BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

157 related articles for article (PubMed ID: 8216347)

  • 1. NADPH-dependent enzyme-catalyzed reduction of aldophosphamide, the pivotal metabolite of cyclophosphamide.
    Parekh HK; Sladek NE
    Biochem Pharmacol; 1993 Sep; 46(6):1043-52. PubMed ID: 8216347
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Relative contribution of human erythrocyte aldehyde dehydrogenase to the systemic detoxification of the oxazaphosphorines.
    Dockham PA; Sreerama L; Sladek NE
    Drug Metab Dispos; 1997 Dec; 25(12):1436-41. PubMed ID: 9394035
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Identification of human liver aldehyde dehydrogenases that catalyze the oxidation of aldophosphamide and retinaldehyde.
    Dockham PA; Lee MO; Sladek NE
    Biochem Pharmacol; 1992 Jun; 43(11):2453-69. PubMed ID: 1610409
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of the mouse aldehyde dehydrogenases important in aldophosphamide detoxification.
    Manthey CL; Landkamer GJ; Sladek NE
    Cancer Res; 1990 Aug; 50(16):4991-5002. PubMed ID: 2379164
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Kinetic characterization of the catalysis of "activated" cyclophosphamide (4-hydroxycyclophosphamide/aldophosphamide) oxidation to carboxyphosphamide by mouse hepatic aldehyde dehydrogenases.
    Manthey CL; Sladek NE
    Biochem Pharmacol; 1988 Jul; 37(14):2781-90. PubMed ID: 3395357
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potentiation of the cytotoxic action of mafosfamide by N-isopropyl-p-formylbenzamide, a metabolite of procarbazine.
    Maki PA; Sladek NE
    Cancer Res; 1991 Aug; 51(16):4170-5. PubMed ID: 1868438
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inactivation of aldophosphamide by human aldehyde dehydrogenase isozyme 3.
    Giorgianni F; Bridson PK; Sorrentino BP; Pohl J; Blakley RL
    Biochem Pharmacol; 2000 Aug; 60(3):325-38. PubMed ID: 10856427
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Half-life of oxazaphosphorines in biological fluids.
    Sladek NE; Powers JF; Grage GM
    Drug Metab Dispos; 1984; 12(5):553-9. PubMed ID: 6149904
    [TBL] [Abstract][Full Text] [Related]  

  • 9. NADPH-dependent reductases of the dog lens.
    Sato S; Kador PF
    Exp Eye Res; 1990 Jun; 50(6):629-34. PubMed ID: 2115452
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Inhibition by cyanamide of 4-hydroxycyclophosphamide/aldophosphamide oxidation to carboxyphosphamide.
    Domeyer BE; Sladek NE
    Biochem Pharmacol; 1981 Aug; 30(15):2065-73. PubMed ID: 7295327
    [No Abstract]   [Full Text] [Related]  

  • 11. Aldose reductase-catalyzed reduction of acrolein: implications in cyclophosphamide toxicity.
    Kolb NS; Hunsaker LA; Vander Jagt DL
    Mol Pharmacol; 1994 Apr; 45(4):797-801. PubMed ID: 8183257
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Conversion of 4-hydroperoxycyclophosphamide and 4-hydroxycyclophosphamide to phosphoramide mustard and acrolein mediated by bifunctional catalysis.
    Low JE; Borch RF; Sladek NE
    Cancer Res; 1982 Mar; 42(3):830-7. PubMed ID: 7059981
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Purification and properties of aldehyde reductases from human placenta.
    Das B; Srivastava SK
    Biochim Biophys Acta; 1985 Jul; 840(3):324-33. PubMed ID: 3890957
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Detoxification of cyclophosphamide by human aldehyde dehydrogenase isozymes.
    von Eitzen U; Meier-Tackmann D; Agarwal DP; Goedde HW
    Cancer Lett; 1994 Jan; 76(1):45-9. PubMed ID: 8124665
    [TBL] [Abstract][Full Text] [Related]  

  • 15. NMR spectroscopic studies of intermediary metabolites of cyclophosphamide. A comprehensive kinetic analysis of the interconversion of cis- and trans-4-hydroxycyclophosphamide with aldophosphamide and the concomitant partitioning of aldophosphamide between irreversible fragmentation and reversible conjugation pathways.
    Zon G; Ludeman SM; Brandt JA; Boyd VL; Ozkan G; Egan W; Shao KL
    J Med Chem; 1984 Apr; 27(4):466-85. PubMed ID: 6708049
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Monkey 3-deoxyglucosone reductase: tissue distribution and purification of three multiple forms of the kidney enzyme that are identical with dihydrodiol dehydrogenase, aldehyde reductase, and aldose reductase.
    Sato K; Inazu A; Yamaguchi S; Nakayama T; Deyashiki Y; Sawada H; Hara A
    Arch Biochem Biophys; 1993 Dec; 307(2):286-94. PubMed ID: 8274014
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Aldose reductase the major protein associated with naphthalene dihydrodiol dehydrogenase activity in rat lens.
    Sato S
    Invest Ophthalmol Vis Sci; 1993 Oct; 34(11):3172-8. PubMed ID: 8407226
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Stereospecificity of the hydrogen transfer catalyzed by human placental aldose reductase.
    Feldman HB; Szczepanik PA; Havre P; Corrall RJ; Yu LC; Rodman HM; Rosner BA; Klein PD; Landau BR
    Biochim Biophys Acta; 1977 Jan; 480(1):14-20. PubMed ID: 12822
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Aldose and aldehyde reductase exhibit isocorticosteroid reductase activity.
    Wermuth B; Monder C
    Eur J Biochem; 1983 Mar; 131(2):423-6. PubMed ID: 6403351
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Purification and characterization of human testis aldose and aldehyde reductase.
    Tanimoto T; Ohta M; Tanaka A; Ikemoto I; Machida T
    Int J Biochem; 1991; 23(4):421-8. PubMed ID: 1901806
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.