15(8):1711-6. PubMed ID: 8055653
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The role of sulfation in the metabolic activation of N-hydroxy-4'-fluoro-4-acetylaminobiphenyl.
    van de Poll ML; Tijdens RB; Vondrácek P; Bruins AP; Meijer DK; Meerman JH
    Carcinogenesis; 1989 Dec; 10(12):2285-91. PubMed ID: 2480190
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 32P-post-labelling analysis of DNA adducts formed in the livers of animals treated with safrole, estragole and other naturally-occurring alkenylbenzenes. I. Adult female CD-1 mice.
    Randerath K; Haglund RE; Phillips DH; Reddy MV
    Carcinogenesis; 1984 Dec; 5(12):1613-22. PubMed ID: 6499112
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Initiation of hepatocarcinogenesis in infant male B6C3F1 mice by N-hydroxy-2-aminofluorene or N-hydroxy-2-acetylaminofluorene depends primarily on metabolism to N-sulfooxy-2-aminofluorene and formation of DNA-(deoxyguanosin-8-yl)-2-aminofluorene adducts.
    Lai CC; Miller EC; Miller JA; Liem A
    Carcinogenesis; 1987 Mar; 8(3):471-8. PubMed ID: 3815742
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Age- and sex-related differences in activation of the carcinogen 7-hydroxymethyl-12-methylbenz[a]anthracene to an electrophilic sulfuric acid ester metabolite in rats. Possible involvement of hydroxysteroid sulfotransferase activity.
    Surh YJ; Liem A; Miller EC; Miller JA
    Biochem Pharmacol; 1991 Jan; 41(2):213-21. PubMed ID: 1824923
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Activation of the tamoxifen derivative metabolite E to form DNA adducts: comparison with the adducts formed by microsomal activation of tamoxifen.
    Pongracz K; Pathak DN; Nakamura T; Burlingame AL; Bodell WJ
    Cancer Res; 1995 Jul; 55(14):3012-5. PubMed ID: 7606720
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Rat, but not human, sulfotransferase activates a tamoxifen metabolite to produce DNA adducts and gene mutations in bacteria and mammalian cells in culture.
    Glatt H; Davis W; Meinl W; Hermersdörfer H; Venitt S; Phillips DH
    Carcinogenesis; 1998 Oct; 19(10):1709-13. PubMed ID: 9806149
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 32P-postlabeling analysis of DNA adduction in mice by synthetic metabolites of the environmental carcinogen, 7H-dibenzo[c,g]carbazole: chromatographic evidence for 3-hydroxy-7H-dibenzo[c,g]carbazole being a proximate genotoxicant in liver but not skin.
    Schurdak ME; Stong DB; Warshawsky D; Randerath K
    Carcinogenesis; 1987 Apr; 8(4):591-7. PubMed ID: 3829321
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 5.