800 related articles for article (PubMed ID: 8214760)
1. Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane, and methoxyflurane.
Kharasch ED; Thummel KE
Anesthesiology; 1993 Oct; 79(4):795-807. PubMed ID: 8214760
[TBL] [Abstract][Full Text] [Related]
2. Human kidney methoxyflurane and sevoflurane metabolism. Intrarenal fluoride production as a possible mechanism of methoxyflurane nephrotoxicity.
Kharasch ED; Hankins DC; Thummel KE
Anesthesiology; 1995 Mar; 82(3):689-99. PubMed ID: 7879937
[TBL] [Abstract][Full Text] [Related]
3. Human liver microsomal enflurane defluorination catalyzed by cytochrome P-450 2E1.
Thummel KE; Kharasch ED; Podoll T; Kunze K
Drug Metab Dispos; 1993; 21(2):350-7. PubMed ID: 8097708
[TBL] [Abstract][Full Text] [Related]
4. Metabolism by rat hepatic microsomes of fluorinated ether anesthetics following ethanol consumption.
Rice SA; Dooley JR; Mazze RI
Anesthesiology; 1983 Mar; 58(3):237-41. PubMed ID: 6829959
[TBL] [Abstract][Full Text] [Related]
5. Biotransformation of sevoflurane.
Kharasch ED
Anesth Analg; 1995 Dec; 81(6 Suppl):S27-38. PubMed ID: 7486145
[TBL] [Abstract][Full Text] [Related]
6. Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes.
Clarke SE; Baldwin SJ; Bloomer JC; Ayrton AD; Sozio RS; Chenery RJ
Chem Res Toxicol; 1994; 7(6):836-42. PubMed ID: 7696540
[TBL] [Abstract][Full Text] [Related]
7. Metabolism by rat hepatic microsomes of fluorinated ether anesthetics following isoniazid administration.
Rice SA; Sbordone L; Mazze RI
Anesthesiology; 1980 Dec; 53(6):489-93. PubMed ID: 7457965
[TBL] [Abstract][Full Text] [Related]
8. P450-dependent and nonenzymatic human liver microsomal defluorination of fluoromethyl-2,2-difluoro-1-(trifluoromethyl)vinyl ether (compound A), a sevoflurane degradation product.
Kharasch ED; Hankins DC
Drug Metab Dispos; 1996 Jun; 24(6):649-54. PubMed ID: 8781780
[TBL] [Abstract][Full Text] [Related]
9. Stereoselective metabolism of enflurane by human liver cytochrome P450 2E1.
Garton KJ; Yuen P; Meinwald J; Thummel KE; Kharasch ED
Drug Metab Dispos; 1995 Dec; 23(12):1426-30. PubMed ID: 8689955
[TBL] [Abstract][Full Text] [Related]
10. Clinical sevoflurane metabolism and disposition. II. The role of cytochrome P450 2E1 in fluoride and hexafluoroisopropanol formation.
Kharasch ED; Armstrong AS; Gunn K; Artru A; Cox K; Karol MD
Anesthesiology; 1995 Jun; 82(6):1379-88. PubMed ID: 7793652
[TBL] [Abstract][Full Text] [Related]
11. Effect of phenytoin (DPH) treatment on methoxyflurane metabolism in rats.
Caughey GH; Rice SA; Kosek JC; Mazze RI
J Pharmacol Exp Ther; 1979 Aug; 210(2):180-5. PubMed ID: 458627
[TBL] [Abstract][Full Text] [Related]
12. Role of cytochrome P450 2E1 in the metabolism of 1,1,2,3,3,3-hexafluoropropyl methyl ether.
Köster U; Speerschneider P; Kerssebaum R; Wittmann H; Dekant W
Drug Metab Dispos; 1994; 22(5):667-72. PubMed ID: 7835215
[TBL] [Abstract][Full Text] [Related]
13. Effect of streptozotocin-induced diabetes in the rat on the metabolism of fluorinated volatile anesthetics.
Pantuck EJ; Pantuck CB; Conney AH
Anesthesiology; 1987 Jan; 66(1):24-8. PubMed ID: 3541691
[TBL] [Abstract][Full Text] [Related]
14. Clinical enflurane metabolism by cytochrome P450 2E1.
Kharasch ED; Thummel KE; Mautz D; Bosse S
Clin Pharmacol Ther; 1994 Apr; 55(4):434-40. PubMed ID: 8162670
[TBL] [Abstract][Full Text] [Related]
15. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
Spracklin DK; Thummel KE; Kharasch ED
Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
[TBL] [Abstract][Full Text] [Related]
16. Ethanol-inducible cytochrome P450 in rabbits metabolizes enflurane.
Hoffman J; Konopka K; Buckhorn C; Koop DR; Waskell L
Br J Anaesth; 1989 Jul; 63(1):103-8. PubMed ID: 2765333
[TBL] [Abstract][Full Text] [Related]
17. Enflurane, isoflurane, and methoxyflurane metabolism in rat hepatic microsomes from ethanol-treated animals.
Van Dyke RA
Anesthesiology; 1983 Mar; 58(3):221-4. PubMed ID: 6829956
[TBL] [Abstract][Full Text] [Related]
18. Cytochrome P450 2E1 is the principal catalyst of human oxidative halothane metabolism in vitro.
Spracklin DK; Hankins DC; Fisher JM; Thummel KE; Kharasch ED
J Pharmacol Exp Ther; 1997 Apr; 281(1):400-11. PubMed ID: 9103523
[TBL] [Abstract][Full Text] [Related]
19. Kinetic analysis of the activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by heterologously expressed human P450 enzymes and the effect of P450-specific chemical inhibitors on this activation in human liver microsomes.
Patten CJ; Smith TJ; Murphy SE; Wang MH; Lee J; Tynes RE; Koch P; Yang CS
Arch Biochem Biophys; 1996 Sep; 333(1):127-38. PubMed ID: 8806763
[TBL] [Abstract][Full Text] [Related]
20. Metabolism of synthane: comparison with in vivo and in vitro defluorination of other halogenated hydrocarbon anaesthetics.
Mazze RI; Beppu WJ; Hitt BA
Br J Anaesth; 1979 Sep; 51(9):839-44. PubMed ID: 508489
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
