BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

1713 related articles for article (PubMed ID: 8209258)

  • 1. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation.
    Gurney ME; Pu H; Chiu AY; Dal Canto MC; Polchow CY; Alexander DD; Caliendo J; Hentati A; Kwon YW; Deng HX
    Science; 1994 Jun; 264(5166):1772-5. PubMed ID: 8209258
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutant mice, Cu,Zn superoxide dismutase, and motor neuron degeneration.
    McCord JM
    Science; 1994 Dec; 266(5190):1586-7. PubMed ID: 7985031
    [No Abstract]   [Full Text] [Related]  

  • 3. The Golgi apparatus of spinal cord motor neurons in transgenic mice expressing mutant Cu,Zn superoxide dismutase becomes fragmented in early, preclinical stages of the disease.
    Mourelatos Z; Gonatas NK; Stieber A; Gurney ME; Dal Canto MC
    Proc Natl Acad Sci U S A; 1996 May; 93(11):5472-7. PubMed ID: 8643599
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Human Cu/Zn superoxide dismutase (SOD1) overexpression in mice causes mitochondrial vacuolization, axonal degeneration, and premature motoneuron death and accelerates motoneuron disease in mice expressing a familial amyotrophic lateral sclerosis mutant SOD1.
    Jaarsma D; Haasdijk ED; Grashorn JA; Hawkins R; van Duijn W; Verspaget HW; London J; Holstege JC
    Neurobiol Dis; 2000 Dec; 7(6 Pt B):623-43. PubMed ID: 11114261
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Interleukin-6 Deficiency Does Not Affect Motor Neuron Disease Caused by Superoxide Dismutase 1 Mutation.
    Han Y; Ripley B; Serada S; Naka T; Fujimoto M
    PLoS One; 2016; 11(4):e0153399. PubMed ID: 27070121
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Mouse motor neuron disease caused by truncated SOD1 with or without C-terminal modification.
    Watanabe Y; Yasui K; Nakano T; Doi K; Fukada Y; Kitayama M; Ishimoto M; Kurihara S; Kawashima M; Fukuda H; Adachi Y; Inoue T; Nakashima K
    Brain Res Mol Brain Res; 2005 Apr; 135(1-2):12-20. PubMed ID: 15857664
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vivo quantification of spinal and bulbar motor neuron degeneration in the G93A-SOD1 transgenic mouse model of ALS by T2 relaxation time and apparent diffusion coefficient.
    Niessen HG; Angenstein F; Sander K; Kunz WS; Teuchert M; Ludolph AC; Heinze HJ; Scheich H; Vielhaber S
    Exp Neurol; 2006 Oct; 201(2):293-300. PubMed ID: 16740261
    [TBL] [Abstract][Full Text] [Related]  

  • 8. An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria.
    Wong PC; Pardo CA; Borchelt DR; Lee MK; Copeland NG; Jenkins NA; Sisodia SS; Cleveland DW; Price DL
    Neuron; 1995 Jun; 14(6):1105-16. PubMed ID: 7605627
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Fibrillar inclusions and motor neuron degeneration in transgenic mice expressing superoxide dismutase 1 with a disrupted copper-binding site.
    Wang J; Xu G; Gonzales V; Coonfield M; Fromholt D; Copeland NG; Jenkins NA; Borchelt DR
    Neurobiol Dis; 2002 Jul; 10(2):128-38. PubMed ID: 12127151
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Early decrease of redox factor-1 in spinal motor neurons of presymptomatic transgenic mice with a mutant SOD1 gene.
    Manabe Y; Warita H; Murakami T; Shiote M; Hayashi T; Nagano I; Shoji M; Abe K
    Brain Res; 2001 Oct; 915(1):104-7. PubMed ID: 11578626
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Familial amyotrophic lateral sclerosis with a novel G85S mutation of superoxide dismutase 1 gene: clinical features of lower motor neuron disease.
    Takazawa T; Ikeda K; Hirayama T; Kawabe K; Nakamura Y; Ito H; Kano O; Yoshii Y; Tanaka F; Sobue G; Iwasaki Y
    Intern Med; 2010; 49(2):183-6. PubMed ID: 20075587
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Endosomal accumulation of APP in wobbler motor neurons reflects impaired vesicle trafficking: implications for human motor neuron disease.
    Palmisano R; Golfi P; Heimann P; Shaw C; Troakes C; Schmitt-John T; Bartsch JW
    BMC Neurosci; 2011 Mar; 12():24. PubMed ID: 21385376
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Superoxide dismutase activity in lymphoblastoid cells from motor neurone disease/amyotrophic lateral sclerosis (MND/ALS) patients.
    Garofalo O; Figlewicz DA; Thomas SM; Butler R; Lebuis L; Rouleau G; Meininger V; Leigh PN
    J Neurol Sci; 1995 May; 129 Suppl():90-2. PubMed ID: 7595631
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Transgenic mice expressing an altered murine superoxide dismutase gene provide an animal model of amyotrophic lateral sclerosis.
    Ripps ME; Huntley GW; Hof PR; Morrison JH; Gordon JW
    Proc Natl Acad Sci U S A; 1995 Jan; 92(3):689-93. PubMed ID: 7846037
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Aggregation of mutant Cu/Zn superoxide dismutase proteins in a culture model of ALS.
    Durham HD; Roy J; Dong L; Figlewicz DA
    J Neuropathol Exp Neurol; 1997 May; 56(5):523-30. PubMed ID: 9143265
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Neuregulin 1 confers neuroprotection in SOD1-linked amyotrophic lateral sclerosis mice via restoration of C-boutons of spinal motor neurons.
    Lasiene J; Komine O; Fujimori-Tonou N; Powers B; Endo F; Watanabe S; Shijie J; Ravits J; Horner P; Misawa H; Yamanaka K
    Acta Neuropathol Commun; 2016 Feb; 4():15. PubMed ID: 26891847
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu,Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS).
    Dal Canto MC; Gurney ME
    Brain Res; 1995 Apr; 676(1):25-40. PubMed ID: 7796176
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS.
    Higgins CM; Jung C; Ding H; Xu Z
    J Neurosci; 2002 Mar; 22(6):RC215. PubMed ID: 11886899
    [TBL] [Abstract][Full Text] [Related]  

  • 19. ALS-linked Cu/Zn-SOD mutation increases vulnerability of motor neurons to excitotoxicity by a mechanism involving increased oxidative stress and perturbed calcium homeostasis.
    Kruman II; Pedersen WA; Springer JE; Mattson MP
    Exp Neurol; 1999 Nov; 160(1):28-39. PubMed ID: 10630188
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mutant SOD1 linked to familial amyotrophic lateral sclerosis, but not wild-type SOD1, induces ER stress in COS7 cells and transgenic mice.
    Tobisawa S; Hozumi Y; Arawaka S; Koyama S; Wada M; Nagai M; Aoki M; Itoyama Y; Goto K; Kato T
    Biochem Biophys Res Commun; 2003 Apr; 303(2):496-503. PubMed ID: 12659845
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 86.