212 related articles for article (PubMed ID: 821945)
1. Metabolism of benzo(a)pyrene and benzo (a)pyrene derivatives to mutagenic products by highly purified hepatic microsomal enzymes.
Wood AW; Levin W; Lu AY; Yagi H; Hernandez O; Jerina DM; Conney AH
J Biol Chem; 1976 Aug; 251(16):4882-90. PubMed ID: 821945
[TBL] [Abstract][Full Text] [Related]
2. Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides.
Thakker DR; Yagi H; Lu AY; Levin W; Conney AH
Proc Natl Acad Sci U S A; 1976 Oct; 73(10):3381-5. PubMed ID: 1068451
[TBL] [Abstract][Full Text] [Related]
3. Stereo-selectivity and regio-selectivity in the metabolism of 7,8-dihydrobenzo[a]pyrene by cytochrome P450, epoxide hydrolase and hepatic microsomes from 3-methylcholanthrene-treated rats.
Adams JD; Yagi H; Levin W; Jerina DM
Chem Biol Interact; 1995 Mar; 95(1-2):57-77. PubMed ID: 7697754
[TBL] [Abstract][Full Text] [Related]
4. Mutagenicity and cytotoxicity of benzo(a)pyrene benzo-ring epoxides.
Wood AW; Wislocki PG; Chang RL; Levin W; Lu AY; Yagi J; Hernandez O; Herina DM; Conney AH
Cancer Res; 1976 Sep; 36(9 pt.1):3358-66. PubMed ID: 788899
[TBL] [Abstract][Full Text] [Related]
5. Inhibitory effect of 3-hydroxybenzo(a)pyrene on the mutagenicity and tumorigenicity of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene.
Huang MT; Wood AW; Chang RL; Yagi H; Sayer JM; Jerina DM; Conney AH
Cancer Res; 1986 Feb; 46(2):558-66. PubMed ID: 3079665
[TBL] [Abstract][Full Text] [Related]
6. Mutagenesis of certain activated carcinogens in vitro associated with genetically mediated increases in monooxygenase activity and cytochrome P 1-450.
Felton JS; Nebert DW
J Biol Chem; 1975 Sep; 250(17):6769-78. PubMed ID: 808546
[TBL] [Abstract][Full Text] [Related]
7. Formation in isolated rat liver microsomes and nuclei of benzo(a)pyrene metabolites that bind to DNA.
Jernström B; Vadi H; Orrenius S
Cancer Res; 1976 Nov; 36(11 Pt 1):4107-13. PubMed ID: 10077
[TBL] [Abstract][Full Text] [Related]
8. Mutagenicity of the bay-region diol-epoxides and other benzo-ring derivatives of dibenzo(a,h)pyrene and dibenzo(a,i)pyrene.
Wood AW; Chang RL; Levin W; Ryan DE; Thomas PE; Lehr RE; Kumar S; Sardella DJ; Boger E; Yagi H; Sayer JM; Jerina DM; Conney AH
Cancer Res; 1981 Jul; 41(7):2589-97. PubMed ID: 7018665
[TBL] [Abstract][Full Text] [Related]
9. Metabolic activation to a mutagen of 3-hydroxy-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene, a secondary metabolite of benzo[a]pyrene.
Glatt H; Seidel A; Ribeiro O; Kirkby C; Hirom P; Oesch F
Carcinogenesis; 1987 Nov; 8(11):1621-7. PubMed ID: 3311446
[TBL] [Abstract][Full Text] [Related]
10. Effects of inducers and epoxide hydrase on the metabolism of benzo(a)pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography.
Holder G; Yagi H; Dansette P; Jerina DM; Levin W; Lu AY; Conney AH
Proc Natl Acad Sci U S A; 1974 Nov; 71(11):4356-60. PubMed ID: 4530987
[TBL] [Abstract][Full Text] [Related]
11. Covalent binding of benzo[a]pyrene to cytochrome P-450 beta NF-B2 and other proteins in reconstituted mixed-function oxidase systems.
Schelin C; Wallin H; Halpert J; Jergil B
Chem Biol Interact; 1984 May; 49(3):269-81. PubMed ID: 6327095
[TBL] [Abstract][Full Text] [Related]
12. Metabolism of benzo[a]pyrene to trans-7,8-dihydroxy-7, 8-dihydrobenzo[a]pyrene by recombinant human cytochrome P450 1B1 and purified liver epoxide hydrolase.
Shimada T; Gillam EM; Oda Y; Tsumura F; Sutter TR; Guengerich FP; Inoue K
Chem Res Toxicol; 1999 Jul; 12(7):623-9. PubMed ID: 10409402
[TBL] [Abstract][Full Text] [Related]
13. Different patterns of benzo[a]pyrene metabolism of purified cytochromes P-450 from methylcholanthrene, beta-naphthoflavone and phenobarbital treated rats.
Gozukara EM; Guengerich FP; Miller H; Gelboin HV
Carcinogenesis; 1982; 3(2):129-33. PubMed ID: 6279326
[TBL] [Abstract][Full Text] [Related]
14. Regio- and stereoselectivity of various forms of purified cytochrome P-450 in the metabolism of benzo[a]pyrene and (-) trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene as shown by product formation and binding to DNA.
Deutsch J; Leutz JC; Yang SK; Gelboin HV; Chiang YL; Vatsis KP; Coon MJ
Proc Natl Acad Sci U S A; 1978 Jul; 75(7):3123-7. PubMed ID: 277915
[TBL] [Abstract][Full Text] [Related]
15. Species-specific enhancement by 7,8-benzoflavone of hepatic microsomal metabolism of benzo[e]pyrene 9,10-dihydrodiol to bay-region diol epoxides.
Thakker DR; Levin W; Buening M; Yagi H; Lehr RE; Wood AW; Conney AH; Jerina DM
Cancer Res; 1981 Apr; 41(4):1389-96. PubMed ID: 7194138
[TBL] [Abstract][Full Text] [Related]
16. Relationship between benzo(a)pyrene-induced DNA base modification and frequency of reverse mutations in mutant strains of Salmonella typhimurium.
Fahl WE; Scarpelli DG; Gill K
Cancer Res; 1981 Sep; 41(9 Pt 1):3400-6. PubMed ID: 6266655
[TBL] [Abstract][Full Text] [Related]
17. Effects of a 6-fluoro substituent on the metabolism of benzo(a)pyrene 7,8-dihydrodiol to bay-region diol epoxides by rat liver enzymes.
Thakker DR; Yagi H; Sayer JM; Kapur U; Levin W; Chang RL; Wood AW; Conney AH; Jerina DM
J Biol Chem; 1984 Sep; 259(18):11249-56. PubMed ID: 6432795
[TBL] [Abstract][Full Text] [Related]
18. Benzo[a]pyrene metabolism by purified cytochrome P-450 from 3-methylcholanthrene-treated rats.
Sagami I; Ohmachi T; Fujii H; Watanabe M
Xenobiotica; 1987 Feb; 17(2):189-98. PubMed ID: 3564534
[TBL] [Abstract][Full Text] [Related]
19. Benzo(a)pyrene metabolism by purified forms of rabbit liver microsomal cytochrome P-450, cytochrome b5 and epoxide hydrase in reconstituted phospholipid vesicles.
Brunström A; Ingelman-Sundberg M
Biochem Biophys Res Commun; 1980 Jul; 95(1):431-9. PubMed ID: 7417266
[No Abstract] [Full Text] [Related]
20. Mutagenicity and cytotoxicity of benzo(a)pyrene arene oxides, phenols, quinones, and dihydrodiols in bacterial and mammalian cells.
Wislocki PG; Wood AW; Chang RL; Levin W; Yagi H; Hernandez O; Dansette PM; Herina DM; Conney AH
Cancer Res; 1976 Sep; 36(9 pt.1):3350-7. PubMed ID: 788898
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]